Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2010 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3892/etm_00000033 http://hdl.handle.net/11449/11368 |
Resumo: | Scintimammography using Tc-99m-sestamibi is a noninvasive and painless diagnostic imaging method that is used to detect breast cancer when mammography is inconclusive Because of the advantages of labeling v '7,ith Tc-99m-sestamibi and its high efficiency in detecting carcinomas, it is the most widespread agent for this purpose Its accumulation in the tumor has multifactorial causes and does not depend on the presence of architectural distortion or local or diffuse density variation in the breast The objective of tfiis study was to evaluate the accuracy of scintimammography 1 for detecting breast cancer One hundred and fifty-seven patients presenting 158 palpable and non-palpable breast nodules were evaluated Three patients were male and 154 were female, aged between 14 and 81 years All patients underwent scintimammography, and the nodule was subjected i to cytological or histological study, i e, the gold standard for diagnosing cancer One hundred and eleven malignant and 47 benign nodules were detected, with predominance of ductal carcinomas (n=94) and fibroadenoma/fibrocysiic condition (n=11/n=11), respectively The mean size was 3 11 cm (7-10 cm) among the malignant nodules and 2 07 cm among the benign nodules (0 5-10 cm) The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 89, 89, 95, 78 and 89%, respectively Analysis on the histological types showed that the technique was more effective on tumors that were more aggressive, such as ductal carcinoma In this study, Tc-99m-sestamibi scintim immography was shown to be an important tool for diagnosing breast cancer when mammography was inconclusive |
id |
UNSP_8c6eb637998dcf286d1126edf1987814 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/11368 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosisscintimammographybreast cancerTc-99m-sestamibiScintimammography using Tc-99m-sestamibi is a noninvasive and painless diagnostic imaging method that is used to detect breast cancer when mammography is inconclusive Because of the advantages of labeling v '7,ith Tc-99m-sestamibi and its high efficiency in detecting carcinomas, it is the most widespread agent for this purpose Its accumulation in the tumor has multifactorial causes and does not depend on the presence of architectural distortion or local or diffuse density variation in the breast The objective of tfiis study was to evaluate the accuracy of scintimammography 1 for detecting breast cancer One hundred and fifty-seven patients presenting 158 palpable and non-palpable breast nodules were evaluated Three patients were male and 154 were female, aged between 14 and 81 years All patients underwent scintimammography, and the nodule was subjected i to cytological or histological study, i e, the gold standard for diagnosing cancer One hundred and eleven malignant and 47 benign nodules were detected, with predominance of ductal carcinomas (n=94) and fibroadenoma/fibrocysiic condition (n=11/n=11), respectively The mean size was 3 11 cm (7-10 cm) among the malignant nodules and 2 07 cm among the benign nodules (0 5-10 cm) The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 89, 89, 95, 78 and 89%, respectively Analysis on the histological types showed that the technique was more effective on tumors that were more aggressive, such as ductal carcinoma In this study, Tc-99m-sestamibi scintim immography was shown to be an important tool for diagnosing breast cancer when mammography was inconclusiveBarretos Canc Hosp, Dept Nucl Med, BR-14784400 São Paulo, BrazilSão Paulo State Univ UNESP, Dept Nucl Med, Botucatu Med Sch, BR-18618970 São Paulo, BrazilSão Paulo State Univ UNESP, Dept Obstet & Gynecol, Botucatu Med Sch, BR-18618970 São Paulo, BrazilSão Paulo State Univ UNESP, Dept Nucl Med, Botucatu Med Sch, BR-18618970 São Paulo, BrazilSão Paulo State Univ UNESP, Dept Obstet & Gynecol, Botucatu Med Sch, BR-18618970 São Paulo, BrazilSpandidos Publ LtdBarretos Canc HospUniversidade Estadual Paulista (Unesp)Moriguchi, Sônia Marta [UNESP]De Luca, Laurival Antonio [UNESP]Griva, Beatriz Lotufo [UNESP]Koga, Katia Hiromoto [UNESP]Da Silva, Eduardo TinoisVespoli, Heloísa Maria de Luca [UNESP]Uemura, Gilberto [UNESP]2014-05-20T13:33:15Z2014-05-20T13:33:15Z2010-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article205-209http://dx.doi.org/10.3892/etm_00000033Experimental and Therapeutic Medicine. Athens: Spandidos Publ Ltd, v. 1, n. 1, p. 205-209, 2010.1792-0981http://hdl.handle.net/11449/1136810.3892/etm_00000033WOS:00028456210003398786481435771248550647632202059Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengExperimental and Therapeutic Medicine1.4100,510info:eu-repo/semantics/openAccess2024-08-16T14:12:51Zoai:repositorio.unesp.br:11449/11368Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T14:12:51Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
title |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
spellingShingle |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis Moriguchi, Sônia Marta [UNESP] scintimammography breast cancer Tc-99m-sestamibi |
title_short |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
title_full |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
title_fullStr |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
title_full_unstemmed |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
title_sort |
Accuracy of Tc-99m-sestamibi scintimammography for breast cancer diagnosis |
author |
Moriguchi, Sônia Marta [UNESP] |
author_facet |
Moriguchi, Sônia Marta [UNESP] De Luca, Laurival Antonio [UNESP] Griva, Beatriz Lotufo [UNESP] Koga, Katia Hiromoto [UNESP] Da Silva, Eduardo Tinois Vespoli, Heloísa Maria de Luca [UNESP] Uemura, Gilberto [UNESP] |
author_role |
author |
author2 |
De Luca, Laurival Antonio [UNESP] Griva, Beatriz Lotufo [UNESP] Koga, Katia Hiromoto [UNESP] Da Silva, Eduardo Tinois Vespoli, Heloísa Maria de Luca [UNESP] Uemura, Gilberto [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Barretos Canc Hosp Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Moriguchi, Sônia Marta [UNESP] De Luca, Laurival Antonio [UNESP] Griva, Beatriz Lotufo [UNESP] Koga, Katia Hiromoto [UNESP] Da Silva, Eduardo Tinois Vespoli, Heloísa Maria de Luca [UNESP] Uemura, Gilberto [UNESP] |
dc.subject.por.fl_str_mv |
scintimammography breast cancer Tc-99m-sestamibi |
topic |
scintimammography breast cancer Tc-99m-sestamibi |
description |
Scintimammography using Tc-99m-sestamibi is a noninvasive and painless diagnostic imaging method that is used to detect breast cancer when mammography is inconclusive Because of the advantages of labeling v '7,ith Tc-99m-sestamibi and its high efficiency in detecting carcinomas, it is the most widespread agent for this purpose Its accumulation in the tumor has multifactorial causes and does not depend on the presence of architectural distortion or local or diffuse density variation in the breast The objective of tfiis study was to evaluate the accuracy of scintimammography 1 for detecting breast cancer One hundred and fifty-seven patients presenting 158 palpable and non-palpable breast nodules were evaluated Three patients were male and 154 were female, aged between 14 and 81 years All patients underwent scintimammography, and the nodule was subjected i to cytological or histological study, i e, the gold standard for diagnosing cancer One hundred and eleven malignant and 47 benign nodules were detected, with predominance of ductal carcinomas (n=94) and fibroadenoma/fibrocysiic condition (n=11/n=11), respectively The mean size was 3 11 cm (7-10 cm) among the malignant nodules and 2 07 cm among the benign nodules (0 5-10 cm) The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 89, 89, 95, 78 and 89%, respectively Analysis on the histological types showed that the technique was more effective on tumors that were more aggressive, such as ductal carcinoma In this study, Tc-99m-sestamibi scintim immography was shown to be an important tool for diagnosing breast cancer when mammography was inconclusive |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 2014-05-20T13:33:15Z 2014-05-20T13:33:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3892/etm_00000033 Experimental and Therapeutic Medicine. Athens: Spandidos Publ Ltd, v. 1, n. 1, p. 205-209, 2010. 1792-0981 http://hdl.handle.net/11449/11368 10.3892/etm_00000033 WOS:000284562100033 9878648143577124 8550647632202059 |
url |
http://dx.doi.org/10.3892/etm_00000033 http://hdl.handle.net/11449/11368 |
identifier_str_mv |
Experimental and Therapeutic Medicine. Athens: Spandidos Publ Ltd, v. 1, n. 1, p. 205-209, 2010. 1792-0981 10.3892/etm_00000033 WOS:000284562100033 9878648143577124 8550647632202059 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Experimental and Therapeutic Medicine 1.410 0,510 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
205-209 |
dc.publisher.none.fl_str_mv |
Spandidos Publ Ltd |
publisher.none.fl_str_mv |
Spandidos Publ Ltd |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128199921500160 |