The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1678-7757-2020-0568 http://hdl.handle.net/11449/208285 |
Resumo: | Objective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants. |
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The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical studyBioactive glassBiomaterialsBone regenerationBone substitutesSinus floor augmentationTissue physiologyXenograftObjective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade do Grande Rio (UNIGRANRIO) Centro Universitário Serra dos Órgãos (UNIFESO)Centro Universitário Serra dos Órgãos (UNIFESO)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Universidade Estadual do Oeste do Paraná (UNIOESTE)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Centro Universitário Serra dos Órgãos (UNIFESO)Universidade Estadual Paulista (Unesp)Universidade Estadual do Oeste do Paraná (UNIOESTE)Pereira, Rodrigo dos SantosBonardi, João Paulo [UNESP]Ouverney, Felippe Ricardo FrossardCampos, Annelise BackerGriza, Geraldo LuizOkamoto, Roberta [UNESP]Hochuli-Vieira, Eduardo [UNESP]2021-06-25T11:09:39Z2021-06-25T11:09:39Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9application/pdfhttp://dx.doi.org/10.1590/1678-7757-2020-0568Journal of Applied Oral Science, v. 29, p. 1-9.1678-77651678-7757http://hdl.handle.net/11449/20828510.1590/1678-7757-2020-0568S1678-775720210001004022-s2.0-85098605973S1678-77572021000100402.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Scienceinfo:eu-repo/semantics/openAccess2024-09-19T14:02:54Zoai:repositorio.unesp.br:11449/208285Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T14:02:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
title |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
spellingShingle |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study Pereira, Rodrigo dos Santos Bioactive glass Biomaterials Bone regeneration Bone substitutes Sinus floor augmentation Tissue physiology Xenograft |
title_short |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
title_full |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
title_fullStr |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
title_full_unstemmed |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
title_sort |
The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study |
author |
Pereira, Rodrigo dos Santos |
author_facet |
Pereira, Rodrigo dos Santos Bonardi, João Paulo [UNESP] Ouverney, Felippe Ricardo Frossard Campos, Annelise Backer Griza, Geraldo Luiz Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
author_role |
author |
author2 |
Bonardi, João Paulo [UNESP] Ouverney, Felippe Ricardo Frossard Campos, Annelise Backer Griza, Geraldo Luiz Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Centro Universitário Serra dos Órgãos (UNIFESO) Universidade Estadual Paulista (Unesp) Universidade Estadual do Oeste do Paraná (UNIOESTE) |
dc.contributor.author.fl_str_mv |
Pereira, Rodrigo dos Santos Bonardi, João Paulo [UNESP] Ouverney, Felippe Ricardo Frossard Campos, Annelise Backer Griza, Geraldo Luiz Okamoto, Roberta [UNESP] Hochuli-Vieira, Eduardo [UNESP] |
dc.subject.por.fl_str_mv |
Bioactive glass Biomaterials Bone regeneration Bone substitutes Sinus floor augmentation Tissue physiology Xenograft |
topic |
Bioactive glass Biomaterials Bone regeneration Bone substitutes Sinus floor augmentation Tissue physiology Xenograft |
description |
Objective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T11:09:39Z 2021-06-25T11:09:39Z 2021-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-7757-2020-0568 Journal of Applied Oral Science, v. 29, p. 1-9. 1678-7765 1678-7757 http://hdl.handle.net/11449/208285 10.1590/1678-7757-2020-0568 S1678-77572021000100402 2-s2.0-85098605973 S1678-77572021000100402.pdf |
url |
http://dx.doi.org/10.1590/1678-7757-2020-0568 http://hdl.handle.net/11449/208285 |
identifier_str_mv |
Journal of Applied Oral Science, v. 29, p. 1-9. 1678-7765 1678-7757 10.1590/1678-7757-2020-0568 S1678-77572021000100402 2-s2.0-85098605973 S1678-77572021000100402.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-9 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1813546444759498752 |