Expressão das caderinas nos tumores mamários em cadelas
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/11533 http://hdl.handle.net/11449/70524 |
Resumo: | Mammary tumors are among the most common neoplasia of canine females. The occurrence of metastasis may be detected by proteic markers. Among them, exist the E-cadherin, a member of cadherin family known for its important role in the regulation of intercellular adhesion in epithelial tissues. Studies suggest that E-cadherin may function as a tumor and invasion suppressor molecule. Cadherin activity is regulated by multiple mechanisms, including interaction with other proteins such as catenins. In this review, the authors approach the cadherin family and other related adhesion proteins including its function, physiopathology and potential use as marker for diagnosis and prognosis of canine mammary tumors. |
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Expressão das caderinas nos tumores mamários em cadelasCadherin expression in canine mammary tumorsCadherinDogImmunohistochemistryMammary neoplasiCanis familiarisMammary tumors are among the most common neoplasia of canine females. The occurrence of metastasis may be detected by proteic markers. Among them, exist the E-cadherin, a member of cadherin family known for its important role in the regulation of intercellular adhesion in epithelial tissues. Studies suggest that E-cadherin may function as a tumor and invasion suppressor molecule. Cadherin activity is regulated by multiple mechanisms, including interaction with other proteins such as catenins. In this review, the authors approach the cadherin family and other related adhesion proteins including its function, physiopathology and potential use as marker for diagnosis and prognosis of canine mammary tumors.Pós-Graduação em Ciências Veterinárias Universidade Federal do Paraná-UFPR, Curitiba, PRDepartamento de Medicina Veterinária UFPR, Curitiba, PRDepartamento de Clínica Veterinária Universidade Estadual Paulista -UNESP, Campus de Botucatu, Botucato, SPDepartamento de Cirurgia e Anestesiologia Veterinária Universidade de Franca -UNIFRAN, Franca, Rua dos Funcionários 1540, 800035-050 Curitiba, PRDepartamento de Clínica Veterinária Universidade Estadual Paulista -UNESP, Campus de Botucatu, Botucato, SPUniversidade Federal do Paraná (UFPR)Universidade Estadual Paulista (Unesp)Universidade de Franca -UNIFRANPiekarz, C. H.Biondo, A. W.Amorim, Renée Laufer [UNESP]Rodaski, S.Barros Filho, Ivan RoqueDe Nardi, A. B.2014-05-27T11:23:38Z2014-05-27T11:23:38Z2008-08-04info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13-21application/pdfhttp://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/11533Archives of Veterinary Science, v. 13, n. 1, p. 13-21, 2008.1517-784Xhttp://hdl.handle.net/11449/705242-s2.0-482491414972-s2.0-48249141497.pdf9795829022108105Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArchives of Veterinary Scienceinfo:eu-repo/semantics/openAccess2023-12-28T06:14:06Zoai:repositorio.unesp.br:11449/70524Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:29:06.642984Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Expressão das caderinas nos tumores mamários em cadelas Cadherin expression in canine mammary tumors |
title |
Expressão das caderinas nos tumores mamários em cadelas |
spellingShingle |
Expressão das caderinas nos tumores mamários em cadelas Piekarz, C. H. Cadherin Dog Immunohistochemistry Mammary neoplasi Canis familiaris |
title_short |
Expressão das caderinas nos tumores mamários em cadelas |
title_full |
Expressão das caderinas nos tumores mamários em cadelas |
title_fullStr |
Expressão das caderinas nos tumores mamários em cadelas |
title_full_unstemmed |
Expressão das caderinas nos tumores mamários em cadelas |
title_sort |
Expressão das caderinas nos tumores mamários em cadelas |
author |
Piekarz, C. H. |
author_facet |
Piekarz, C. H. Biondo, A. W. Amorim, Renée Laufer [UNESP] Rodaski, S. Barros Filho, Ivan Roque De Nardi, A. B. |
author_role |
author |
author2 |
Biondo, A. W. Amorim, Renée Laufer [UNESP] Rodaski, S. Barros Filho, Ivan Roque De Nardi, A. B. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Paraná (UFPR) Universidade Estadual Paulista (Unesp) Universidade de Franca -UNIFRAN |
dc.contributor.author.fl_str_mv |
Piekarz, C. H. Biondo, A. W. Amorim, Renée Laufer [UNESP] Rodaski, S. Barros Filho, Ivan Roque De Nardi, A. B. |
dc.subject.por.fl_str_mv |
Cadherin Dog Immunohistochemistry Mammary neoplasi Canis familiaris |
topic |
Cadherin Dog Immunohistochemistry Mammary neoplasi Canis familiaris |
description |
Mammary tumors are among the most common neoplasia of canine females. The occurrence of metastasis may be detected by proteic markers. Among them, exist the E-cadherin, a member of cadherin family known for its important role in the regulation of intercellular adhesion in epithelial tissues. Studies suggest that E-cadherin may function as a tumor and invasion suppressor molecule. Cadherin activity is regulated by multiple mechanisms, including interaction with other proteins such as catenins. In this review, the authors approach the cadherin family and other related adhesion proteins including its function, physiopathology and potential use as marker for diagnosis and prognosis of canine mammary tumors. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-08-04 2014-05-27T11:23:38Z 2014-05-27T11:23:38Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/11533 Archives of Veterinary Science, v. 13, n. 1, p. 13-21, 2008. 1517-784X http://hdl.handle.net/11449/70524 2-s2.0-48249141497 2-s2.0-48249141497.pdf 9795829022108105 |
url |
http://ojs.c3sl.ufpr.br/ojs/index.php/veterinary/article/view/11533 http://hdl.handle.net/11449/70524 |
identifier_str_mv |
Archives of Veterinary Science, v. 13, n. 1, p. 13-21, 2008. 1517-784X 2-s2.0-48249141497 2-s2.0-48249141497.pdf 9795829022108105 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Archives of Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
13-21 application/pdf |
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Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
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UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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1808129325086539776 |