The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.cbpa.2019.05.002 http://hdl.handle.net/11449/186041 |
Resumo: | Pacu is a tropical fish with important value to aquaculture. During cellular metabolism, reactive oxygen species (ROS) are produced, which can influence muscle growth. Resveratrol is an effective antioxidant that scavenges ROS and can modulate physical performance preventing oxidative stress. We investigated the effects of resveratrol and exercise on pacu muscle growth characteristics. Four groups were used: fish fed with control diet/without exercise (C); fish fed with control diet/subjected to exercise (CE); fish fed resveratrol-supplemented diet/without exercise (R); and fish fed resveratrol-supplemented diet/subjected to exercise (RE). At 30 days, the RE group presented a significant increase in body weight, fewer muscle fibers in the 20-40 mu m and more fibers in the > 60 mu m diameter class compared to the C group. At day 7, catalase activity decreased in CE and RE groups. Superoxide dismutase activity decreased only in the CE group. Myod and rotor gene expression was higher in R and RE and igf-1 was up-regulated in the RE group. Murf1a level decreased in CE, R, and RE, while sdha expression was higher in the RE group. We suggest that resveratrol in combination with exercise was beneficial for muscle growth and metabolism, increasing the expression levels of genes related to muscle anabolism and oxidative metabolism, besides the decrease of catabolic gene expression. Notably, all of these changes occurred together with muscle hypertrophy and increased body weight. Our results show a positive application for resveratrol in association with exercise as a strategy to improve the growth performance of juvenile pacus. |
id |
UNSP_76b96ba7fa84095a6302f9914dba6540 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/186041 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus)Skeletal muscleFishResveratrolExercisePacu is a tropical fish with important value to aquaculture. During cellular metabolism, reactive oxygen species (ROS) are produced, which can influence muscle growth. Resveratrol is an effective antioxidant that scavenges ROS and can modulate physical performance preventing oxidative stress. We investigated the effects of resveratrol and exercise on pacu muscle growth characteristics. Four groups were used: fish fed with control diet/without exercise (C); fish fed with control diet/subjected to exercise (CE); fish fed resveratrol-supplemented diet/without exercise (R); and fish fed resveratrol-supplemented diet/subjected to exercise (RE). At 30 days, the RE group presented a significant increase in body weight, fewer muscle fibers in the 20-40 mu m and more fibers in the > 60 mu m diameter class compared to the C group. At day 7, catalase activity decreased in CE and RE groups. Superoxide dismutase activity decreased only in the CE group. Myod and rotor gene expression was higher in R and RE and igf-1 was up-regulated in the RE group. Murf1a level decreased in CE, R, and RE, while sdha expression was higher in the RE group. We suggest that resveratrol in combination with exercise was beneficial for muscle growth and metabolism, increasing the expression levels of genes related to muscle anabolism and oxidative metabolism, besides the decrease of catabolic gene expression. Notably, all of these changes occurred together with muscle hypertrophy and increased body weight. Our results show a positive application for resveratrol in association with exercise as a strategy to improve the growth performance of juvenile pacus.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Sao Paulo State Univ, UNESP, Inst Biosci, Dept Morphol, Botucatu, SP, BrazilSao Paulo State Univ, UNESP, CAUNESP, Aquaculture Ctr, Jaboticabal, SP, BrazilSao Paulo State Univ, UNESP, FMVZ, Dept Breeding & Anim Nutr, Botucatu, SP, BrazilSao Paulo State Univ, UNESP, Inst Biosci, Dept Chem & Biochem, Botucatu, SP, BrazilUniv Western Sao Paulo, UNOESTE, Dept Biol, Presidente Prudente, SP, BrazilAPTA, Sao Paulo Agcy Agribusiness Technol, Presidente Prudente, SP, BrazilSao Paulo State Univ, UNESP, Inst Biosci, Dept Morphol, Botucatu, SP, BrazilSao Paulo State Univ, UNESP, CAUNESP, Aquaculture Ctr, Jaboticabal, SP, BrazilSao Paulo State Univ, UNESP, FMVZ, Dept Breeding & Anim Nutr, Botucatu, SP, BrazilSao Paulo State Univ, UNESP, Inst Biosci, Dept Chem & Biochem, Botucatu, SP, BrazilCNPq: 447233/2014CNPq: 302656/2015-4Elsevier B.V.Universidade Estadual Paulista (Unesp)Univ Western Sao PauloAPTASimoes Salomao, Rondinelle Artur [UNESP]De Paula, Tassiana Gutierrez [UNESP]Thomazini Zanella, Bruna Tereza [UNESP]Pucci Figueiredo Carvalho, Pedro Luis [UNESP]Silva Duran, Bruno Oliveira da [UNESP]Valente, Jessica Silvino [UNESP]Almeida Fantinatti, Bruno Evaristo de [UNESP]Fernandes, Ana Angelica [UNESP]Barros, Margarida Maria [UNESP]Mareco, Edson AssuncaoCarvalho, Robson Francisco [UNESP]Santos, Vander Bruno dosDal-Pai-Silva, Maeli [UNESP]2019-10-04T12:40:47Z2019-10-04T12:40:47Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article46-55http://dx.doi.org/10.1016/j.cbpa.2019.05.002Comparative Biochemistry And Physiology A-molecular & Integrative Physiology. New York: Elsevier Science Inc, v. 235, p. 46-55, 2019.1095-6433http://hdl.handle.net/11449/18604110.1016/j.cbpa.2019.05.002WOS:0004815611000249349360966928688Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengComparative Biochemistry And Physiology A-molecular & Integrative Physiologyinfo:eu-repo/semantics/openAccess2021-10-22T22:24:09Zoai:repositorio.unesp.br:11449/186041Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:01:24.048435Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
title |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
spellingShingle |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) Simoes Salomao, Rondinelle Artur [UNESP] Skeletal muscle Fish Resveratrol Exercise |
title_short |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
title_full |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
title_fullStr |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
title_full_unstemmed |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
title_sort |
The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus) |
author |
Simoes Salomao, Rondinelle Artur [UNESP] |
author_facet |
Simoes Salomao, Rondinelle Artur [UNESP] De Paula, Tassiana Gutierrez [UNESP] Thomazini Zanella, Bruna Tereza [UNESP] Pucci Figueiredo Carvalho, Pedro Luis [UNESP] Silva Duran, Bruno Oliveira da [UNESP] Valente, Jessica Silvino [UNESP] Almeida Fantinatti, Bruno Evaristo de [UNESP] Fernandes, Ana Angelica [UNESP] Barros, Margarida Maria [UNESP] Mareco, Edson Assuncao Carvalho, Robson Francisco [UNESP] Santos, Vander Bruno dos Dal-Pai-Silva, Maeli [UNESP] |
author_role |
author |
author2 |
De Paula, Tassiana Gutierrez [UNESP] Thomazini Zanella, Bruna Tereza [UNESP] Pucci Figueiredo Carvalho, Pedro Luis [UNESP] Silva Duran, Bruno Oliveira da [UNESP] Valente, Jessica Silvino [UNESP] Almeida Fantinatti, Bruno Evaristo de [UNESP] Fernandes, Ana Angelica [UNESP] Barros, Margarida Maria [UNESP] Mareco, Edson Assuncao Carvalho, Robson Francisco [UNESP] Santos, Vander Bruno dos Dal-Pai-Silva, Maeli [UNESP] |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Univ Western Sao Paulo APTA |
dc.contributor.author.fl_str_mv |
Simoes Salomao, Rondinelle Artur [UNESP] De Paula, Tassiana Gutierrez [UNESP] Thomazini Zanella, Bruna Tereza [UNESP] Pucci Figueiredo Carvalho, Pedro Luis [UNESP] Silva Duran, Bruno Oliveira da [UNESP] Valente, Jessica Silvino [UNESP] Almeida Fantinatti, Bruno Evaristo de [UNESP] Fernandes, Ana Angelica [UNESP] Barros, Margarida Maria [UNESP] Mareco, Edson Assuncao Carvalho, Robson Francisco [UNESP] Santos, Vander Bruno dos Dal-Pai-Silva, Maeli [UNESP] |
dc.subject.por.fl_str_mv |
Skeletal muscle Fish Resveratrol Exercise |
topic |
Skeletal muscle Fish Resveratrol Exercise |
description |
Pacu is a tropical fish with important value to aquaculture. During cellular metabolism, reactive oxygen species (ROS) are produced, which can influence muscle growth. Resveratrol is an effective antioxidant that scavenges ROS and can modulate physical performance preventing oxidative stress. We investigated the effects of resveratrol and exercise on pacu muscle growth characteristics. Four groups were used: fish fed with control diet/without exercise (C); fish fed with control diet/subjected to exercise (CE); fish fed resveratrol-supplemented diet/without exercise (R); and fish fed resveratrol-supplemented diet/subjected to exercise (RE). At 30 days, the RE group presented a significant increase in body weight, fewer muscle fibers in the 20-40 mu m and more fibers in the > 60 mu m diameter class compared to the C group. At day 7, catalase activity decreased in CE and RE groups. Superoxide dismutase activity decreased only in the CE group. Myod and rotor gene expression was higher in R and RE and igf-1 was up-regulated in the RE group. Murf1a level decreased in CE, R, and RE, while sdha expression was higher in the RE group. We suggest that resveratrol in combination with exercise was beneficial for muscle growth and metabolism, increasing the expression levels of genes related to muscle anabolism and oxidative metabolism, besides the decrease of catabolic gene expression. Notably, all of these changes occurred together with muscle hypertrophy and increased body weight. Our results show a positive application for resveratrol in association with exercise as a strategy to improve the growth performance of juvenile pacus. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-04T12:40:47Z 2019-10-04T12:40:47Z 2019-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.cbpa.2019.05.002 Comparative Biochemistry And Physiology A-molecular & Integrative Physiology. New York: Elsevier Science Inc, v. 235, p. 46-55, 2019. 1095-6433 http://hdl.handle.net/11449/186041 10.1016/j.cbpa.2019.05.002 WOS:000481561100024 9349360966928688 |
url |
http://dx.doi.org/10.1016/j.cbpa.2019.05.002 http://hdl.handle.net/11449/186041 |
identifier_str_mv |
Comparative Biochemistry And Physiology A-molecular & Integrative Physiology. New York: Elsevier Science Inc, v. 235, p. 46-55, 2019. 1095-6433 10.1016/j.cbpa.2019.05.002 WOS:000481561100024 9349360966928688 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Comparative Biochemistry And Physiology A-molecular & Integrative Physiology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
46-55 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128886072934400 |