Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/196106 |
Resumo: | Coagulase-negative staphylococci (CNS) are the microorganisms most frequently isolated from clinical materials and represent the leading cause of bacteremia in hospitals. The pathogenesis of infections caused by these bacteria can be aggravated due to antimicrobial resistance and virulence factors. Thus, the present study characterized the CNS species isolated from blood cultures from inpatients of the University Hospital of Botucatu School of Medicine for the detection of methicillin-resistant Staphylococcus (MRS) and staphylococcal enterotoxin genes. The gene mecA was detected in 83.7% CNS and the staphylococcal cassette chromosome mec was typed in MRS, indicating 45.8% type ILI, 25% type I, 11.1% type IV and 5.5% type II. The search for staphylococcal enterotoxin genes indicated that 77 samples were positive for at least one gene. The data obtained in this study highlight the importance of detecting and characterizing MRS and virulence factors to better understand the profile of the isolated CNS in order to appropriately treat infections caused by these microorganisms. |
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Repositório Institucional da UNESP |
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Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University HospitalCoagulase-negative staphylococcimecAenterotoxinsSCCmecPCRCoagulase-negative staphylococci (CNS) are the microorganisms most frequently isolated from clinical materials and represent the leading cause of bacteremia in hospitals. The pathogenesis of infections caused by these bacteria can be aggravated due to antimicrobial resistance and virulence factors. Thus, the present study characterized the CNS species isolated from blood cultures from inpatients of the University Hospital of Botucatu School of Medicine for the detection of methicillin-resistant Staphylococcus (MRS) and staphylococcal enterotoxin genes. The gene mecA was detected in 83.7% CNS and the staphylococcal cassette chromosome mec was typed in MRS, indicating 45.8% type ILI, 25% type I, 11.1% type IV and 5.5% type II. The search for staphylococcal enterotoxin genes indicated that 77 samples were positive for at least one gene. The data obtained in this study highlight the importance of detecting and characterizing MRS and virulence factors to better understand the profile of the isolated CNS in order to appropriately treat infections caused by these microorganisms.Univ Estadual Paulista, UNESP, Biosci Inst, Dept Microbiol & Immunol, Botucatu, SP, BrazilUniv Estadual Paulista, UNESP, Biosci Inst, Dept Microbiol & Immunol, Botucatu, SP, BrazilWorld Scientific Publ Co Pte LtdUniversidade Estadual Paulista (Unesp)Pereira, Valeria Cataneli [UNESP]Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP]MendezVilas, A.2020-12-10T19:33:37Z2020-12-10T19:33:37Z2011-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObject298-302Science And Technology Against Microbial Pathogens: Research, Development And Evaluation. Singapore: World Scientific Publ Co Pte Ltd, p. 298-302, 2011.http://hdl.handle.net/11449/196106WOS:000394471400058Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengScience And Technology Against Microbial Pathogens: Research, Development And Evaluationinfo:eu-repo/semantics/openAccess2021-10-23T03:21:55Zoai:repositorio.unesp.br:11449/196106Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:36:32.968470Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
title |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
spellingShingle |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital Pereira, Valeria Cataneli [UNESP] Coagulase-negative staphylococci mecA enterotoxins SCCmec PCR |
title_short |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
title_full |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
title_fullStr |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
title_full_unstemmed |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
title_sort |
Characterization of methicillin-resistant coagulase-negative Staphylococci Isolates from blood cultures in a Brazilian University Hospital |
author |
Pereira, Valeria Cataneli [UNESP] |
author_facet |
Pereira, Valeria Cataneli [UNESP] Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] MendezVilas, A. |
author_role |
author |
author2 |
Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] MendezVilas, A. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Pereira, Valeria Cataneli [UNESP] Ribeiro de Souza da Cunha, Maria de Lourdes [UNESP] MendezVilas, A. |
dc.subject.por.fl_str_mv |
Coagulase-negative staphylococci mecA enterotoxins SCCmec PCR |
topic |
Coagulase-negative staphylococci mecA enterotoxins SCCmec PCR |
description |
Coagulase-negative staphylococci (CNS) are the microorganisms most frequently isolated from clinical materials and represent the leading cause of bacteremia in hospitals. The pathogenesis of infections caused by these bacteria can be aggravated due to antimicrobial resistance and virulence factors. Thus, the present study characterized the CNS species isolated from blood cultures from inpatients of the University Hospital of Botucatu School of Medicine for the detection of methicillin-resistant Staphylococcus (MRS) and staphylococcal enterotoxin genes. The gene mecA was detected in 83.7% CNS and the staphylococcal cassette chromosome mec was typed in MRS, indicating 45.8% type ILI, 25% type I, 11.1% type IV and 5.5% type II. The search for staphylococcal enterotoxin genes indicated that 77 samples were positive for at least one gene. The data obtained in this study highlight the importance of detecting and characterizing MRS and virulence factors to better understand the profile of the isolated CNS in order to appropriately treat infections caused by these microorganisms. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 2020-12-10T19:33:37Z 2020-12-10T19:33:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Science And Technology Against Microbial Pathogens: Research, Development And Evaluation. Singapore: World Scientific Publ Co Pte Ltd, p. 298-302, 2011. http://hdl.handle.net/11449/196106 WOS:000394471400058 |
identifier_str_mv |
Science And Technology Against Microbial Pathogens: Research, Development And Evaluation. Singapore: World Scientific Publ Co Pte Ltd, p. 298-302, 2011. WOS:000394471400058 |
url |
http://hdl.handle.net/11449/196106 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Science And Technology Against Microbial Pathogens: Research, Development And Evaluation |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
298-302 |
dc.publisher.none.fl_str_mv |
World Scientific Publ Co Pte Ltd |
publisher.none.fl_str_mv |
World Scientific Publ Co Pte Ltd |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129095332003840 |