Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/s19071686 http://hdl.handle.net/11449/190337 |
Resumo: | A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s. |
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Repositório Institucional da UNESP |
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spelling |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detectionBoronic acidElectrochemical Impedance SpectroscopyGlucoseSensorA highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s.Department of Chemical Engineering Universidade Federal de Minas Gerais (UFMG)Center for Optics Photonics and Lasers (COPL) Université LavalCDN IsotopesDepartment of Applied Immunology Fundação Ezequiel Dias (FUNED)Department of Chemistry Universidade Federal de Minas Gerais (UFMG)Institute of Chemistry UNESPInstitute of Chemistry UNESPUniversidade Federal de Minas Gerais (UFMG)Université LavalCDN IsotopesFundação Ezequiel Dias (FUNED)Universidade Estadual Paulista (Unesp)de Faria, Ricardo Adriano DorledoIden, HassanDias Heneine, Luiz GuilhermeMatencio, TulioMessaddeq, Younès [UNESP]2019-10-06T17:09:51Z2019-10-06T17:09:51Z2019-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/s19071686Sensors (Switzerland), v. 19, n. 7, 2019.1424-8220http://hdl.handle.net/11449/19033710.3390/s190716862-s2.0-85065777716Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSensors (Switzerland)info:eu-repo/semantics/openAccess2021-10-23T02:05:50Zoai:repositorio.unesp.br:11449/190337Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:18:35.469387Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
title |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
spellingShingle |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection de Faria, Ricardo Adriano Dorledo Boronic acid Electrochemical Impedance Spectroscopy Glucose Sensor |
title_short |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
title_full |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
title_fullStr |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
title_full_unstemmed |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
title_sort |
Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection |
author |
de Faria, Ricardo Adriano Dorledo |
author_facet |
de Faria, Ricardo Adriano Dorledo Iden, Hassan Dias Heneine, Luiz Guilherme Matencio, Tulio Messaddeq, Younès [UNESP] |
author_role |
author |
author2 |
Iden, Hassan Dias Heneine, Luiz Guilherme Matencio, Tulio Messaddeq, Younès [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Minas Gerais (UFMG) Université Laval CDN Isotopes Fundação Ezequiel Dias (FUNED) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
de Faria, Ricardo Adriano Dorledo Iden, Hassan Dias Heneine, Luiz Guilherme Matencio, Tulio Messaddeq, Younès [UNESP] |
dc.subject.por.fl_str_mv |
Boronic acid Electrochemical Impedance Spectroscopy Glucose Sensor |
topic |
Boronic acid Electrochemical Impedance Spectroscopy Glucose Sensor |
description |
A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T17:09:51Z 2019-10-06T17:09:51Z 2019-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/s19071686 Sensors (Switzerland), v. 19, n. 7, 2019. 1424-8220 http://hdl.handle.net/11449/190337 10.3390/s19071686 2-s2.0-85065777716 |
url |
http://dx.doi.org/10.3390/s19071686 http://hdl.handle.net/11449/190337 |
identifier_str_mv |
Sensors (Switzerland), v. 19, n. 7, 2019. 1424-8220 10.3390/s19071686 2-s2.0-85065777716 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Sensors (Switzerland) |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129505951219712 |