Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus

Detalhes bibliográficos
Autor(a) principal: Rudge, Marilza V. C. [UNESP]
Data de Publicação: 2020
Outros Autores: Souza, Fátima P. [UNESP], Abbade, Joelcio F. [UNESP], Hallur, Raghavendra L. S. [UNESP], Marcondes, João Paulo C. [UNESP], Piculo, Fernanda [UNESP], Marini, Gabriela [UNESP], Vesentini, Giovana [UNESP], Thabane, Lehana, Witkin, Steven S., Calderon, Iracema M. P. [UNESP], Barbosa, Angélica M. P. [UNESP], Barbosa, A. M.P., Calderon, I. M.P., Souza, F. P., Abbade, J. F., Hallur, L. S.R., Piculo, F., Marini, G., Thabane, L., Palma, M. S., Graeff, C. F.O., Arni, R. K., Herculano, R. D., Salvadori, D. F., Mateus, S., Dal Pai Silva, M., Magalhães, C. G., Costa, R. A., Lima, S. A.M., Felisbino, S. L., Barbosa, W., Atallah, A., Girão, M. J.B., Di Bella, Z., Uchoa, S. M., Payão, S., Hijas, A., Berghman, B., De Bie, R., Sobrevia, L., Junginger, B., Alves, F. C.B., Rossignoli, P. S., Prudencio, C. B., Orlandi, M. I.G., Gonçalves, M. I., Nunes, S. K., Catinelli, B. B., Quiroz, S., Sarmento, B. V., Pinheiro, F. A., Sartorão, C. I., Lucas, R. R., Reyes, D. R.A., Quiroz, S. B.C.V., Enriquez, E. M.A., Oliveira, R. G., Floriano, J. F., Barneze, S., Dangió, T. D., Pascon, T., Rossignoli, P., Freitas, J. V., Takano, L., Reis, F., Caldeirão, T. D., Fernandes, J. N., Carr, A. M., Gaitero, M. V.C., Corrente, J. E., Nunes, H. R.C., Candido, A. F., Costa, S. M.B., Melo, J. V.F., Reis, F. V.D.S., Garcia, G. A., Rabadan, G. B., Bassin, H. C.M., Suyama, K. S., Damasceno, L. N., Takemoto, M. L.S., Menezes, M. D., Bussaneli, D. G., Nogueira, V. K.C., Lima, P. R., Lourenço, I. O., Marostica De Sá, J., Megid, R. A., Caruso, I. P., Rasmussen, L. T., Prata, G. M., Arantes, M. A., Ferraz, G. A.R., Camargo, L. P., Kron, M. R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/s12884-020-2749-x
http://hdl.handle.net/11449/200135
Resumo: Background: Pelvic floor muscles (PFM) and rectus abdominis muscles (RAM) of pregnant diabetic rats exhibit atrophy, co-localization of fast and slow fibers and an increased collagen type I/III ratio. However, the role of similar PFM or RAM hyperglycemic-related myopathy in women with gestational diabetes mellitus (GDM) remains poorly investigated. This study aims to assess the frequency of pelvic floor muscle disorders and pregnancy-specific urinary incontinence (PS-UI) 12 months after the Cesarean (C) section in women with GDM. Specifically, differences in PFM/RAM hyperglycemic myopathy will be evaluated. Methods: The Diamater is an ongoing cohort study of four groups of 59 pregnant women each from the Perinatal Diabetes Research Centre (PDRC), Botucatu Medical School (FMB)-UNESP (São Paulo State University), Brazil. Diagnosis of GDM and PS-UI will be made at 24-26 weeks, with a follow-up at 34-38 weeks of gestation. Inclusion in the study will occur at the time of C-section, and patients will be followed at 24-48 h, 6 weeks and 6 and 12 months postpartum. Study groups will be classified as (1) GDM plus PS-UI; (2) GDM without PS-UI; (3) Non-GDM plus PS-UI; and (4) Non-GDM without PS-UI. We will analyze relationships between GDM, PS-UI and hyperglycemic myopathy at 12 months after C-section. The mediator variables to be evaluated include digital palpation, vaginal squeeze pressure, 3D pelvic floor ultrasound, and 3D RAM ultrasound. RAM samples obtained during C-section will be analyzed for ex-vivo contractility, morphological, molecular and OMICS profiles to further characterize the hyperglycemic myopathy. Additional variables to be evaluated include maternal age, socioeconomic status, educational level, ethnicity, body mass index, weight gain during pregnancy, quality of glycemic control and insulin therapy. Discussion: To our knowledge, this will be the first study to provide data on the prevalence of PS-UI and RAM and PFM physical and biomolecular muscle profiles after C-section in mothers with GDM. The longitudinal design allows for the assessment of cause-effect relationships between GDM, PS-UI, and PFMs and RAMs myopathy. The findings may reveal previously undetermined consequences of GDM.
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spelling Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitusCollagenElectromyographyGestational diabetes mellitusHyperglycemic myopathyPelvic floor musclesProteomicsRectus abdominis musclesTransmission electron microscopyUrinary incontinenceBackground: Pelvic floor muscles (PFM) and rectus abdominis muscles (RAM) of pregnant diabetic rats exhibit atrophy, co-localization of fast and slow fibers and an increased collagen type I/III ratio. However, the role of similar PFM or RAM hyperglycemic-related myopathy in women with gestational diabetes mellitus (GDM) remains poorly investigated. This study aims to assess the frequency of pelvic floor muscle disorders and pregnancy-specific urinary incontinence (PS-UI) 12 months after the Cesarean (C) section in women with GDM. Specifically, differences in PFM/RAM hyperglycemic myopathy will be evaluated. Methods: The Diamater is an ongoing cohort study of four groups of 59 pregnant women each from the Perinatal Diabetes Research Centre (PDRC), Botucatu Medical School (FMB)-UNESP (São Paulo State University), Brazil. Diagnosis of GDM and PS-UI will be made at 24-26 weeks, with a follow-up at 34-38 weeks of gestation. Inclusion in the study will occur at the time of C-section, and patients will be followed at 24-48 h, 6 weeks and 6 and 12 months postpartum. Study groups will be classified as (1) GDM plus PS-UI; (2) GDM without PS-UI; (3) Non-GDM plus PS-UI; and (4) Non-GDM without PS-UI. We will analyze relationships between GDM, PS-UI and hyperglycemic myopathy at 12 months after C-section. The mediator variables to be evaluated include digital palpation, vaginal squeeze pressure, 3D pelvic floor ultrasound, and 3D RAM ultrasound. RAM samples obtained during C-section will be analyzed for ex-vivo contractility, morphological, molecular and OMICS profiles to further characterize the hyperglycemic myopathy. Additional variables to be evaluated include maternal age, socioeconomic status, educational level, ethnicity, body mass index, weight gain during pregnancy, quality of glycemic control and insulin therapy. Discussion: To our knowledge, this will be the first study to provide data on the prevalence of PS-UI and RAM and PFM physical and biomolecular muscle profiles after C-section in mothers with GDM. The longitudinal design allows for the assessment of cause-effect relationships between GDM, PS-UI, and PFMs and RAMs myopathy. The findings may reveal previously undetermined consequences of GDM.Department of Gynecology and Obstetrics Botucatu Medical School (FMB) São Paulo State University (UNESP)Physics Department Institute of Biosciences Letters and Exact Sciences Multiuser Center for Biomolecular Innovation UNESP-São Paulo State UniversityPhysiotherapy Department Faculdades Integradas de Bauru FIBUniversidade Do Sagrado Coração (USC), Jardim BrasilDepartment of Health Research Methods Evidence and Impact McMaster UniversityBiostatistics Unit Father Sean o'Sullivan Research Centre St Joseph's Healthcare-HamiltonDepartment of Obstetrics and Gynecology Weill Cornell MedicineInstitute of Tropical Medicine University of Sao Paulo Medical SchoolSchool of Philosophy and Sciences Department of Physiotherapy and Occupational Therapy UNESP-São Paulo State UniversityDepartment of Gynecology and Obstetrics Botucatu Medical School (FMB) São Paulo State University (UNESP)Physics Department Institute of Biosciences Letters and Exact Sciences Multiuser Center for Biomolecular Innovation UNESP-São Paulo State UniversitySchool of Philosophy and Sciences Department of Physiotherapy and Occupational Therapy UNESP-São Paulo State UniversityUniversidade Estadual Paulista (Unesp)FIBUniversidade Do Sagrado Coração (USC)McMaster UniversitySt Joseph's Healthcare-HamiltonWeill Cornell MedicineUniversidade de São Paulo (USP)Rudge, Marilza V. C. [UNESP]Souza, Fátima P. [UNESP]Abbade, Joelcio F. [UNESP]Hallur, Raghavendra L. S. [UNESP]Marcondes, João Paulo C. [UNESP]Piculo, Fernanda [UNESP]Marini, Gabriela [UNESP]Vesentini, Giovana [UNESP]Thabane, LehanaWitkin, Steven S.Calderon, Iracema M. P. [UNESP]Barbosa, Angélica M. P. [UNESP]Barbosa, A. M.P.Calderon, I. M.P.Souza, F. P.Abbade, J. F.Hallur, L. S.R.Piculo, F.Marini, G.Thabane, L.Palma, M. S.Graeff, C. F.O.Arni, R. K.Herculano, R. D.Salvadori, D. F.Mateus, S.Dal Pai Silva, M.Magalhães, C. G.Costa, R. A.Lima, S. A.M.Felisbino, S. L.Barbosa, W.Atallah, A.Girão, M. J.B.Di Bella, Z.Uchoa, S. M.Payão, S.Hijas, A.Berghman, B.De Bie, R.Sobrevia, L.Junginger, B.Alves, F. C.B.Rossignoli, P. S.Prudencio, C. B.Orlandi, M. I.G.Gonçalves, M. I.Nunes, S. K.Catinelli, B. B.Quiroz, S.Sarmento, B. V.Pinheiro, F. A.Sartorão, C. I.Lucas, R. R.Reyes, D. R.A.Quiroz, S. B.C.V.Enriquez, E. M.A.Oliveira, R. G.Floriano, J. F.Barneze, S.Dangió, T. D.Pascon, T.Rossignoli, P.Freitas, J. V.Takano, L.Reis, F.Caldeirão, T. D.Fernandes, J. N.Carr, A. M.Gaitero, M. V.C.Corrente, J. E.Nunes, H. R.C.Candido, A. F.Costa, S. M.B.Melo, J. V.F.Reis, F. V.D.S.Garcia, G. A.Rabadan, G. B.Bassin, H. C.M.Suyama, K. S.Damasceno, L. N.Takemoto, M. L.S.Menezes, M. D.Bussaneli, D. G.Nogueira, V. K.C.Lima, P. R.Lourenço, I. O.Marostica De Sá, J.Megid, R. A.Caruso, I. P.Rasmussen, L. T.Prata, G. M.Arantes, M. A.Ferraz, G. A.R.Camargo, L. P.Kron, M. R.2020-12-12T01:58:39Z2020-12-12T01:58:39Z2020-02-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1186/s12884-020-2749-xBMC Pregnancy and Childbirth, v. 20, n. 1, 2020.1471-2393http://hdl.handle.net/11449/20013510.1186/s12884-020-2749-x2-s2.0-8508114437491625089789458870000-0003-2460-1145Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBMC Pregnancy and Childbirthinfo:eu-repo/semantics/openAccess2024-08-16T14:06:43Zoai:repositorio.unesp.br:11449/200135Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T14:06:43Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
title Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
spellingShingle Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
Rudge, Marilza V. C. [UNESP]
Collagen
Electromyography
Gestational diabetes mellitus
Hyperglycemic myopathy
Pelvic floor muscles
Proteomics
Rectus abdominis muscles
Transmission electron microscopy
Urinary incontinence
title_short Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
title_full Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
title_fullStr Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
title_full_unstemmed Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
title_sort Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus
author Rudge, Marilza V. C. [UNESP]
author_facet Rudge, Marilza V. C. [UNESP]
Souza, Fátima P. [UNESP]
Abbade, Joelcio F. [UNESP]
Hallur, Raghavendra L. S. [UNESP]
Marcondes, João Paulo C. [UNESP]
Piculo, Fernanda [UNESP]
Marini, Gabriela [UNESP]
Vesentini, Giovana [UNESP]
Thabane, Lehana
Witkin, Steven S.
Calderon, Iracema M. P. [UNESP]
Barbosa, Angélica M. P. [UNESP]
Barbosa, A. M.P.
Calderon, I. M.P.
Souza, F. P.
Abbade, J. F.
Hallur, L. S.R.
Piculo, F.
Marini, G.
Thabane, L.
Palma, M. S.
Graeff, C. F.O.
Arni, R. K.
Herculano, R. D.
Salvadori, D. F.
Mateus, S.
Dal Pai Silva, M.
Magalhães, C. G.
Costa, R. A.
Lima, S. A.M.
Felisbino, S. L.
Barbosa, W.
Atallah, A.
Girão, M. J.B.
Di Bella, Z.
Uchoa, S. M.
Payão, S.
Hijas, A.
Berghman, B.
De Bie, R.
Sobrevia, L.
Junginger, B.
Alves, F. C.B.
Rossignoli, P. S.
Prudencio, C. B.
Orlandi, M. I.G.
Gonçalves, M. I.
Nunes, S. K.
Catinelli, B. B.
Quiroz, S.
Sarmento, B. V.
Pinheiro, F. A.
Sartorão, C. I.
Lucas, R. R.
Reyes, D. R.A.
Quiroz, S. B.C.V.
Enriquez, E. M.A.
Oliveira, R. G.
Floriano, J. F.
Barneze, S.
Dangió, T. D.
Pascon, T.
Rossignoli, P.
Freitas, J. V.
Takano, L.
Reis, F.
Caldeirão, T. D.
Fernandes, J. N.
Carr, A. M.
Gaitero, M. V.C.
Corrente, J. E.
Nunes, H. R.C.
Candido, A. F.
Costa, S. M.B.
Melo, J. V.F.
Reis, F. V.D.S.
Garcia, G. A.
Rabadan, G. B.
Bassin, H. C.M.
Suyama, K. S.
Damasceno, L. N.
Takemoto, M. L.S.
Menezes, M. D.
Bussaneli, D. G.
Nogueira, V. K.C.
Lima, P. R.
Lourenço, I. O.
Marostica De Sá, J.
Megid, R. A.
Caruso, I. P.
Rasmussen, L. T.
Prata, G. M.
Arantes, M. A.
Ferraz, G. A.R.
Camargo, L. P.
Kron, M. R.
author_role author
author2 Souza, Fátima P. [UNESP]
Abbade, Joelcio F. [UNESP]
Hallur, Raghavendra L. S. [UNESP]
Marcondes, João Paulo C. [UNESP]
Piculo, Fernanda [UNESP]
Marini, Gabriela [UNESP]
Vesentini, Giovana [UNESP]
Thabane, Lehana
Witkin, Steven S.
Calderon, Iracema M. P. [UNESP]
Barbosa, Angélica M. P. [UNESP]
Barbosa, A. M.P.
Calderon, I. M.P.
Souza, F. P.
Abbade, J. F.
Hallur, L. S.R.
Piculo, F.
Marini, G.
Thabane, L.
Palma, M. S.
Graeff, C. F.O.
Arni, R. K.
Herculano, R. D.
Salvadori, D. F.
Mateus, S.
Dal Pai Silva, M.
Magalhães, C. G.
Costa, R. A.
Lima, S. A.M.
Felisbino, S. L.
Barbosa, W.
Atallah, A.
Girão, M. J.B.
Di Bella, Z.
Uchoa, S. M.
Payão, S.
Hijas, A.
Berghman, B.
De Bie, R.
Sobrevia, L.
Junginger, B.
Alves, F. C.B.
Rossignoli, P. S.
Prudencio, C. B.
Orlandi, M. I.G.
Gonçalves, M. I.
Nunes, S. K.
Catinelli, B. B.
Quiroz, S.
Sarmento, B. V.
Pinheiro, F. A.
Sartorão, C. I.
Lucas, R. R.
Reyes, D. R.A.
Quiroz, S. B.C.V.
Enriquez, E. M.A.
Oliveira, R. G.
Floriano, J. F.
Barneze, S.
Dangió, T. D.
Pascon, T.
Rossignoli, P.
Freitas, J. V.
Takano, L.
Reis, F.
Caldeirão, T. D.
Fernandes, J. N.
Carr, A. M.
Gaitero, M. V.C.
Corrente, J. E.
Nunes, H. R.C.
Candido, A. F.
Costa, S. M.B.
Melo, J. V.F.
Reis, F. V.D.S.
Garcia, G. A.
Rabadan, G. B.
Bassin, H. C.M.
Suyama, K. S.
Damasceno, L. N.
Takemoto, M. L.S.
Menezes, M. D.
Bussaneli, D. G.
Nogueira, V. K.C.
Lima, P. R.
Lourenço, I. O.
Marostica De Sá, J.
Megid, R. A.
Caruso, I. P.
Rasmussen, L. T.
Prata, G. M.
Arantes, M. A.
Ferraz, G. A.R.
Camargo, L. P.
Kron, M. R.
author2_role author
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dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
FIB
Universidade Do Sagrado Coração (USC)
McMaster University
St Joseph's Healthcare-Hamilton
Weill Cornell Medicine
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Rudge, Marilza V. C. [UNESP]
Souza, Fátima P. [UNESP]
Abbade, Joelcio F. [UNESP]
Hallur, Raghavendra L. S. [UNESP]
Marcondes, João Paulo C. [UNESP]
Piculo, Fernanda [UNESP]
Marini, Gabriela [UNESP]
Vesentini, Giovana [UNESP]
Thabane, Lehana
Witkin, Steven S.
Calderon, Iracema M. P. [UNESP]
Barbosa, Angélica M. P. [UNESP]
Barbosa, A. M.P.
Calderon, I. M.P.
Souza, F. P.
Abbade, J. F.
Hallur, L. S.R.
Piculo, F.
Marini, G.
Thabane, L.
Palma, M. S.
Graeff, C. F.O.
Arni, R. K.
Herculano, R. D.
Salvadori, D. F.
Mateus, S.
Dal Pai Silva, M.
Magalhães, C. G.
Costa, R. A.
Lima, S. A.M.
Felisbino, S. L.
Barbosa, W.
Atallah, A.
Girão, M. J.B.
Di Bella, Z.
Uchoa, S. M.
Payão, S.
Hijas, A.
Berghman, B.
De Bie, R.
Sobrevia, L.
Junginger, B.
Alves, F. C.B.
Rossignoli, P. S.
Prudencio, C. B.
Orlandi, M. I.G.
Gonçalves, M. I.
Nunes, S. K.
Catinelli, B. B.
Quiroz, S.
Sarmento, B. V.
Pinheiro, F. A.
Sartorão, C. I.
Lucas, R. R.
Reyes, D. R.A.
Quiroz, S. B.C.V.
Enriquez, E. M.A.
Oliveira, R. G.
Floriano, J. F.
Barneze, S.
Dangió, T. D.
Pascon, T.
Rossignoli, P.
Freitas, J. V.
Takano, L.
Reis, F.
Caldeirão, T. D.
Fernandes, J. N.
Carr, A. M.
Gaitero, M. V.C.
Corrente, J. E.
Nunes, H. R.C.
Candido, A. F.
Costa, S. M.B.
Melo, J. V.F.
Reis, F. V.D.S.
Garcia, G. A.
Rabadan, G. B.
Bassin, H. C.M.
Suyama, K. S.
Damasceno, L. N.
Takemoto, M. L.S.
Menezes, M. D.
Bussaneli, D. G.
Nogueira, V. K.C.
Lima, P. R.
Lourenço, I. O.
Marostica De Sá, J.
Megid, R. A.
Caruso, I. P.
Rasmussen, L. T.
Prata, G. M.
Arantes, M. A.
Ferraz, G. A.R.
Camargo, L. P.
Kron, M. R.
dc.subject.por.fl_str_mv Collagen
Electromyography
Gestational diabetes mellitus
Hyperglycemic myopathy
Pelvic floor muscles
Proteomics
Rectus abdominis muscles
Transmission electron microscopy
Urinary incontinence
topic Collagen
Electromyography
Gestational diabetes mellitus
Hyperglycemic myopathy
Pelvic floor muscles
Proteomics
Rectus abdominis muscles
Transmission electron microscopy
Urinary incontinence
description Background: Pelvic floor muscles (PFM) and rectus abdominis muscles (RAM) of pregnant diabetic rats exhibit atrophy, co-localization of fast and slow fibers and an increased collagen type I/III ratio. However, the role of similar PFM or RAM hyperglycemic-related myopathy in women with gestational diabetes mellitus (GDM) remains poorly investigated. This study aims to assess the frequency of pelvic floor muscle disorders and pregnancy-specific urinary incontinence (PS-UI) 12 months after the Cesarean (C) section in women with GDM. Specifically, differences in PFM/RAM hyperglycemic myopathy will be evaluated. Methods: The Diamater is an ongoing cohort study of four groups of 59 pregnant women each from the Perinatal Diabetes Research Centre (PDRC), Botucatu Medical School (FMB)-UNESP (São Paulo State University), Brazil. Diagnosis of GDM and PS-UI will be made at 24-26 weeks, with a follow-up at 34-38 weeks of gestation. Inclusion in the study will occur at the time of C-section, and patients will be followed at 24-48 h, 6 weeks and 6 and 12 months postpartum. Study groups will be classified as (1) GDM plus PS-UI; (2) GDM without PS-UI; (3) Non-GDM plus PS-UI; and (4) Non-GDM without PS-UI. We will analyze relationships between GDM, PS-UI and hyperglycemic myopathy at 12 months after C-section. The mediator variables to be evaluated include digital palpation, vaginal squeeze pressure, 3D pelvic floor ultrasound, and 3D RAM ultrasound. RAM samples obtained during C-section will be analyzed for ex-vivo contractility, morphological, molecular and OMICS profiles to further characterize the hyperglycemic myopathy. Additional variables to be evaluated include maternal age, socioeconomic status, educational level, ethnicity, body mass index, weight gain during pregnancy, quality of glycemic control and insulin therapy. Discussion: To our knowledge, this will be the first study to provide data on the prevalence of PS-UI and RAM and PFM physical and biomolecular muscle profiles after C-section in mothers with GDM. The longitudinal design allows for the assessment of cause-effect relationships between GDM, PS-UI, and PFMs and RAMs myopathy. The findings may reveal previously undetermined consequences of GDM.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-12T01:58:39Z
2020-12-12T01:58:39Z
2020-02-19
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/s12884-020-2749-x
BMC Pregnancy and Childbirth, v. 20, n. 1, 2020.
1471-2393
http://hdl.handle.net/11449/200135
10.1186/s12884-020-2749-x
2-s2.0-85081144374
9162508978945887
0000-0003-2460-1145
url http://dx.doi.org/10.1186/s12884-020-2749-x
http://hdl.handle.net/11449/200135
identifier_str_mv BMC Pregnancy and Childbirth, v. 20, n. 1, 2020.
1471-2393
10.1186/s12884-020-2749-x
2-s2.0-85081144374
9162508978945887
0000-0003-2460-1145
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BMC Pregnancy and Childbirth
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reponame_str Repositório Institucional da UNESP
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repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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