Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/molecules18010244 http://hdl.handle.net/11449/74289 |
Resumo: | A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. © 2013 by the authors. |
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Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activityFlavonoidsMutagenicityNaphthopyranonesPaepalanthusA HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. © 2013 by the authors.Department of Organic Chemistry Institute of Chemistry UNESP - Sao Paulo State University, Araraquara CEP 14800-900, Sao PauloDepartment of Biological Sciences Faculty of Pharmaceutical Sciences of Araraquara UNESP - Sao Paulo State University, Araraquara CEP 14801-902, Sao PauloInstitute of Biosciences Sao Paulo University, Sao Paulo CEP 05508-900, Sao PauloExperimental Campus of Sao Vicente UNESP - Sao Paulo State University, Sao Vicente CEP 11350-000, Sao PauloDepartment of Organic Chemistry Institute of Chemistry UNESP - Sao Paulo State University, Araraquara CEP 14800-900, Sao PauloDepartment of Biological Sciences Faculty of Pharmaceutical Sciences of Araraquara UNESP - Sao Paulo State University, Araraquara CEP 14801-902, Sao PauloExperimental Campus of Sao Vicente UNESP - Sao Paulo State University, Sao Vicente CEP 11350-000, Sao PauloUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Zanutto, Fabiana Volpe [UNESP]Boldrin, Paula Karina [UNESP]Varanda, Eliana Aparecida [UNESP]De Souza, Samara Fernandes [UNESP]Sano, Paulo TakeoVilegas, Wagner [UNESP]Santos, Lourdes Campaner dos [UNESP]2014-05-27T11:27:32Z2014-05-27T11:27:32Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article244-262application/pdfhttp://dx.doi.org/10.3390/molecules18010244Molecules, v. 18, n. 1, p. 244-262, 2013.1420-3049http://hdl.handle.net/11449/7428910.3390/molecules18010244WOS:0003140329000182-s2.0-848728564472-s2.0-848787345902-s2.0-84872856447.pdf792787722432683735382536406029770000-0003-3032-2556Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMolecules3.0980,855info:eu-repo/semantics/openAccess2024-06-24T13:08:26Zoai:repositorio.unesp.br:11449/74289Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-06-24T13:08:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
title |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
spellingShingle |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity Zanutto, Fabiana Volpe [UNESP] Flavonoids Mutagenicity Naphthopyranones Paepalanthus |
title_short |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
title_full |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
title_fullStr |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
title_full_unstemmed |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
title_sort |
Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis herzog by HPLC-ESI-IT-MSn and their mutagenic activity |
author |
Zanutto, Fabiana Volpe [UNESP] |
author_facet |
Zanutto, Fabiana Volpe [UNESP] Boldrin, Paula Karina [UNESP] Varanda, Eliana Aparecida [UNESP] De Souza, Samara Fernandes [UNESP] Sano, Paulo Takeo Vilegas, Wagner [UNESP] Santos, Lourdes Campaner dos [UNESP] |
author_role |
author |
author2 |
Boldrin, Paula Karina [UNESP] Varanda, Eliana Aparecida [UNESP] De Souza, Samara Fernandes [UNESP] Sano, Paulo Takeo Vilegas, Wagner [UNESP] Santos, Lourdes Campaner dos [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Zanutto, Fabiana Volpe [UNESP] Boldrin, Paula Karina [UNESP] Varanda, Eliana Aparecida [UNESP] De Souza, Samara Fernandes [UNESP] Sano, Paulo Takeo Vilegas, Wagner [UNESP] Santos, Lourdes Campaner dos [UNESP] |
dc.subject.por.fl_str_mv |
Flavonoids Mutagenicity Naphthopyranones Paepalanthus |
topic |
Flavonoids Mutagenicity Naphthopyranones Paepalanthus |
description |
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. © 2013 by the authors. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 2014-05-27T11:27:32Z 2014-05-27T11:27:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/molecules18010244 Molecules, v. 18, n. 1, p. 244-262, 2013. 1420-3049 http://hdl.handle.net/11449/74289 10.3390/molecules18010244 WOS:000314032900018 2-s2.0-84872856447 2-s2.0-84878734590 2-s2.0-84872856447.pdf 7927877224326837 3538253640602977 0000-0003-3032-2556 |
url |
http://dx.doi.org/10.3390/molecules18010244 http://hdl.handle.net/11449/74289 |
identifier_str_mv |
Molecules, v. 18, n. 1, p. 244-262, 2013. 1420-3049 10.3390/molecules18010244 WOS:000314032900018 2-s2.0-84872856447 2-s2.0-84878734590 2-s2.0-84872856447.pdf 7927877224326837 3538253640602977 0000-0003-3032-2556 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Molecules 3.098 0,855 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
244-262 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803650297380208640 |