Ocular melanoma and mammary mucinous carcinoma in an African lion
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1746-6148-8-176 http://hdl.handle.net/11449/12875 |
Resumo: | Background: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.Conclusions: This is the first description of these tumor in African lions. |
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Ocular melanoma and mammary mucinous carcinoma in an African lionPanthera leoOcular neoplasmsMammary glandMelanocytic neoplasmsPeribiliary cystsBackground: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.Conclusions: This is the first description of these tumor in African lions.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Estadual Paulista UNESP, Fac Med Vet & Zootecnia, Dept Clin Vet, Botucatu, SP, BrazilUniv Estadual Paulista UNESP, Fac Med Botucatu, Dept Patol, Botucatu, SP, BrazilFEPI, Curso Med Vet, Itajuba, BrazilPubl Vet Hosp, Dept Diagnost Pathol, Vet Serv, Natl Assoc Small Anim Clinicians Anclivepa, São Paulo, BrazilHosp AC Camargo Fundação Antonio Prudente, Dept Anat Patol, São Paulo, BrazilLouisiana State Univ, Sch Vet Med, Dept Pathobiol Sci, Baton Rouge, LA 70803 USAUniv Estadual Paulista UNESP, Fac Med Vet & Zootecnia, Dept Clin Vet, Botucatu, SP, BrazilUniv Estadual Paulista UNESP, Fac Med Botucatu, Dept Patol, Botucatu, SP, BrazilCNPq: 479178/2010-0FAPESP: 09/53493-9FAPESP: 10/51596-2FAPESP: 11/01610-1Biomed Central Ltd.Universidade Estadual Paulista (Unesp)FEPIPubl Vet HospHosp AC Camargo Fundação Antonio PrudenteLouisiana State UnivCagnini, Didier Quevedo [UNESP]Salgado, Breno S. [UNESP]Linardi, Juliana L. [UNESP]Grandi, Fabrizio [UNESP]Rocha, Rafael M.Rocha, Noeme Sousa [UNESP]Teixeira, Carlos Roberto [UNESP]Del Piero, FabioSequeira, Julio Lopes [UNESP]2014-05-20T13:37:16Z2014-05-20T13:37:16Z2012-09-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5application/pdfhttp://dx.doi.org/10.1186/1746-6148-8-176Bmc Veterinary Research. London: Biomed Central Ltd., v. 8, p. 5, 2012.1746-6148http://hdl.handle.net/11449/1287510.1186/1746-6148-8-176WOS:000312222400001WOS000312222400001.pdf6077735918469284856091313795885034097654240609450000-0002-8188-8149Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBMC Veterinary Research1.9580,934info:eu-repo/semantics/openAccess2024-09-03T13:14:31Zoai:repositorio.unesp.br:11449/12875Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:14:31Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
title |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
spellingShingle |
Ocular melanoma and mammary mucinous carcinoma in an African lion Cagnini, Didier Quevedo [UNESP] Panthera leo Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts |
title_short |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
title_full |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
title_fullStr |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
title_full_unstemmed |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
title_sort |
Ocular melanoma and mammary mucinous carcinoma in an African lion |
author |
Cagnini, Didier Quevedo [UNESP] |
author_facet |
Cagnini, Didier Quevedo [UNESP] Salgado, Breno S. [UNESP] Linardi, Juliana L. [UNESP] Grandi, Fabrizio [UNESP] Rocha, Rafael M. Rocha, Noeme Sousa [UNESP] Teixeira, Carlos Roberto [UNESP] Del Piero, Fabio Sequeira, Julio Lopes [UNESP] |
author_role |
author |
author2 |
Salgado, Breno S. [UNESP] Linardi, Juliana L. [UNESP] Grandi, Fabrizio [UNESP] Rocha, Rafael M. Rocha, Noeme Sousa [UNESP] Teixeira, Carlos Roberto [UNESP] Del Piero, Fabio Sequeira, Julio Lopes [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) FEPI Publ Vet Hosp Hosp AC Camargo Fundação Antonio Prudente Louisiana State Univ |
dc.contributor.author.fl_str_mv |
Cagnini, Didier Quevedo [UNESP] Salgado, Breno S. [UNESP] Linardi, Juliana L. [UNESP] Grandi, Fabrizio [UNESP] Rocha, Rafael M. Rocha, Noeme Sousa [UNESP] Teixeira, Carlos Roberto [UNESP] Del Piero, Fabio Sequeira, Julio Lopes [UNESP] |
dc.subject.por.fl_str_mv |
Panthera leo Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts |
topic |
Panthera leo Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts |
description |
Background: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.Conclusions: This is the first description of these tumor in African lions. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-25 2014-05-20T13:37:16Z 2014-05-20T13:37:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1746-6148-8-176 Bmc Veterinary Research. London: Biomed Central Ltd., v. 8, p. 5, 2012. 1746-6148 http://hdl.handle.net/11449/12875 10.1186/1746-6148-8-176 WOS:000312222400001 WOS000312222400001.pdf 6077735918469284 8560913137958850 3409765424060945 0000-0002-8188-8149 |
url |
http://dx.doi.org/10.1186/1746-6148-8-176 http://hdl.handle.net/11449/12875 |
identifier_str_mv |
Bmc Veterinary Research. London: Biomed Central Ltd., v. 8, p. 5, 2012. 1746-6148 10.1186/1746-6148-8-176 WOS:000312222400001 WOS000312222400001.pdf 6077735918469284 8560913137958850 3409765424060945 0000-0002-8188-8149 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMC Veterinary Research 1.958 0,934 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
5 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021363632570368 |