In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | |
Tipo de documento: | Capítulo de livro |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/978-1-0716-2403-6_8 http://hdl.handle.net/11449/240402 |
Resumo: | The vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model. |
id |
UNSP_9d1ccd3ebab7447b9947393025c243a8 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/240402 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic MimicryAnticancer compoundsCancer cellVascular-like channelsVasculogenicXenograft modelThe vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model.School of Veterinary Medicine and Animal Science Sao Paulo State University – UNESPInstitute of Animal Health Universidade Paulista-UNIPSchool of Veterinary Medicine and Animal Science Sao Paulo State University – UNESPUniversidade Estadual Paulista (UNESP)Universidade Paulista-UNIPFonseca-Alves, Carlos E. [UNESP]Lainetti, Patrícia de F. [UNESP]2023-03-01T20:15:27Z2023-03-01T20:15:27Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart75-84http://dx.doi.org/10.1007/978-1-0716-2403-6_8Methods in Molecular Biology, v. 2514, p. 75-84.1940-60291064-3745http://hdl.handle.net/11449/24040210.1007/978-1-0716-2403-6_82-s2.0-85133499310Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMethods in Molecular Biologyinfo:eu-repo/semantics/openAccess2023-03-01T20:15:27Zoai:repositorio.unesp.br:11449/240402Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:47:13.931429Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
title |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
spellingShingle |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry Fonseca-Alves, Carlos E. [UNESP] Anticancer compounds Cancer cell Vascular-like channels Vasculogenic Xenograft model |
title_short |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
title_full |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
title_fullStr |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
title_full_unstemmed |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
title_sort |
In Vivo Models to Evaluate Antitumor Drugs Effect on Vasculogenic Mimicry |
author |
Fonseca-Alves, Carlos E. [UNESP] |
author_facet |
Fonseca-Alves, Carlos E. [UNESP] Lainetti, Patrícia de F. [UNESP] |
author_role |
author |
author2 |
Lainetti, Patrícia de F. [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade Paulista-UNIP |
dc.contributor.author.fl_str_mv |
Fonseca-Alves, Carlos E. [UNESP] Lainetti, Patrícia de F. [UNESP] |
dc.subject.por.fl_str_mv |
Anticancer compounds Cancer cell Vascular-like channels Vasculogenic Xenograft model |
topic |
Anticancer compounds Cancer cell Vascular-like channels Vasculogenic Xenograft model |
description |
The vasculogenic mimicry (VM) in vivo evaluation is challenging, and new models have been proposed to evaluate antitumor effect of different compounds using in vivo models. However, there is no gold standard in vivo models established for VM evaluation. As occurs for other in vivo tumor analysis, the use of immunodeficient mouse model and cell line with in vivo tumorigenicity and ability to induce vasculogenic mimicry is the most used model. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 2023-03-01T20:15:27Z 2023-03-01T20:15:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bookPart |
format |
bookPart |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/978-1-0716-2403-6_8 Methods in Molecular Biology, v. 2514, p. 75-84. 1940-6029 1064-3745 http://hdl.handle.net/11449/240402 10.1007/978-1-0716-2403-6_8 2-s2.0-85133499310 |
url |
http://dx.doi.org/10.1007/978-1-0716-2403-6_8 http://hdl.handle.net/11449/240402 |
identifier_str_mv |
Methods in Molecular Biology, v. 2514, p. 75-84. 1940-6029 1064-3745 10.1007/978-1-0716-2403-6_8 2-s2.0-85133499310 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Methods in Molecular Biology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
75-84 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128700812623872 |