Addressing the COVID-19 transmission in inner Brazil by a mathematical model

Detalhes bibliográficos
Autor(a) principal: Almeida, G. B. [UNESP]
Data de Publicação: 2021
Outros Autores: Vilches, T. N., Ferreira, C. P. [UNESP], Fortaleza, C. M.C.B. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1038/s41598-021-90118-5
http://hdl.handle.net/11449/221759
Resumo: In 2020, the world experienced its very first pandemic of the globalized era. A novel coronavirus, SARS-CoV-2, is the causative agent of severe pneumonia and has rapidly spread through many nations, crashing health systems and leading a large number of people to death. In Brazil, the emergence of local epidemics in major metropolitan areas has always been a concern. In a vast and heterogeneous country, with regional disparities and climate diversity, several factors can modulate the dynamics of COVID-19. What should be the scenario for inner Brazil, and what can we do to control infection transmission in each of these locations? Here, a mathematical model is proposed to simulate disease transmission among individuals in several scenarios, differing by abiotic factors, social-economic factors, and effectiveness of mitigation strategies. The disease control relies on keeping all individuals’ social distancing and detecting, followed by isolating, infected ones. The model reinforces social distancing as the most efficient method to control disease transmission. Moreover, it also shows that improving the detection and isolation of infected individuals can loosen this mitigation strategy. Finally, the effectiveness of control may be different across the country, and understanding it can help set up public health strategies.
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spelling Addressing the COVID-19 transmission in inner Brazil by a mathematical modelIn 2020, the world experienced its very first pandemic of the globalized era. A novel coronavirus, SARS-CoV-2, is the causative agent of severe pneumonia and has rapidly spread through many nations, crashing health systems and leading a large number of people to death. In Brazil, the emergence of local epidemics in major metropolitan areas has always been a concern. In a vast and heterogeneous country, with regional disparities and climate diversity, several factors can modulate the dynamics of COVID-19. What should be the scenario for inner Brazil, and what can we do to control infection transmission in each of these locations? Here, a mathematical model is proposed to simulate disease transmission among individuals in several scenarios, differing by abiotic factors, social-economic factors, and effectiveness of mitigation strategies. The disease control relies on keeping all individuals’ social distancing and detecting, followed by isolating, infected ones. The model reinforces social distancing as the most efficient method to control disease transmission. Moreover, it also shows that improving the detection and isolation of infected individuals can loosen this mitigation strategy. Finally, the effectiveness of control may be different across the country, and understanding it can help set up public health strategies.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Medical School of Botucatu São Paulo State UniversityInstitute of Mathematics Statistics and Scientific Computing University of CampinasInstitute of Biosciences São Paulo State UniversityMedical School of Botucatu São Paulo State UniversityInstitute of Biosciences São Paulo State UniversityFAPESP: 18/24058-1FAPESP: 18/24811-1Universidade Estadual Paulista (UNESP)Universidade Estadual de Campinas (UNICAMP)Almeida, G. B. [UNESP]Vilches, T. N.Ferreira, C. P. [UNESP]Fortaleza, C. M.C.B. [UNESP]2022-04-28T19:40:17Z2022-04-28T19:40:17Z2021-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1038/s41598-021-90118-5Scientific Reports, v. 11, n. 1, 2021.2045-2322http://hdl.handle.net/11449/22175910.1038/s41598-021-90118-52-s2.0-85106608571Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengScientific Reportsinfo:eu-repo/semantics/openAccess2022-04-28T19:40:17Zoai:repositorio.unesp.br:11449/221759Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:10:28.902696Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Addressing the COVID-19 transmission in inner Brazil by a mathematical model
title Addressing the COVID-19 transmission in inner Brazil by a mathematical model
spellingShingle Addressing the COVID-19 transmission in inner Brazil by a mathematical model
Almeida, G. B. [UNESP]
title_short Addressing the COVID-19 transmission in inner Brazil by a mathematical model
title_full Addressing the COVID-19 transmission in inner Brazil by a mathematical model
title_fullStr Addressing the COVID-19 transmission in inner Brazil by a mathematical model
title_full_unstemmed Addressing the COVID-19 transmission in inner Brazil by a mathematical model
title_sort Addressing the COVID-19 transmission in inner Brazil by a mathematical model
author Almeida, G. B. [UNESP]
author_facet Almeida, G. B. [UNESP]
Vilches, T. N.
Ferreira, C. P. [UNESP]
Fortaleza, C. M.C.B. [UNESP]
author_role author
author2 Vilches, T. N.
Ferreira, C. P. [UNESP]
Fortaleza, C. M.C.B. [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidade Estadual de Campinas (UNICAMP)
dc.contributor.author.fl_str_mv Almeida, G. B. [UNESP]
Vilches, T. N.
Ferreira, C. P. [UNESP]
Fortaleza, C. M.C.B. [UNESP]
description In 2020, the world experienced its very first pandemic of the globalized era. A novel coronavirus, SARS-CoV-2, is the causative agent of severe pneumonia and has rapidly spread through many nations, crashing health systems and leading a large number of people to death. In Brazil, the emergence of local epidemics in major metropolitan areas has always been a concern. In a vast and heterogeneous country, with regional disparities and climate diversity, several factors can modulate the dynamics of COVID-19. What should be the scenario for inner Brazil, and what can we do to control infection transmission in each of these locations? Here, a mathematical model is proposed to simulate disease transmission among individuals in several scenarios, differing by abiotic factors, social-economic factors, and effectiveness of mitigation strategies. The disease control relies on keeping all individuals’ social distancing and detecting, followed by isolating, infected ones. The model reinforces social distancing as the most efficient method to control disease transmission. Moreover, it also shows that improving the detection and isolation of infected individuals can loosen this mitigation strategy. Finally, the effectiveness of control may be different across the country, and understanding it can help set up public health strategies.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-01
2022-04-28T19:40:17Z
2022-04-28T19:40:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1038/s41598-021-90118-5
Scientific Reports, v. 11, n. 1, 2021.
2045-2322
http://hdl.handle.net/11449/221759
10.1038/s41598-021-90118-5
2-s2.0-85106608571
url http://dx.doi.org/10.1038/s41598-021-90118-5
http://hdl.handle.net/11449/221759
identifier_str_mv Scientific Reports, v. 11, n. 1, 2021.
2045-2322
10.1038/s41598-021-90118-5
2-s2.0-85106608571
dc.language.iso.fl_str_mv eng
language eng
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instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
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