Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.revistas.usp.br/bjvras/article/view/26762 http://hdl.handle.net/11449/71443 |
Resumo: | This work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axis. |
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Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpumReproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruitsFertilityRatReproductive functionSolanum lycocarpumSolasodineSperm productionRattusSolanumThis work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axis.Departamento de Análises Clínicas e Toxicológicas Universidade Federal do Rio Grande do Norte, Natal-RNDepartamento de Morfologia do Instituto de Biociências Universidade Estadual Paulista, Botucatu-SPPatologia Experimental e Comparada Faculdade de Medicina Veterinária e Zootecnia Universidade de São Paulo, São Paulo-SPDepartamento de Patologia Faculdade de Medicina Veterinária e Zootecnia Universidade de São Paulo, São Paulo-SPDepartamento de Morfologia do Instituto de Biociências Universidade Estadual Paulista, Botucatu-SPUniversidade Federal do Rio Grande do Norte (UFRN)Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Schwarz, AlineKempinas, Wilma de Grava [UNESP]Soares, Milena RodriguesBernardi, Maria MarthaSpinosa, Helenice de Souza2014-05-27T11:24:33Z2014-05-27T11:24:33Z2009-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article152-157application/pdfhttp://www.revistas.usp.br/bjvras/article/view/26762Brazilian Journal of Veterinary Research and Animal Science, v. 46, n. 2, p. 152-157, 2009.1413-95961678-4456http://hdl.handle.net/11449/714432-s2.0-781494213162-s2.0-78149421316.pdf6326450271169741Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporBrazilian Journal of Veterinary Research and Animal Science0,2250,225info:eu-repo/semantics/openAccess2024-01-28T06:48:45Zoai:repositorio.unesp.br:11449/71443Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-06T00:08:48.154306Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits |
title |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
spellingShingle |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum Schwarz, Aline Fertility Rat Reproductive function Solanum lycocarpum Solasodine Sperm production Rattus Solanum |
title_short |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
title_full |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
title_fullStr |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
title_full_unstemmed |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
title_sort |
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum |
author |
Schwarz, Aline |
author_facet |
Schwarz, Aline Kempinas, Wilma de Grava [UNESP] Soares, Milena Rodrigues Bernardi, Maria Martha Spinosa, Helenice de Souza |
author_role |
author |
author2 |
Kempinas, Wilma de Grava [UNESP] Soares, Milena Rodrigues Bernardi, Maria Martha Spinosa, Helenice de Souza |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Rio Grande do Norte (UFRN) Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Schwarz, Aline Kempinas, Wilma de Grava [UNESP] Soares, Milena Rodrigues Bernardi, Maria Martha Spinosa, Helenice de Souza |
dc.subject.por.fl_str_mv |
Fertility Rat Reproductive function Solanum lycocarpum Solasodine Sperm production Rattus Solanum |
topic |
Fertility Rat Reproductive function Solanum lycocarpum Solasodine Sperm production Rattus Solanum |
description |
This work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axis. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12-01 2014-05-27T11:24:33Z 2014-05-27T11:24:33Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.revistas.usp.br/bjvras/article/view/26762 Brazilian Journal of Veterinary Research and Animal Science, v. 46, n. 2, p. 152-157, 2009. 1413-9596 1678-4456 http://hdl.handle.net/11449/71443 2-s2.0-78149421316 2-s2.0-78149421316.pdf 6326450271169741 |
url |
http://www.revistas.usp.br/bjvras/article/view/26762 http://hdl.handle.net/11449/71443 |
identifier_str_mv |
Brazilian Journal of Veterinary Research and Animal Science, v. 46, n. 2, p. 152-157, 2009. 1413-9596 1678-4456 2-s2.0-78149421316 2-s2.0-78149421316.pdf 6326450271169741 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science 0,225 0,225 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
152-157 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129589728247808 |