Immunophenotyping of thymic lymphoma in a Nelore cow
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-21-20881_2012_8_18_27_4.pdf http://hdl.handle.net/11449/73420 |
Resumo: | Thymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive. |
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Repositório Institucional da UNESP |
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spelling |
Immunophenotyping of thymic lymphoma in a Nelore cowCD8 T cellImmunohistochemistryNelore breedThymic lymphomaThymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive.FCAV - Unesp/JaboticabalFCAV - Unesp/JaboticabalUniversidade Estadual Paulista (Unesp)Sampaio, Paulo H. [UNESP]Fidelis Jr., Otávio L. [UNESP]de Queiroz, Daniela J. [UNESP]Soares, Luciana M.C. [UNESP]Moreira, Pamela R.R. [UNESP]Vasconcelos, Rosemeri O. [UNESP]Marques, Luiz C. [UNESP]Alessi, Antonio C. [UNESP]2014-05-27T11:26:52Z2014-05-27T11:26:52Z2012-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article94-98http://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-21-20881_2012_8_18_27_4.pdfBrazilian Journal of Veterinary Pathology, v. 5, n. 2, p. 94-98, 2012.1983-0246http://hdl.handle.net/11449/734202-s2.0-84864846862Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Veterinary Pathology0,162info:eu-repo/semantics/openAccess2021-10-23T10:45:09Zoai:repositorio.unesp.br:11449/73420Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T10:45:09Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Immunophenotyping of thymic lymphoma in a Nelore cow |
title |
Immunophenotyping of thymic lymphoma in a Nelore cow |
spellingShingle |
Immunophenotyping of thymic lymphoma in a Nelore cow Sampaio, Paulo H. [UNESP] CD8 T cell Immunohistochemistry Nelore breed Thymic lymphoma |
title_short |
Immunophenotyping of thymic lymphoma in a Nelore cow |
title_full |
Immunophenotyping of thymic lymphoma in a Nelore cow |
title_fullStr |
Immunophenotyping of thymic lymphoma in a Nelore cow |
title_full_unstemmed |
Immunophenotyping of thymic lymphoma in a Nelore cow |
title_sort |
Immunophenotyping of thymic lymphoma in a Nelore cow |
author |
Sampaio, Paulo H. [UNESP] |
author_facet |
Sampaio, Paulo H. [UNESP] Fidelis Jr., Otávio L. [UNESP] de Queiroz, Daniela J. [UNESP] Soares, Luciana M.C. [UNESP] Moreira, Pamela R.R. [UNESP] Vasconcelos, Rosemeri O. [UNESP] Marques, Luiz C. [UNESP] Alessi, Antonio C. [UNESP] |
author_role |
author |
author2 |
Fidelis Jr., Otávio L. [UNESP] de Queiroz, Daniela J. [UNESP] Soares, Luciana M.C. [UNESP] Moreira, Pamela R.R. [UNESP] Vasconcelos, Rosemeri O. [UNESP] Marques, Luiz C. [UNESP] Alessi, Antonio C. [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Sampaio, Paulo H. [UNESP] Fidelis Jr., Otávio L. [UNESP] de Queiroz, Daniela J. [UNESP] Soares, Luciana M.C. [UNESP] Moreira, Pamela R.R. [UNESP] Vasconcelos, Rosemeri O. [UNESP] Marques, Luiz C. [UNESP] Alessi, Antonio C. [UNESP] |
dc.subject.por.fl_str_mv |
CD8 T cell Immunohistochemistry Nelore breed Thymic lymphoma |
topic |
CD8 T cell Immunohistochemistry Nelore breed Thymic lymphoma |
description |
Thymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-07-01 2014-05-27T11:26:52Z 2014-05-27T11:26:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-21-20881_2012_8_18_27_4.pdf Brazilian Journal of Veterinary Pathology, v. 5, n. 2, p. 94-98, 2012. 1983-0246 http://hdl.handle.net/11449/73420 2-s2.0-84864846862 |
url |
http://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-21-20881_2012_8_18_27_4.pdf http://hdl.handle.net/11449/73420 |
identifier_str_mv |
Brazilian Journal of Veterinary Pathology, v. 5, n. 2, p. 94-98, 2012. 1983-0246 2-s2.0-84864846862 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Veterinary Pathology 0,162 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
94-98 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964380987654144 |