Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/pharmaceutics13050688 http://hdl.handle.net/11449/207795 |
Resumo: | Treatments of postsurgical dehorning in cattle usually includes topical application of healing agents in wounds. The Bacterial Nanocellulose (BNC) may come to a complementary treatment for these wounds. Two new complementary treatments with BNC and BNC loaded with nisin were evaluated for wound healing in surgical dehorning in bovine. Hence, two groups of experiments were run, and 12 animals were used in each group. All animals, in right and left horns, received antisepsis treatment. For the first group, the left horn was the control, and on the right one the BNC was applied. For the second group, BNC was applied on the left horn (control) and on the right ones BNC+nisin was applied. In both experiments, wounds were evaluated macroscopically by photographic images and microscopically by histology. For macroscopic evaluations, a significant difference was observed over time, but only in the comparison within the same groups. Microscopic analyzes did not showed significant differences in any type of comparison. In conclusion, there was a clinical improvement in the wound healing response with the application of BNC. However, there was no significant difference between BNC compared to the nisin loaded in BNC. For the first time it was applied a BNC in surgical dehorning wounds in bovines and evaluated the efficacy of treatment in a real animal handling situation. |
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Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovinesBacterial nanocelluloseDehorningDressingNisinVeterinary medicinesWound healingTreatments of postsurgical dehorning in cattle usually includes topical application of healing agents in wounds. The Bacterial Nanocellulose (BNC) may come to a complementary treatment for these wounds. Two new complementary treatments with BNC and BNC loaded with nisin were evaluated for wound healing in surgical dehorning in bovine. Hence, two groups of experiments were run, and 12 animals were used in each group. All animals, in right and left horns, received antisepsis treatment. For the first group, the left horn was the control, and on the right one the BNC was applied. For the second group, BNC was applied on the left horn (control) and on the right ones BNC+nisin was applied. In both experiments, wounds were evaluated macroscopically by photographic images and microscopically by histology. For macroscopic evaluations, a significant difference was observed over time, but only in the comparison within the same groups. Microscopic analyzes did not showed significant differences in any type of comparison. In conclusion, there was a clinical improvement in the wound healing response with the application of BNC. However, there was no significant difference between BNC compared to the nisin loaded in BNC. For the first time it was applied a BNC in surgical dehorning wounds in bovines and evaluated the efficacy of treatment in a real animal handling situation.University of SorocabaDepartment of Veterinary Clinical Sciences School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)Department of Veterinary Clinical Sciences School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)University of SorocabaUniversidade Estadual Paulista (Unesp)Custódio, Fábio A. F.de Castro, Leonardo M.Unterkircher, ErickPorto, Ana Carolina R. C.Braga, Iolanda S. [UNESP]Hataka, Alessandre [UNESP]Jozala, Angela F.Grotto, Denise2021-06-25T11:01:06Z2021-06-25T11:01:06Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/pharmaceutics13050688Pharmaceutics, v. 13, n. 5, 2021.1999-4923http://hdl.handle.net/11449/20779510.3390/pharmaceutics130506882-s2.0-85106866589Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPharmaceuticsinfo:eu-repo/semantics/openAccess2021-10-23T17:45:59Zoai:repositorio.unesp.br:11449/207795Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T17:45:59Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
title |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
spellingShingle |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines Custódio, Fábio A. F. Bacterial nanocellulose Dehorning Dressing Nisin Veterinary medicines Wound healing |
title_short |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
title_full |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
title_fullStr |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
title_full_unstemmed |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
title_sort |
Evaluation of bacterial nanocellulose membranes loaded or not with nisin as a complementary treatment in surgical dehorning wounds in bovines |
author |
Custódio, Fábio A. F. |
author_facet |
Custódio, Fábio A. F. de Castro, Leonardo M. Unterkircher, Erick Porto, Ana Carolina R. C. Braga, Iolanda S. [UNESP] Hataka, Alessandre [UNESP] Jozala, Angela F. Grotto, Denise |
author_role |
author |
author2 |
de Castro, Leonardo M. Unterkircher, Erick Porto, Ana Carolina R. C. Braga, Iolanda S. [UNESP] Hataka, Alessandre [UNESP] Jozala, Angela F. Grotto, Denise |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
University of Sorocaba Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Custódio, Fábio A. F. de Castro, Leonardo M. Unterkircher, Erick Porto, Ana Carolina R. C. Braga, Iolanda S. [UNESP] Hataka, Alessandre [UNESP] Jozala, Angela F. Grotto, Denise |
dc.subject.por.fl_str_mv |
Bacterial nanocellulose Dehorning Dressing Nisin Veterinary medicines Wound healing |
topic |
Bacterial nanocellulose Dehorning Dressing Nisin Veterinary medicines Wound healing |
description |
Treatments of postsurgical dehorning in cattle usually includes topical application of healing agents in wounds. The Bacterial Nanocellulose (BNC) may come to a complementary treatment for these wounds. Two new complementary treatments with BNC and BNC loaded with nisin were evaluated for wound healing in surgical dehorning in bovine. Hence, two groups of experiments were run, and 12 animals were used in each group. All animals, in right and left horns, received antisepsis treatment. For the first group, the left horn was the control, and on the right one the BNC was applied. For the second group, BNC was applied on the left horn (control) and on the right ones BNC+nisin was applied. In both experiments, wounds were evaluated macroscopically by photographic images and microscopically by histology. For macroscopic evaluations, a significant difference was observed over time, but only in the comparison within the same groups. Microscopic analyzes did not showed significant differences in any type of comparison. In conclusion, there was a clinical improvement in the wound healing response with the application of BNC. However, there was no significant difference between BNC compared to the nisin loaded in BNC. For the first time it was applied a BNC in surgical dehorning wounds in bovines and evaluated the efficacy of treatment in a real animal handling situation. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T11:01:06Z 2021-06-25T11:01:06Z 2021-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/pharmaceutics13050688 Pharmaceutics, v. 13, n. 5, 2021. 1999-4923 http://hdl.handle.net/11449/207795 10.3390/pharmaceutics13050688 2-s2.0-85106866589 |
url |
http://dx.doi.org/10.3390/pharmaceutics13050688 http://hdl.handle.net/11449/207795 |
identifier_str_mv |
Pharmaceutics, v. 13, n. 5, 2021. 1999-4923 10.3390/pharmaceutics13050688 2-s2.0-85106866589 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Pharmaceutics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964815413739520 |