Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

Detalhes bibliográficos
Autor(a) principal: Shiroma, Letícia Sayuri
Data de Publicação: 2020
Outros Autores: Soares, Michelly Pereira [UNESP], Cardoso, Israel Luz [UNESP], Ishikawa, Marcia Mayumi, Jonsson, Claudio Martin, Nascimento Queiroz, Sonia Claudia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.heliyon.2020.e05716
http://hdl.handle.net/11449/206983
Resumo: Antibiotics, Hematological Variables, Oxidative stress, Aquaculture; Agricultural Water Management; Environmental Science; Environmental Risk Assessment; Environmental Toxicology; Toxicology
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spelling Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicolAgricultural water managementAntibioticsAquacultureEnvironmental risk assessmentEnvironmental scienceEnvironmental toxicologyHematological variablesOxidative stressToxicologyAntibiotics, Hematological Variables, Oxidative stress, Aquaculture; Agricultural Water Management; Environmental Science; Environmental Risk Assessment; Environmental Toxicology; ToxicologyIntensive fish cultivation has a high incidence of infection, which is often controlled by administering antibiotics. Florfenicol (FF) is one of the two antimicrobial drugs permitted for aquaculture in Brazil. Due to their intensive use, potentially harmful effects on aquatic organisms are of great concern. In this sense, we investigated whether the presence of FF in cultivation water could change the health parameters of Nile tilapia. For this, we evaluated hemoglobin, hematocrit, mean corpuscular hemoglobin (MCHC) concentration, mean corpuscular volume (MCV), total plasma protein (TPP), number of circulating red blood cells and leukocytes, as lipid peroxidation levels, catalase activity and glutathione S-transferase activity of fish exposed to 11.72 mg L−1 of FF in water for 48 h. The fish were divided into two groups: Nile tilapia in water with FF or without FF (control). Exposure to FF in cultivation water for a short period didn't change the hematological variables analyzed, but caused changes in liver ROS (Reactive oxygen species) markers of the Nile tilapia, which was revealed by lipid peroxidation levels, catalase activity, and glutathione S-transferase. The 48h exposure period was enough to induce oxidative stress in hepatocytes, causing cellular oxidative damage. Therefore, the antibiotic florfenicol may cause toxicity to organisms and aquatic ecosystems, even at a sublethal concentrations near 1/100 LC50-48h for fish species.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Empresa Brasileira de Pesquisa AgropecuáriaInstitute of Chemistry University of Campinas, POB 6154Joint Graduate Program in Physiological Sciences Federal University of São Carlos -UFSCar/São Paulo State University UNESP Campus AraraquaraEmbrapa Environment Brazilian Agricultural Research Corporation (EMBRAPA), Rod. SP 340, Km 127,5, Caixa Postal 69Joint Graduate Program in Physiological Sciences Federal University of São Carlos -UFSCar/São Paulo State University UNESP Campus AraraquaraEmpresa Brasileira de Pesquisa Agropecuária: 0117020010606007Universidade Estadual de Campinas (UNICAMP)Universidade Estadual Paulista (Unesp)Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Shiroma, Letícia SayuriSoares, Michelly Pereira [UNESP]Cardoso, Israel Luz [UNESP]Ishikawa, Marcia MayumiJonsson, Claudio MartinNascimento Queiroz, Sonia Claudia2021-06-25T10:47:06Z2021-06-25T10:47:06Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.heliyon.2020.e05716Heliyon, v. 6, n. 12, 2020.2405-8440http://hdl.handle.net/11449/20698310.1016/j.heliyon.2020.e057162-s2.0-85097733841Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengHeliyoninfo:eu-repo/semantics/openAccess2021-10-23T15:55:00Zoai:repositorio.unesp.br:11449/206983Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T15:55Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
title Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
spellingShingle Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
Shiroma, Letícia Sayuri
Agricultural water management
Antibiotics
Aquaculture
Environmental risk assessment
Environmental science
Environmental toxicology
Hematological variables
Oxidative stress
Toxicology
title_short Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
title_full Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
title_fullStr Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
title_full_unstemmed Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
title_sort Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol
author Shiroma, Letícia Sayuri
author_facet Shiroma, Letícia Sayuri
Soares, Michelly Pereira [UNESP]
Cardoso, Israel Luz [UNESP]
Ishikawa, Marcia Mayumi
Jonsson, Claudio Martin
Nascimento Queiroz, Sonia Claudia
author_role author
author2 Soares, Michelly Pereira [UNESP]
Cardoso, Israel Luz [UNESP]
Ishikawa, Marcia Mayumi
Jonsson, Claudio Martin
Nascimento Queiroz, Sonia Claudia
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual Paulista (Unesp)
Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.author.fl_str_mv Shiroma, Letícia Sayuri
Soares, Michelly Pereira [UNESP]
Cardoso, Israel Luz [UNESP]
Ishikawa, Marcia Mayumi
Jonsson, Claudio Martin
Nascimento Queiroz, Sonia Claudia
dc.subject.por.fl_str_mv Agricultural water management
Antibiotics
Aquaculture
Environmental risk assessment
Environmental science
Environmental toxicology
Hematological variables
Oxidative stress
Toxicology
topic Agricultural water management
Antibiotics
Aquaculture
Environmental risk assessment
Environmental science
Environmental toxicology
Hematological variables
Oxidative stress
Toxicology
description Antibiotics, Hematological Variables, Oxidative stress, Aquaculture; Agricultural Water Management; Environmental Science; Environmental Risk Assessment; Environmental Toxicology; Toxicology
publishDate 2020
dc.date.none.fl_str_mv 2020-12-01
2021-06-25T10:47:06Z
2021-06-25T10:47:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.heliyon.2020.e05716
Heliyon, v. 6, n. 12, 2020.
2405-8440
http://hdl.handle.net/11449/206983
10.1016/j.heliyon.2020.e05716
2-s2.0-85097733841
url http://dx.doi.org/10.1016/j.heliyon.2020.e05716
http://hdl.handle.net/11449/206983
identifier_str_mv Heliyon, v. 6, n. 12, 2020.
2405-8440
10.1016/j.heliyon.2020.e05716
2-s2.0-85097733841
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Heliyon
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964922209107968

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