Genomic analysis on Brazilian strains of Anaplasma marginale

Detalhes bibliográficos
Autor(a) principal: Dall'Agnol, Bruno
Data de Publicação: 2021
Outros Autores: Webster, Anelise, Souza, Ugo Araújo, Barbieri, Antonela, Mayer, Fabiana Quoos, Cardoso, Gisele Antoniazzi, Torres, Tatiana Teixeira, Machado, Rosangela Zacarias [UNESP], Ferreira, Carlos Alexandre Sanchez, Reck, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1984-29612021043
http://hdl.handle.net/11449/208743
Resumo: Anaplasma marginale is a vector-borne pathogen that causes a disease known as anaplasmosis. No sequenced genomes of Brazilian strains are yet available. The aim of this work was to compare whole genomes of Brazilian strains of A. marginale (Palmeira and Jaboticabal) with genomes of strains from other regions (USA and Australia strains). Genome sequencing of Brazilian strains was performed by means of next-generation sequencing. Reads were mapped using the genome of the Florida strain of A. marginale as a reference sequence. Single nucleotide polymorphisms (SNPs) and insertions/deletions (INDELs) were identified. The data showed that two Brazilian strains grouped together in one particular clade, which grouped in a larger American group together with North American strains. Moreover, some important differences in surface proteins between the two Brazilian isolates can be discerned. These results shed light on the evolutionary history of A. marginale and provide the first genome information on South American isolates. Assessing the genome sequences of strains from different regions is essential for increasing knowledge of the pan-genome of this bacteria.
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spelling Genomic analysis on Brazilian strains of Anaplasma marginaleAnaplasma marginale is a vector-borne pathogen that causes a disease known as anaplasmosis. No sequenced genomes of Brazilian strains are yet available. The aim of this work was to compare whole genomes of Brazilian strains of A. marginale (Palmeira and Jaboticabal) with genomes of strains from other regions (USA and Australia strains). Genome sequencing of Brazilian strains was performed by means of next-generation sequencing. Reads were mapped using the genome of the Florida strain of A. marginale as a reference sequence. Single nucleotide polymorphisms (SNPs) and insertions/deletions (INDELs) were identified. The data showed that two Brazilian strains grouped together in one particular clade, which grouped in a larger American group together with North American strains. Moreover, some important differences in surface proteins between the two Brazilian isolates can be discerned. These results shed light on the evolutionary history of A. marginale and provide the first genome information on South American isolates. Assessing the genome sequences of strains from different regions is essential for increasing knowledge of the pan-genome of this bacteria.Centro de Pesquisa em Saúde Animal Instituto de Pesquisas Veterinárias Desidério Finamor - IPVDF RSInstituto de Biociências Universidade de São Paulo - USPFaculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista - UNESPEscola de Ciências da Saúde e da Vida Pontifícia Universidade Católica do Rio Grande do Sul - PUCRS RSFaculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista - UNESPRSUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Dall'Agnol, BrunoWebster, AneliseSouza, Ugo AraújoBarbieri, AntonelaMayer, Fabiana QuoosCardoso, Gisele AntoniazziTorres, Tatiana TeixeiraMachado, Rosangela Zacarias [UNESP]Ferreira, Carlos Alexandre SanchezReck, José2021-06-25T11:18:16Z2021-06-25T11:18:16Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlee000421application/pdfhttp://dx.doi.org/10.1590/S1984-29612021043Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, v. 30, n. 2, p. e000421-, 2021.1984-2961http://hdl.handle.net/11449/20874310.1590/S1984-29612021043S1984-296120210002003102-s2.0-85107441758S1984-29612021000200310.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinariainfo:eu-repo/semantics/openAccess2024-06-07T13:02:57Zoai:repositorio.unesp.br:11449/208743Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:40:37.157354Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Genomic analysis on Brazilian strains of Anaplasma marginale
title Genomic analysis on Brazilian strains of Anaplasma marginale
spellingShingle Genomic analysis on Brazilian strains of Anaplasma marginale
Dall'Agnol, Bruno
title_short Genomic analysis on Brazilian strains of Anaplasma marginale
title_full Genomic analysis on Brazilian strains of Anaplasma marginale
title_fullStr Genomic analysis on Brazilian strains of Anaplasma marginale
title_full_unstemmed Genomic analysis on Brazilian strains of Anaplasma marginale
title_sort Genomic analysis on Brazilian strains of Anaplasma marginale
author Dall'Agnol, Bruno
author_facet Dall'Agnol, Bruno
Webster, Anelise
Souza, Ugo Araújo
Barbieri, Antonela
Mayer, Fabiana Quoos
Cardoso, Gisele Antoniazzi
Torres, Tatiana Teixeira
Machado, Rosangela Zacarias [UNESP]
Ferreira, Carlos Alexandre Sanchez
Reck, José
author_role author
author2 Webster, Anelise
Souza, Ugo Araújo
Barbieri, Antonela
Mayer, Fabiana Quoos
Cardoso, Gisele Antoniazzi
Torres, Tatiana Teixeira
Machado, Rosangela Zacarias [UNESP]
Ferreira, Carlos Alexandre Sanchez
Reck, José
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RS
Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Dall'Agnol, Bruno
Webster, Anelise
Souza, Ugo Araújo
Barbieri, Antonela
Mayer, Fabiana Quoos
Cardoso, Gisele Antoniazzi
Torres, Tatiana Teixeira
Machado, Rosangela Zacarias [UNESP]
Ferreira, Carlos Alexandre Sanchez
Reck, José
description Anaplasma marginale is a vector-borne pathogen that causes a disease known as anaplasmosis. No sequenced genomes of Brazilian strains are yet available. The aim of this work was to compare whole genomes of Brazilian strains of A. marginale (Palmeira and Jaboticabal) with genomes of strains from other regions (USA and Australia strains). Genome sequencing of Brazilian strains was performed by means of next-generation sequencing. Reads were mapped using the genome of the Florida strain of A. marginale as a reference sequence. Single nucleotide polymorphisms (SNPs) and insertions/deletions (INDELs) were identified. The data showed that two Brazilian strains grouped together in one particular clade, which grouped in a larger American group together with North American strains. Moreover, some important differences in surface proteins between the two Brazilian isolates can be discerned. These results shed light on the evolutionary history of A. marginale and provide the first genome information on South American isolates. Assessing the genome sequences of strains from different regions is essential for increasing knowledge of the pan-genome of this bacteria.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T11:18:16Z
2021-06-25T11:18:16Z
2021-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1984-29612021043
Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, v. 30, n. 2, p. e000421-, 2021.
1984-2961
http://hdl.handle.net/11449/208743
10.1590/S1984-29612021043
S1984-29612021000200310
2-s2.0-85107441758
S1984-29612021000200310.pdf
url http://dx.doi.org/10.1590/S1984-29612021043
http://hdl.handle.net/11449/208743
identifier_str_mv Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, v. 30, n. 2, p. e000421-, 2021.
1984-2961
10.1590/S1984-29612021043
S1984-29612021000200310
2-s2.0-85107441758
S1984-29612021000200310.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv e000421
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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