The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study

Detalhes bibliográficos
Autor(a) principal: Pereira, Rodrigo dos Santos
Data de Publicação: 2021
Outros Autores: Bonardi, João Paulo [UNESP], Ouverney, Felippe Ricardo Frossard, Campos, Annelise Backer, Griza, Geraldo Luiz, Okamoto, Roberta [UNESP], Hochuli-Vieira, Eduardo [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-7757-2020-0568
http://hdl.handle.net/11449/208285
Resumo: Objective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.
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spelling The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical studyBioactive glassBiomaterialsBone regenerationBone substitutesSinus floor augmentationTissue physiologyXenograftObjective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade do Grande Rio (UNIGRANRIO) Centro Universitário Serra dos Órgãos (UNIFESO)Centro Universitário Serra dos Órgãos (UNIFESO)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Universidade Estadual do Oeste do Paraná (UNIOESTE)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Centro Universitário Serra dos Órgãos (UNIFESO)Universidade Estadual Paulista (Unesp)Universidade Estadual do Oeste do Paraná (UNIOESTE)Pereira, Rodrigo dos SantosBonardi, João Paulo [UNESP]Ouverney, Felippe Ricardo FrossardCampos, Annelise BackerGriza, Geraldo LuizOkamoto, Roberta [UNESP]Hochuli-Vieira, Eduardo [UNESP]2021-06-25T11:09:39Z2021-06-25T11:09:39Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9application/pdfhttp://dx.doi.org/10.1590/1678-7757-2020-0568Journal of Applied Oral Science, v. 29, p. 1-9.1678-77651678-7757http://hdl.handle.net/11449/20828510.1590/1678-7757-2020-0568S1678-775720210001004022-s2.0-85098605973S1678-77572021000100402.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Scienceinfo:eu-repo/semantics/openAccess2024-09-19T14:02:54Zoai:repositorio.unesp.br:11449/208285Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T14:02:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
title The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
spellingShingle The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
Pereira, Rodrigo dos Santos
Bioactive glass
Biomaterials
Bone regeneration
Bone substitutes
Sinus floor augmentation
Tissue physiology
Xenograft
title_short The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
title_full The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
title_fullStr The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
title_full_unstemmed The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
title_sort The new bone formation in human maxillary sinuses using two bone substitutes with different resorption types associated or not with autogenous bone graft: A comparative histomorphometric, immunohistochemical and randomized clinical study
author Pereira, Rodrigo dos Santos
author_facet Pereira, Rodrigo dos Santos
Bonardi, João Paulo [UNESP]
Ouverney, Felippe Ricardo Frossard
Campos, Annelise Backer
Griza, Geraldo Luiz
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
author_role author
author2 Bonardi, João Paulo [UNESP]
Ouverney, Felippe Ricardo Frossard
Campos, Annelise Backer
Griza, Geraldo Luiz
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro Universitário Serra dos Órgãos (UNIFESO)
Universidade Estadual Paulista (Unesp)
Universidade Estadual do Oeste do Paraná (UNIOESTE)
dc.contributor.author.fl_str_mv Pereira, Rodrigo dos Santos
Bonardi, João Paulo [UNESP]
Ouverney, Felippe Ricardo Frossard
Campos, Annelise Backer
Griza, Geraldo Luiz
Okamoto, Roberta [UNESP]
Hochuli-Vieira, Eduardo [UNESP]
dc.subject.por.fl_str_mv Bioactive glass
Biomaterials
Bone regeneration
Bone substitutes
Sinus floor augmentation
Tissue physiology
Xenograft
topic Bioactive glass
Biomaterials
Bone regeneration
Bone substitutes
Sinus floor augmentation
Tissue physiology
Xenograft
description Objective: The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology: 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results: In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion: This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T11:09:39Z
2021-06-25T11:09:39Z
2021-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-7757-2020-0568
Journal of Applied Oral Science, v. 29, p. 1-9.
1678-7765
1678-7757
http://hdl.handle.net/11449/208285
10.1590/1678-7757-2020-0568
S1678-77572021000100402
2-s2.0-85098605973
S1678-77572021000100402.pdf
url http://dx.doi.org/10.1590/1678-7757-2020-0568
http://hdl.handle.net/11449/208285
identifier_str_mv Journal of Applied Oral Science, v. 29, p. 1-9.
1678-7765
1678-7757
10.1590/1678-7757-2020-0568
S1678-77572021000100402
2-s2.0-85098605973
S1678-77572021000100402.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Applied Oral Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-9
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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