Enxaguatório bucal livre de álcool contendo extrato da casca de romã, trimetafosfato de sódio e flúor: avaliação da quantidade de cálcio, fósforo e flúor em esmalte bovino após ciclagem de pH.

• Autor(a) principal: Costa, Thais Yuri Suzuki [UNESP]
• Data de Publicação: 2020
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/213868
• topic: Dental caries; Punicaceae; Polifosfatos; Fluoreto de sódio; Cárie dentária

The present study had as objective to analyse in vitro the effect of formulations for alcohol free mouthwashes containing pomegranate peel extract, sodium trimetaphosphate and sodium fluoride, under concentrations of calcium, phosphorus and flour in bovine enamel after pH cycling and treatment with these formulations. The pomegranate peel extract was obtained by alcoholic process through the process of maceration and filtration, it was standardized in % of solids and subjected to pharmacopoeial analyzes by Folin Denis colorimetry. Bovine enamel blocks (4 mm × 4 mm) selected by initial surface hardness (SHi) were randomly allocated according to groups of formulation treatments (n= 12/group): ETF1 (3.0% E + 0.2% TMP + 100 ppm F), TF1 (0.2% TMP + 100 ppm F), ETF2 (3.0% E + 0.3% TMP + 225 ppm F), TF2 (0.3% TMP + 225ppm F), F1 (100 ppm F), F2 (225 ppm F), and P (formulation without E/T/F - placebo). The blocks were treated 2x/day for 1 minute with each formulation and subjected to five pH cycles ( demineralizing/remineralizing solutions ) at 37° C. Next, the concentrations of fluoride (F), calcium (Ca) and phosphorus (P) in the bovine enamel were determined. Similar amounts of F were found in all formulations. The concentration of Ca, on the other hand, increased ± 30% in solution F2 in comparison with F1. Lastly, the concentration of phosphorus in the enamel was highest for formulation F2 when compared to formulation F1 = solution ETF1 = solution TF1 = solution ETF2 = solution TF2. It can be concluded that the addition of pomegranate ( Punica granatum ) peel extract at 3% in formulations for mouthwash containing TMP and F kept the concentrations of F, Ca and P in bovine enamel in in vitro trials of pH cycling, not harming the remineralizing activity. Thus, creating a promising prospect for the development of a commercial alcohol free dental product associating the already proven benefits of TMP and F with the millennial ones of Punica granatum .