Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1413-41522018155335 http://hdl.handle.net/11449/170998 |
Resumo: | Pharmaceuticals and endocrine disrupting compounds are found in Brazilian natural waters, including some water sources for public supply, also due to the low coverage of sewage collection and treatment in Brazil. This study investigated the removal of three pharmaceutical compounds — sulfamethoxazole (SMX), diclofenac (DCF) and 17β-estradiol (E2) — from aqueous solutions by means of chlorine oxidation (sodium hypochlorite) by varying the dose of chlorine and contact time in batch tests. The chlorine solutions were examined by chromatography attached to the mass spectrometry in order to identify the oxidation by-products. For 10 min contact time, mean removal values of 61% were observed for DCF; 36% for E2; and 33% for SMX, when the chlorine dose was 1.5 mg L-1. Just for DCF there was a statistically significant difference (α=0.05) in the removal efficiency when increasing the chlorine dose to 3.0 mg.L-1. The oxidation followed the kinetic model of pseudo-second order, with k2 values of 0.0168 L.μg.min-1 for SMX (at both chlorine doses tested); 0.0133 and 0.0798 L.μg.min-1 to DCF; and 0.0326 and 0.0289 L.μg.min-1 to the E2 at chlorine doses of 1.5 and 3.0 mg L-1, respectively. Finally, it was verified that an increase of the contact time favored the oxidation of all pharmaceuticals tested, although with the perspective of by-products formation for SMX and E2. |
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Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scaleOxidação de fármacos por cloro e formação de subprodutos em amostras aquosas em escala de bancadaDisinfectionEndocrine disrupting compoundsOrganic microcontaminantsPharmaceuticalsWater treatmentPharmaceuticals and endocrine disrupting compounds are found in Brazilian natural waters, including some water sources for public supply, also due to the low coverage of sewage collection and treatment in Brazil. This study investigated the removal of three pharmaceutical compounds — sulfamethoxazole (SMX), diclofenac (DCF) and 17β-estradiol (E2) — from aqueous solutions by means of chlorine oxidation (sodium hypochlorite) by varying the dose of chlorine and contact time in batch tests. The chlorine solutions were examined by chromatography attached to the mass spectrometry in order to identify the oxidation by-products. For 10 min contact time, mean removal values of 61% were observed for DCF; 36% for E2; and 33% for SMX, when the chlorine dose was 1.5 mg L-1. Just for DCF there was a statistically significant difference (α=0.05) in the removal efficiency when increasing the chlorine dose to 3.0 mg.L-1. The oxidation followed the kinetic model of pseudo-second order, with k2 values of 0.0168 L.μg.min-1 for SMX (at both chlorine doses tested); 0.0133 and 0.0798 L.μg.min-1 to DCF; and 0.0326 and 0.0289 L.μg.min-1 to the E2 at chlorine doses of 1.5 and 3.0 mg L-1, respectively. Finally, it was verified that an increase of the contact time favored the oxidation of all pharmaceuticals tested, although with the perspective of by-products formation for SMX and E2.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Financiadora de Estudos e ProjetosUniversidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP)Universidade Federal de Ouro Preto (UFOP)Universidade Federal de Minas Gerais (UFMG)Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP)Universidade Estadual Paulista (Unesp)Universidade Federal de Ouro Preto (UFOP)Universidade Federal de Minas Gerais (UFMG)de Souza, Brígida P. [UNESP]Lima, Diego R. S.de Aquino, Sérgio F.Quaresma, Amanda V.Baêta, Bruno E. L.Libânio, Marcelo2018-12-11T16:53:17Z2018-12-11T16:53:17Z2018-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article207-216application/pdfhttp://dx.doi.org/10.1590/S1413-41522018155335Engenharia Sanitaria e Ambiental, v. 23, n. 2, p. 207-216, 2018.1413-4152http://hdl.handle.net/11449/17099810.1590/S1413-41522018155335S1413-415220180002002072-s2.0-85047065018S1413-41522018000200207.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporEngenharia Sanitaria e Ambiental0,218info:eu-repo/semantics/openAccess2023-12-11T06:16:12Zoai:repositorio.unesp.br:11449/170998Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:02:35.982978Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale Oxidação de fármacos por cloro e formação de subprodutos em amostras aquosas em escala de bancada |
title |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
spellingShingle |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale de Souza, Brígida P. [UNESP] Disinfection Endocrine disrupting compounds Organic microcontaminants Pharmaceuticals Water treatment |
title_short |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
title_full |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
title_fullStr |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
title_full_unstemmed |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
title_sort |
Pharmaceuticals oxidation by chlorine and byproducts formation in aqueous matrices in bench scale |
author |
de Souza, Brígida P. [UNESP] |
author_facet |
de Souza, Brígida P. [UNESP] Lima, Diego R. S. de Aquino, Sérgio F. Quaresma, Amanda V. Baêta, Bruno E. L. Libânio, Marcelo |
author_role |
author |
author2 |
Lima, Diego R. S. de Aquino, Sérgio F. Quaresma, Amanda V. Baêta, Bruno E. L. Libânio, Marcelo |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal de Ouro Preto (UFOP) Universidade Federal de Minas Gerais (UFMG) |
dc.contributor.author.fl_str_mv |
de Souza, Brígida P. [UNESP] Lima, Diego R. S. de Aquino, Sérgio F. Quaresma, Amanda V. Baêta, Bruno E. L. Libânio, Marcelo |
dc.subject.por.fl_str_mv |
Disinfection Endocrine disrupting compounds Organic microcontaminants Pharmaceuticals Water treatment |
topic |
Disinfection Endocrine disrupting compounds Organic microcontaminants Pharmaceuticals Water treatment |
description |
Pharmaceuticals and endocrine disrupting compounds are found in Brazilian natural waters, including some water sources for public supply, also due to the low coverage of sewage collection and treatment in Brazil. This study investigated the removal of three pharmaceutical compounds — sulfamethoxazole (SMX), diclofenac (DCF) and 17β-estradiol (E2) — from aqueous solutions by means of chlorine oxidation (sodium hypochlorite) by varying the dose of chlorine and contact time in batch tests. The chlorine solutions were examined by chromatography attached to the mass spectrometry in order to identify the oxidation by-products. For 10 min contact time, mean removal values of 61% were observed for DCF; 36% for E2; and 33% for SMX, when the chlorine dose was 1.5 mg L-1. Just for DCF there was a statistically significant difference (α=0.05) in the removal efficiency when increasing the chlorine dose to 3.0 mg.L-1. The oxidation followed the kinetic model of pseudo-second order, with k2 values of 0.0168 L.μg.min-1 for SMX (at both chlorine doses tested); 0.0133 and 0.0798 L.μg.min-1 to DCF; and 0.0326 and 0.0289 L.μg.min-1 to the E2 at chlorine doses of 1.5 and 3.0 mg L-1, respectively. Finally, it was verified that an increase of the contact time favored the oxidation of all pharmaceuticals tested, although with the perspective of by-products formation for SMX and E2. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-11T16:53:17Z 2018-12-11T16:53:17Z 2018-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1413-41522018155335 Engenharia Sanitaria e Ambiental, v. 23, n. 2, p. 207-216, 2018. 1413-4152 http://hdl.handle.net/11449/170998 10.1590/S1413-41522018155335 S1413-41522018000200207 2-s2.0-85047065018 S1413-41522018000200207.pdf |
url |
http://dx.doi.org/10.1590/S1413-41522018155335 http://hdl.handle.net/11449/170998 |
identifier_str_mv |
Engenharia Sanitaria e Ambiental, v. 23, n. 2, p. 207-216, 2018. 1413-4152 10.1590/S1413-41522018155335 S1413-41522018000200207 2-s2.0-85047065018 S1413-41522018000200207.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Engenharia Sanitaria e Ambiental 0,218 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
207-216 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129153717764096 |