Zein nanoparticles and strategies to improve colloidal stability: A mini-review
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3389/fchem.2018.00006 http://hdl.handle.net/11449/179591 |
Resumo: | Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture. |
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Zein nanoparticles and strategies to improve colloidal stability: A mini-reviewColloidal stabilityIonic strengthNanoparticlesThermal treatmentZeinZein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture.Environmental Chemistry Institute of Science and Technology São Paulo State University (UNESP)Department of Biotechnology University of SorocabaEnvironmental Chemistry Institute of Science and Technology São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)University of SorocabaPascoli, Mônica [UNESP]de Lima, RenataFraceto, Leonardo F. [UNESP]2018-12-11T17:35:57Z2018-12-11T17:35:57Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.3389/fchem.2018.00006Frontiers in Chemistry, v. 6, n. JAN, 2018.2296-2646http://hdl.handle.net/11449/17959110.3389/fchem.2018.000062-s2.0-850421153612-s2.0-85042115361.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Chemistry1,352info:eu-repo/semantics/openAccess2023-12-03T06:11:09Zoai:repositorio.unesp.br:11449/179591Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:21:31.486398Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
title |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
spellingShingle |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review Pascoli, Mônica [UNESP] Colloidal stability Ionic strength Nanoparticles Thermal treatment Zein |
title_short |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
title_full |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
title_fullStr |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
title_full_unstemmed |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
title_sort |
Zein nanoparticles and strategies to improve colloidal stability: A mini-review |
author |
Pascoli, Mônica [UNESP] |
author_facet |
Pascoli, Mônica [UNESP] de Lima, Renata Fraceto, Leonardo F. [UNESP] |
author_role |
author |
author2 |
de Lima, Renata Fraceto, Leonardo F. [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Sorocaba |
dc.contributor.author.fl_str_mv |
Pascoli, Mônica [UNESP] de Lima, Renata Fraceto, Leonardo F. [UNESP] |
dc.subject.por.fl_str_mv |
Colloidal stability Ionic strength Nanoparticles Thermal treatment Zein |
topic |
Colloidal stability Ionic strength Nanoparticles Thermal treatment Zein |
description |
Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-11T17:35:57Z 2018-12-11T17:35:57Z 2018-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3389/fchem.2018.00006 Frontiers in Chemistry, v. 6, n. JAN, 2018. 2296-2646 http://hdl.handle.net/11449/179591 10.3389/fchem.2018.00006 2-s2.0-85042115361 2-s2.0-85042115361.pdf |
url |
http://dx.doi.org/10.3389/fchem.2018.00006 http://hdl.handle.net/11449/179591 |
identifier_str_mv |
Frontiers in Chemistry, v. 6, n. JAN, 2018. 2296-2646 10.3389/fchem.2018.00006 2-s2.0-85042115361 2-s2.0-85042115361.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Frontiers in Chemistry 1,352 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129057304346624 |