Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1746-160X-8-5 http://hdl.handle.net/11449/16046 |
Resumo: | This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation. |
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Repositório Institucional da UNESP |
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Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jawsRheumatoid arthritisBisphosphonateJawsOsteonecrosisThis literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation.UNESP Univ Estadual Paulista, Sch Dent, Dept Diag & Surg, Div Periodontol, BR-14801903 Araraquara, SP, BrazilUNESP Univ Estadual Paulista, Sch Dent, Dept Diag & Surg, Div Periodontol, BR-14801903 Araraquara, SP, BrazilBiomed Central Ltd.Universidade Estadual Paulista (Unesp)Conte-Neto, Nicolau [UNESP]Bastos, Alliny Souza [UNESP]Marcantonio, Rosemary Adriana Chierici [UNESP]Marcantonio Júnior, Elcio [UNESP]2014-05-20T13:45:36Z2014-05-20T13:45:36Z2012-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://dx.doi.org/10.1186/1746-160X-8-5Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012.1746-160Xhttp://hdl.handle.net/11449/1604610.1186/1746-160X-8-5WOS:000313281200001WOS000313281200001.pdf35340443998840356100859465871929Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengHead & Face Medicine1.606info:eu-repo/semantics/openAccess2024-09-26T15:21:29Zoai:repositorio.unesp.br:11449/16046Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-26T15:21:29Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
title |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
spellingShingle |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws Conte-Neto, Nicolau [UNESP] Rheumatoid arthritis Bisphosphonate Jaws Osteonecrosis |
title_short |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
title_full |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
title_fullStr |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
title_full_unstemmed |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
title_sort |
Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws |
author |
Conte-Neto, Nicolau [UNESP] |
author_facet |
Conte-Neto, Nicolau [UNESP] Bastos, Alliny Souza [UNESP] Marcantonio, Rosemary Adriana Chierici [UNESP] Marcantonio Júnior, Elcio [UNESP] |
author_role |
author |
author2 |
Bastos, Alliny Souza [UNESP] Marcantonio, Rosemary Adriana Chierici [UNESP] Marcantonio Júnior, Elcio [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Conte-Neto, Nicolau [UNESP] Bastos, Alliny Souza [UNESP] Marcantonio, Rosemary Adriana Chierici [UNESP] Marcantonio Júnior, Elcio [UNESP] |
dc.subject.por.fl_str_mv |
Rheumatoid arthritis Bisphosphonate Jaws Osteonecrosis |
topic |
Rheumatoid arthritis Bisphosphonate Jaws Osteonecrosis |
description |
This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-03-01 2014-05-20T13:45:36Z 2014-05-20T13:45:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1746-160X-8-5 Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012. 1746-160X http://hdl.handle.net/11449/16046 10.1186/1746-160X-8-5 WOS:000313281200001 WOS000313281200001.pdf 3534044399884035 6100859465871929 |
url |
http://dx.doi.org/10.1186/1746-160X-8-5 http://hdl.handle.net/11449/16046 |
identifier_str_mv |
Head & Face Medicine. London: Biomed Central Ltd., v. 8, p. 10, 2012. 1746-160X 10.1186/1746-160X-8-5 WOS:000313281200001 WOS000313281200001.pdf 3534044399884035 6100859465871929 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Head & Face Medicine 1.606 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
10 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1813546435633741824 |