Eficácia da imunização profilática na Leucemia Viral Felina: revisão sistemática

• Autor(a) principal: Andrade, Jessica Thomé de [UNESP]
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/156720; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2018-07-04/000901788.pdf
• topic: Vírus da imunodeficiência felina; Vacinação de animais; Gato; Gammaretrovirus

The Feline viral leukemia, caused by the feline leukemia virus (FeLV), is among the most common infectious diseases of cats leading to immunosuppressive effects. An important prophylactic form for the disease is the vaccination of felines. There are currently several vaccine types available for infection prevention. Vaccines containing the virus inactivated with or without adjuvant (Nobivac®, Merck; Fel-O-Vax®, Fort Dodge; Leukocell-2®, Pfizer; Fevaxyn® FeLV, Schering-Plow; Fel-O-Guard® Plus 4 LV-K, Fort Dodge, Eclipse®4 + FeLV Schering-Plow, Versifel® FeLV, Zoetis), non-adjuvanted canarypox vector viruses (Purevax® and Eurifel®, Merial) and adjuvanted recombinant subunit vaccine (Leucogen®, Virbac). The objective of the present study was to select the types of prophylactic immunization in feline viral leukemia and to evaluate if there is efficacy proven in the literature. We used 14 articles from the PubMed, Science Direct and Google academic databases for this systematic review. The work was classified according to the scales of Jadad et al. (1996) and Cook et al. (1995). Immunization against feline viral leukemia has been shown to be effective in the literature. Thus, the vaccines that obtained the greatest protection against feline leukemia were inactivated, namely Versifel® FeLV, Nobivac®-2-FeLV and Fel-O-Vax®, and inactivated vaccine in combination with the recombinant was also demonstrated quite effective. However, disagreements over the protocol of each study should be taken into account