Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection

Detalhes bibliográficos
Autor(a) principal: de Faria, Ricardo Adriano Dorledo
Data de Publicação: 2019
Outros Autores: Iden, Hassan, Dias Heneine, Luiz Guilherme, Matencio, Tulio, Messaddeq, Younès [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/s19071686
http://hdl.handle.net/11449/190337
Resumo: A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s.
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spelling Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detectionBoronic acidElectrochemical Impedance SpectroscopyGlucoseSensorA highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s.Department of Chemical Engineering Universidade Federal de Minas Gerais (UFMG)Center for Optics Photonics and Lasers (COPL) Université LavalCDN IsotopesDepartment of Applied Immunology Fundação Ezequiel Dias (FUNED)Department of Chemistry Universidade Federal de Minas Gerais (UFMG)Institute of Chemistry UNESPInstitute of Chemistry UNESPUniversidade Federal de Minas Gerais (UFMG)Université LavalCDN IsotopesFundação Ezequiel Dias (FUNED)Universidade Estadual Paulista (Unesp)de Faria, Ricardo Adriano DorledoIden, HassanDias Heneine, Luiz GuilhermeMatencio, TulioMessaddeq, Younès [UNESP]2019-10-06T17:09:51Z2019-10-06T17:09:51Z2019-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/s19071686Sensors (Switzerland), v. 19, n. 7, 2019.1424-8220http://hdl.handle.net/11449/19033710.3390/s190716862-s2.0-85065777716Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSensors (Switzerland)info:eu-repo/semantics/openAccess2021-10-23T02:05:50Zoai:repositorio.unesp.br:11449/190337Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:18:35.469387Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
title Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
spellingShingle Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
de Faria, Ricardo Adriano Dorledo
Boronic acid
Electrochemical Impedance Spectroscopy
Glucose
Sensor
title_short Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
title_full Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
title_fullStr Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
title_full_unstemmed Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
title_sort Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
author de Faria, Ricardo Adriano Dorledo
author_facet de Faria, Ricardo Adriano Dorledo
Iden, Hassan
Dias Heneine, Luiz Guilherme
Matencio, Tulio
Messaddeq, Younès [UNESP]
author_role author
author2 Iden, Hassan
Dias Heneine, Luiz Guilherme
Matencio, Tulio
Messaddeq, Younès [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Minas Gerais (UFMG)
Université Laval
CDN Isotopes
Fundação Ezequiel Dias (FUNED)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv de Faria, Ricardo Adriano Dorledo
Iden, Hassan
Dias Heneine, Luiz Guilherme
Matencio, Tulio
Messaddeq, Younès [UNESP]
dc.subject.por.fl_str_mv Boronic acid
Electrochemical Impedance Spectroscopy
Glucose
Sensor
topic Boronic acid
Electrochemical Impedance Spectroscopy
Glucose
Sensor
description A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-06T17:09:51Z
2019-10-06T17:09:51Z
2019-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/s19071686
Sensors (Switzerland), v. 19, n. 7, 2019.
1424-8220
http://hdl.handle.net/11449/190337
10.3390/s19071686
2-s2.0-85065777716
url http://dx.doi.org/10.3390/s19071686
http://hdl.handle.net/11449/190337
identifier_str_mv Sensors (Switzerland), v. 19, n. 7, 2019.
1424-8220
10.3390/s19071686
2-s2.0-85065777716
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sensors (Switzerland)
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129505951219712