Can mechanical agitation induce stable physicochemical changes on a solvent?
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/232160 |
Resumo: | Why do serial agitations are so important to prepare a homeopathic medicine? This question has been discussed for two centuries but it still remains opened. Accordingly some experimental evidences, agitated (and diluted) samples have different biological effects when compared with equivalent ones kept at rest or diluted without vigorous serial agitations. To explain these differences many hypotheses have been proposed considering the increase on the solvent's gasification, cavitation effects, nanobubbles formation, mechanically or thermally induced chemical reactions, nanoclusters formation and silica release, among others. These hypotheses could explain some physicochemical changes induced by agitation. However, these changes have not always been easily observed or understood. Further, homeopathic medicines are able to provoke biological responses in live systems and, until now, there isn't one even reliable hypothesis or evidence able to correlate their physicochemical properties with biological activity. To start addressing this problem, we focused on some physicochemical changes induced by agitation. A KMnO4 solution was submitted to three different modes of mechanical agitation (simulated arm, vertical shaking and hammer). Since this chemical reaction is dependent on agitation, we followed the rate of color change (speed of reaction) through the absorbance values at some peaks (visible spectrum), for each different agitation mode. We have concluded that this chemical model can be useful to gather more information about the dynamical physicochemical changes induced by serial agitations. However, no biological correlation can be established from these results. |
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Can mechanical agitation induce stable physicochemical changes on a solvent?AgitationChemical reactionKMnO4SpectroscopyWhy do serial agitations are so important to prepare a homeopathic medicine? This question has been discussed for two centuries but it still remains opened. Accordingly some experimental evidences, agitated (and diluted) samples have different biological effects when compared with equivalent ones kept at rest or diluted without vigorous serial agitations. To explain these differences many hypotheses have been proposed considering the increase on the solvent's gasification, cavitation effects, nanobubbles formation, mechanically or thermally induced chemical reactions, nanoclusters formation and silica release, among others. These hypotheses could explain some physicochemical changes induced by agitation. However, these changes have not always been easily observed or understood. Further, homeopathic medicines are able to provoke biological responses in live systems and, until now, there isn't one even reliable hypothesis or evidence able to correlate their physicochemical properties with biological activity. To start addressing this problem, we focused on some physicochemical changes induced by agitation. A KMnO4 solution was submitted to three different modes of mechanical agitation (simulated arm, vertical shaking and hammer). Since this chemical reaction is dependent on agitation, we followed the rate of color change (speed of reaction) through the absorbance values at some peaks (visible spectrum), for each different agitation mode. We have concluded that this chemical model can be useful to gather more information about the dynamical physicochemical changes induced by serial agitations. However, no biological correlation can be established from these results.Univ. Estadual Paulista - UNESP, GuaratinguetáUniv. Estadual Paulista - UNESP, GuaratinguetáUniversidade Estadual Paulista (UNESP)Zacharias, Carlos Renato [UNESP]de França Silva, Mariana [UNESP]2022-04-29T08:49:22Z2022-04-29T08:49:22Z2013-10-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article83International Journal of High Dilution Research, v. 12, n. 44, p. 83-, 2013.1982-6206http://hdl.handle.net/11449/2321602-s2.0-84886909342Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of High Dilution Researchinfo:eu-repo/semantics/openAccess2024-07-01T20:52:37Zoai:repositorio.unesp.br:11449/232160Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-07-01T20:52:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
title |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
spellingShingle |
Can mechanical agitation induce stable physicochemical changes on a solvent? Zacharias, Carlos Renato [UNESP] Agitation Chemical reaction KMnO4 Spectroscopy |
title_short |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
title_full |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
title_fullStr |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
title_full_unstemmed |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
title_sort |
Can mechanical agitation induce stable physicochemical changes on a solvent? |
author |
Zacharias, Carlos Renato [UNESP] |
author_facet |
Zacharias, Carlos Renato [UNESP] de França Silva, Mariana [UNESP] |
author_role |
author |
author2 |
de França Silva, Mariana [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Zacharias, Carlos Renato [UNESP] de França Silva, Mariana [UNESP] |
dc.subject.por.fl_str_mv |
Agitation Chemical reaction KMnO4 Spectroscopy |
topic |
Agitation Chemical reaction KMnO4 Spectroscopy |
description |
Why do serial agitations are so important to prepare a homeopathic medicine? This question has been discussed for two centuries but it still remains opened. Accordingly some experimental evidences, agitated (and diluted) samples have different biological effects when compared with equivalent ones kept at rest or diluted without vigorous serial agitations. To explain these differences many hypotheses have been proposed considering the increase on the solvent's gasification, cavitation effects, nanobubbles formation, mechanically or thermally induced chemical reactions, nanoclusters formation and silica release, among others. These hypotheses could explain some physicochemical changes induced by agitation. However, these changes have not always been easily observed or understood. Further, homeopathic medicines are able to provoke biological responses in live systems and, until now, there isn't one even reliable hypothesis or evidence able to correlate their physicochemical properties with biological activity. To start addressing this problem, we focused on some physicochemical changes induced by agitation. A KMnO4 solution was submitted to three different modes of mechanical agitation (simulated arm, vertical shaking and hammer). Since this chemical reaction is dependent on agitation, we followed the rate of color change (speed of reaction) through the absorbance values at some peaks (visible spectrum), for each different agitation mode. We have concluded that this chemical model can be useful to gather more information about the dynamical physicochemical changes induced by serial agitations. However, no biological correlation can be established from these results. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-25 2022-04-29T08:49:22Z 2022-04-29T08:49:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
International Journal of High Dilution Research, v. 12, n. 44, p. 83-, 2013. 1982-6206 http://hdl.handle.net/11449/232160 2-s2.0-84886909342 |
identifier_str_mv |
International Journal of High Dilution Research, v. 12, n. 44, p. 83-, 2013. 1982-6206 2-s2.0-84886909342 |
url |
http://hdl.handle.net/11449/232160 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of High Dilution Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
83 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803650129442373632 |