Double effort test for evaluation of aerobic capacity of diet-induced obese rats
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1517-86922013000300014 http://hdl.handle.net/11449/76499 |
Resumo: | Introduction: The literature lacks studies about lactate actions and some limitations in studies involving healthy individuals or patients with some metabolic disorder. Objectives: This study aimed to evaluate the protocol of double effort test for obese-induced rats. Methods: Fourteen male Wistar rats were divided into two groups: Control (Con) and Obese (Obe). The control group was fed with standard chow and water ad libitum. The obese group was fed with standard chow, water ad libitum and hyperlipidic diet. Twelve weeks after the beginning of the hyperlipidic diet, insulin tolerance test, Maximal Lactate Steady State (MLSS) test and the double efforts test were performed. Results: The diet was effective to promote obesity. The obese group decreased insulin sensitivity in approximately 19% (Con = 2.156 ± 0.1187 AU vs Obe = 1.742 ± 0.1551 AU). The lactate concentration and velocity of anaerobic threshold at MLSS test were 3.780 ± 0.09 mmol/L e 18 m.min-1 in both groups. The velocity of anaerobic threshold estimated by double efforts test was 15.59±0.653 m.min-1 in Con group control animals and 16.42±0.672 m.min-1 in Obe group. The double effort test underestimated around 13% and 8.7% the aerobic capacity in control and obese groups respectively, however, presented significant correlation with MLSS (r = 0,88; P < 0,0075 controls / r = 0,92; P < 0,0031 obese). Conclusion: So, the double effort test can be an interesting alternative to evaluate the aerobic capacity for both healthy sedentary and obese animals. |
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Double effort test for evaluation of aerobic capacity of diet-induced obese ratsLactic acidObesityRunningIntroduction: The literature lacks studies about lactate actions and some limitations in studies involving healthy individuals or patients with some metabolic disorder. Objectives: This study aimed to evaluate the protocol of double effort test for obese-induced rats. Methods: Fourteen male Wistar rats were divided into two groups: Control (Con) and Obese (Obe). The control group was fed with standard chow and water ad libitum. The obese group was fed with standard chow, water ad libitum and hyperlipidic diet. Twelve weeks after the beginning of the hyperlipidic diet, insulin tolerance test, Maximal Lactate Steady State (MLSS) test and the double efforts test were performed. Results: The diet was effective to promote obesity. The obese group decreased insulin sensitivity in approximately 19% (Con = 2.156 ± 0.1187 AU vs Obe = 1.742 ± 0.1551 AU). The lactate concentration and velocity of anaerobic threshold at MLSS test were 3.780 ± 0.09 mmol/L e 18 m.min-1 in both groups. The velocity of anaerobic threshold estimated by double efforts test was 15.59±0.653 m.min-1 in Con group control animals and 16.42±0.672 m.min-1 in Obe group. The double effort test underestimated around 13% and 8.7% the aerobic capacity in control and obese groups respectively, however, presented significant correlation with MLSS (r = 0,88; P < 0,0075 controls / r = 0,92; P < 0,0031 obese). Conclusion: So, the double effort test can be an interesting alternative to evaluate the aerobic capacity for both healthy sedentary and obese animals.Department of Physiotherapy Laboratory of Research in Physiology State University of São Paulo, Júlio de Mesquita FilhoPhysical Education and Sports School of Ribeirão Preto USPDepartment of Physiotherapy Laboratory of Research in Physiology State University of São Paulo, Júlio de Mesquita FilhoUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Brandão, Bruna Brasil [UNESP]de Souza, Lidiane Moreira [UNESP]Trombetta, Beatriz de Novais Oliveira [UNESP]Pastre, Carlos Marcelo [UNESP]Papoti, MarceloSeraphim, Patricia Monteiro [UNESP]2014-05-27T11:30:37Z2014-05-27T11:30:37Z2013-09-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article214-218application/pdfhttp://dx.doi.org/10.1590/S1517-86922013000300014Revista Brasileira de Medicina do Esporte, v. 19, n. 3, p. 214-218, 2013.1517-8692http://hdl.handle.net/11449/7649910.1590/S1517-86922013000300014S1517-86922013000300014WOS:0003235010000142-s2.0-848830688222-s2.0-84883068822.pdf276139654405860604110085990708710000-0003-2145-6640Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Brasileira de Medicina do Esporte0.2700,185info:eu-repo/semantics/openAccess2024-06-18T18:44:03Zoai:repositorio.unesp.br:11449/76499Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:54:43.116789Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
title |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
spellingShingle |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats Brandão, Bruna Brasil [UNESP] Lactic acid Obesity Running |
title_short |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
title_full |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
title_fullStr |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
title_full_unstemmed |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
title_sort |
Double effort test for evaluation of aerobic capacity of diet-induced obese rats |
author |
Brandão, Bruna Brasil [UNESP] |
author_facet |
Brandão, Bruna Brasil [UNESP] de Souza, Lidiane Moreira [UNESP] Trombetta, Beatriz de Novais Oliveira [UNESP] Pastre, Carlos Marcelo [UNESP] Papoti, Marcelo Seraphim, Patricia Monteiro [UNESP] |
author_role |
author |
author2 |
de Souza, Lidiane Moreira [UNESP] Trombetta, Beatriz de Novais Oliveira [UNESP] Pastre, Carlos Marcelo [UNESP] Papoti, Marcelo Seraphim, Patricia Monteiro [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Brandão, Bruna Brasil [UNESP] de Souza, Lidiane Moreira [UNESP] Trombetta, Beatriz de Novais Oliveira [UNESP] Pastre, Carlos Marcelo [UNESP] Papoti, Marcelo Seraphim, Patricia Monteiro [UNESP] |
dc.subject.por.fl_str_mv |
Lactic acid Obesity Running |
topic |
Lactic acid Obesity Running |
description |
Introduction: The literature lacks studies about lactate actions and some limitations in studies involving healthy individuals or patients with some metabolic disorder. Objectives: This study aimed to evaluate the protocol of double effort test for obese-induced rats. Methods: Fourteen male Wistar rats were divided into two groups: Control (Con) and Obese (Obe). The control group was fed with standard chow and water ad libitum. The obese group was fed with standard chow, water ad libitum and hyperlipidic diet. Twelve weeks after the beginning of the hyperlipidic diet, insulin tolerance test, Maximal Lactate Steady State (MLSS) test and the double efforts test were performed. Results: The diet was effective to promote obesity. The obese group decreased insulin sensitivity in approximately 19% (Con = 2.156 ± 0.1187 AU vs Obe = 1.742 ± 0.1551 AU). The lactate concentration and velocity of anaerobic threshold at MLSS test were 3.780 ± 0.09 mmol/L e 18 m.min-1 in both groups. The velocity of anaerobic threshold estimated by double efforts test was 15.59±0.653 m.min-1 in Con group control animals and 16.42±0.672 m.min-1 in Obe group. The double effort test underestimated around 13% and 8.7% the aerobic capacity in control and obese groups respectively, however, presented significant correlation with MLSS (r = 0,88; P < 0,0075 controls / r = 0,92; P < 0,0031 obese). Conclusion: So, the double effort test can be an interesting alternative to evaluate the aerobic capacity for both healthy sedentary and obese animals. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-09-02 2014-05-27T11:30:37Z 2014-05-27T11:30:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1517-86922013000300014 Revista Brasileira de Medicina do Esporte, v. 19, n. 3, p. 214-218, 2013. 1517-8692 http://hdl.handle.net/11449/76499 10.1590/S1517-86922013000300014 S1517-86922013000300014 WOS:000323501000014 2-s2.0-84883068822 2-s2.0-84883068822.pdf 2761396544058606 0411008599070871 0000-0003-2145-6640 |
url |
http://dx.doi.org/10.1590/S1517-86922013000300014 http://hdl.handle.net/11449/76499 |
identifier_str_mv |
Revista Brasileira de Medicina do Esporte, v. 19, n. 3, p. 214-218, 2013. 1517-8692 10.1590/S1517-86922013000300014 S1517-86922013000300014 WOS:000323501000014 2-s2.0-84883068822 2-s2.0-84883068822.pdf 2761396544058606 0411008599070871 0000-0003-2145-6640 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Revista Brasileira de Medicina do Esporte 0.270 0,185 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
214-218 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128997800804352 |