Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma

Detalhes bibliográficos
Autor(a) principal: Panis, C.
Data de Publicação: 2016
Outros Autores: Victorino, V. J. [UNESP], Herrera, A. C. S. A., Cecchini, A. L., Simao, A. N. C., Tomita, L. Y., Cecchini, R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1155/2016/6429812
http://hdl.handle.net/11449/158757
Resumo: In this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.
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spelling Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and PlasmaIn this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundacao AraucariaState Univ West Parana UNIOESTE, Lab Inflammatory Mediators, Campus Francisco Beltrao, BR-85605010 Francisco Beltrao, PR, BrazilState Univ Sao Paulo USP, Sch Med, BR-07112000 Sao Paulo, SP, BrazilPontificia Univ Catolica, Sch Med, Campus Londrina, BR-86051990 Londrina, PR, BrazilState Univ Londrina UEL, Dept Gen Pathol, Lab Physiopathol & Free Rad, BR-86051990 Londrina, PR, BrazilState Univ Londrina UEL, Dept Pharm, Univ Hosp, BR-86051990 Londrina, PR, BrazilFed Univ Sao Paulo UNIFESP, Dept Prevent Med, BR-07112000 Sao Paulo, BrazilState Univ Sao Paulo USP, Sch Med, BR-07112000 Sao Paulo, SP, BrazilHindawi LtdState Univ West Parana UNIOESTEUniversidade Estadual Paulista (Unesp)Pontificia Univ CatolicaUniversidade Estadual de Londrina (UEL)Universidade de São Paulo (USP)Panis, C.Victorino, V. J. [UNESP]Herrera, A. C. S. A.Cecchini, A. L.Simao, A. N. C.Tomita, L. Y.Cecchini, R.2018-11-26T15:28:54Z2018-11-26T15:28:54Z2016-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://dx.doi.org/10.1155/2016/6429812Oxidative Medicine And Cellular Longevity. London: Hindawi Ltd, 9 p., 2016.1942-0900http://hdl.handle.net/11449/15875710.1155/2016/6429812WOS:000372235600001WOS000372235600001.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengOxidative Medicine And Cellular Longevity1,558info:eu-repo/semantics/openAccess2024-01-01T06:19:12Zoai:repositorio.unesp.br:11449/158757Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:51:04.188044Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
title Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
spellingShingle Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
Panis, C.
title_short Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
title_full Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
title_fullStr Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
title_full_unstemmed Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
title_sort Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma
author Panis, C.
author_facet Panis, C.
Victorino, V. J. [UNESP]
Herrera, A. C. S. A.
Cecchini, A. L.
Simao, A. N. C.
Tomita, L. Y.
Cecchini, R.
author_role author
author2 Victorino, V. J. [UNESP]
Herrera, A. C. S. A.
Cecchini, A. L.
Simao, A. N. C.
Tomita, L. Y.
Cecchini, R.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv State Univ West Parana UNIOESTE
Universidade Estadual Paulista (Unesp)
Pontificia Univ Catolica
Universidade Estadual de Londrina (UEL)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Panis, C.
Victorino, V. J. [UNESP]
Herrera, A. C. S. A.
Cecchini, A. L.
Simao, A. N. C.
Tomita, L. Y.
Cecchini, R.
description In this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01
2018-11-26T15:28:54Z
2018-11-26T15:28:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1155/2016/6429812
Oxidative Medicine And Cellular Longevity. London: Hindawi Ltd, 9 p., 2016.
1942-0900
http://hdl.handle.net/11449/158757
10.1155/2016/6429812
WOS:000372235600001
WOS000372235600001.pdf
url http://dx.doi.org/10.1155/2016/6429812
http://hdl.handle.net/11449/158757
identifier_str_mv Oxidative Medicine And Cellular Longevity. London: Hindawi Ltd, 9 p., 2016.
1942-0900
10.1155/2016/6429812
WOS:000372235600001
WOS000372235600001.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Oxidative Medicine And Cellular Longevity
1,558
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.publisher.none.fl_str_mv Hindawi Ltd
publisher.none.fl_str_mv Hindawi Ltd
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129365970518016

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