Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws

Detalhes bibliográficos
Autor(a) principal: Conte-Neto, Nicolau [UNESP]
Data de Publicação: 2012
Outros Autores: Bastos, Alliny Souza [UNESP], Marcantonio, Rosemary Adriana Chierici [UNESP], Marcantonio Júnior, Elcio [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/1746-160X-8-5
http://hdl.handle.net/11449/16046
Resumo: This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation.
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spelling Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jawsRheumatoid arthritisBisphosphonateJawsOsteonecrosisThis literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation.UNESP Univ Estadual Paulista, Sch Dent, Dept Diag & Surg, Div Periodontol, BR-14801903 Araraquara, SP, BrazilUNESP Univ Estadual Paulista, Sch Dent, Dept Diag & Surg, Div Periodontol, BR-14801903 Araraquara, SP, BrazilBiomed Central Ltd.Universidade Estadual Paulista (Unesp)Conte-Neto, Nicolau [UNESP]Bastos, Alliny Souza [UNESP]Marcantonio, Rosemary Adriana Chierici [UNESP]Marcantonio Júnior, Elcio [UNESP]2014-05-20T13:45:36Z2014-05-20T13:45:36Z2012-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://dx.doi.org/10.1186/1746-160X-8-5Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012.1746-160Xhttp://hdl.handle.net/11449/1604610.1186/1746-160X-8-5WOS:000313281200001WOS000313281200001.pdf35340443998840356100859465871929Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengHead & Face Medicine1.606info:eu-repo/semantics/openAccess2024-09-26T15:21:29Zoai:repositorio.unesp.br:11449/16046Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-26T15:21:29Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
title Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
spellingShingle Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
Conte-Neto, Nicolau [UNESP]
Rheumatoid arthritis
Bisphosphonate
Jaws
Osteonecrosis
title_short Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
title_full Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
title_fullStr Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
title_full_unstemmed Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
title_sort Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
author Conte-Neto, Nicolau [UNESP]
author_facet Conte-Neto, Nicolau [UNESP]
Bastos, Alliny Souza [UNESP]
Marcantonio, Rosemary Adriana Chierici [UNESP]
Marcantonio Júnior, Elcio [UNESP]
author_role author
author2 Bastos, Alliny Souza [UNESP]
Marcantonio, Rosemary Adriana Chierici [UNESP]
Marcantonio Júnior, Elcio [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Conte-Neto, Nicolau [UNESP]
Bastos, Alliny Souza [UNESP]
Marcantonio, Rosemary Adriana Chierici [UNESP]
Marcantonio Júnior, Elcio [UNESP]
dc.subject.por.fl_str_mv Rheumatoid arthritis
Bisphosphonate
Jaws
Osteonecrosis
topic Rheumatoid arthritis
Bisphosphonate
Jaws
Osteonecrosis
description This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation.
publishDate 2012
dc.date.none.fl_str_mv 2012-03-01
2014-05-20T13:45:36Z
2014-05-20T13:45:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/1746-160X-8-5
Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012.
1746-160X
http://hdl.handle.net/11449/16046
10.1186/1746-160X-8-5
WOS:000313281200001
WOS000313281200001.pdf
3534044399884035
6100859465871929
url http://dx.doi.org/10.1186/1746-160X-8-5
http://hdl.handle.net/11449/16046
identifier_str_mv Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012.
1746-160X
10.1186/1746-160X-8-5
WOS:000313281200001
WOS000313281200001.pdf
3534044399884035
6100859465871929
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Head & Face Medicine
1.606
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10
application/pdf
dc.publisher.none.fl_str_mv Biomed Central Ltd.
publisher.none.fl_str_mv Biomed Central Ltd.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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