In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry

Detalhes bibliográficos
Autor(a) principal: Fonseca-Alves, Carlos E. [UNESP]
Data de Publicação: 2022
Outros Autores: Lainetti, Patrícia de F. [UNESP]
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/978-1-0716-2403-6_8
http://hdl.handle.net/11449/240402
Resumo: The vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model.
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spelling In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic MimicryAnticancer compoundsCancer cellVascular-like channelsVasculogenicXenograft modelThe vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model.School of Veterinary Medicine and Animal Science Sao Paulo State University – UNESPInstitute of Animal Health Universidade Paulista-UNIPSchool of Veterinary Medicine and Animal Science Sao Paulo State University – UNESPUniversidade Estadual Paulista (UNESP)Universidade Paulista-UNIPFonseca-Alves, Carlos E. [UNESP]Lainetti, Patrícia de F. [UNESP]2023-03-01T20:15:27Z2023-03-01T20:15:27Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart75-84http://dx.doi.org/10.1007/978-1-0716-2403-6_8Methods in Molecular Biology, v. 2514, p. 75-84.1940-60291064-3745http://hdl.handle.net/11449/24040210.1007/978-1-0716-2403-6_82-s2.0-85133499310Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMethods in Molecular Biologyinfo:eu-repo/semantics/openAccess2023-03-01T20:15:27Zoai:repositorio.unesp.br:11449/240402Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:47:13.931429Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
title In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
spellingShingle In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
Fonseca-Alves, Carlos E. [UNESP]
Anticancer compounds
Cancer cell
Vascular-like channels
Vasculogenic
Xenograft model
title_short In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
title_full In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
title_fullStr In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
title_full_unstemmed In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
title_sort In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
author Fonseca-Alves, Carlos E. [UNESP]
author_facet Fonseca-Alves, Carlos E. [UNESP]
Lainetti, Patrícia de F. [UNESP]
author_role author
author2 Lainetti, Patrícia de F. [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidade Paulista-UNIP
dc.contributor.author.fl_str_mv Fonseca-Alves, Carlos E. [UNESP]
Lainetti, Patrícia de F. [UNESP]
dc.subject.por.fl_str_mv Anticancer compounds
Cancer cell
Vascular-like channels
Vasculogenic
Xenograft model
topic Anticancer compounds
Cancer cell
Vascular-like channels
Vasculogenic
Xenograft model
description The vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
2023-03-01T20:15:27Z
2023-03-01T20:15:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/978-1-0716-2403-6_8
Methods in Molecular Biology, v. 2514, p. 75-84.
1940-6029
1064-3745
http://hdl.handle.net/11449/240402
10.1007/978-1-0716-2403-6_8
2-s2.0-85133499310
url http://dx.doi.org/10.1007/978-1-0716-2403-6_8
http://hdl.handle.net/11449/240402
identifier_str_mv Methods in Molecular Biology, v. 2514, p. 75-84.
1940-6029
1064-3745
10.1007/978-1-0716-2403-6_8
2-s2.0-85133499310
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Methods in Molecular Biology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 75-84
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128700812623872

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