Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications

Detalhes bibliográficos
Autor(a) principal: Pereira Rodrigues, Isabella Caroline
Data de Publicação: 2020
Outros Autores: Tamborlin, Leticia [UNESP], Rodrigues, Ana Amelia, Jardini, Andre Luiz, Luchessi, Augusto Ducati [UNESP], Maciel Filho, Rubens, Najar Lopes, Eder Socrates, Gabriel, Lais Pellizzer
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1002/app.48455
http://hdl.handle.net/11449/195268
Resumo: Polymeric membranes have gained popularity as fibrous structures for tissue regeneration. This research focuses on the rotary jet spinning (RJS) process combined with a polymer as a strategy for designing membranes. To this end, RJS-polyurethane (RJS-PU) membranes with different microstructures were produced. Considering the effects of solution properties on fiber production, the viscosity of PU solutions was evaluated. Membrane morphology was studied based on scanning electron microscopy and 2D fast Fourier transform analysis. The chemical and thermal properties were characterized by Fourier-transform infrared spectroscopy and thermogravimetric analysis, respectively. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and Live/Dead cell assays were performed to determine the material cytotoxicity by assessment of the profile of proliferation and cell viability. The results indicated that the combination of PU and RJS was an effective one for the production of fibrous structures for tissue engineering applications, demonstrating good compatibility with the cultured osteoblastic cell line. (c) 2019 Wiley Periodicals, Inc.
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spelling Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applicationsbiomaterialsfibersmanufacturingpolyurethanescaffoldsPolymeric membranes have gained popularity as fibrous structures for tissue regeneration. This research focuses on the rotary jet spinning (RJS) process combined with a polymer as a strategy for designing membranes. To this end, RJS-polyurethane (RJS-PU) membranes with different microstructures were produced. Considering the effects of solution properties on fiber production, the viscosity of PU solutions was evaluated. Membrane morphology was studied based on scanning electron microscopy and 2D fast Fourier transform analysis. The chemical and thermal properties were characterized by Fourier-transform infrared spectroscopy and thermogravimetric analysis, respectively. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and Live/Dead cell assays were performed to determine the material cytotoxicity by assessment of the profile of proliferation and cell viability. The results indicated that the combination of PU and RJS was an effective one for the production of fibrous structures for tissue engineering applications, demonstrating good compatibility with the cultured osteoblastic cell line. (c) 2019 Wiley Periodicals, Inc.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Estadual Campinas, Sch Appl Sci, Limeira, SP, BrazilSao Paulo State Univ, Inst Biosci, Rio Claro, SP, BrazilUniv Estadual Campinas, Sch Med Sci, Campinas, SP, BrazilNatl Inst Biofabricat, Campinas, SP, BrazilUniv Estadual Campinas, Sch Chem Engn, Campinas, SP, BrazilUniv Estadual Campinas, Sch Mech Engn, Campinas, SP, BrazilSao Paulo State Univ, Inst Biosci, Rio Claro, SP, BrazilFAPESP: 2017/13273-6FAPESP: 2008/57860-3Wiley-BlackwellUniversidade Estadual de Campinas (UNICAMP)Universidade Estadual Paulista (Unesp)Natl Inst BiofabricatPereira Rodrigues, Isabella CarolineTamborlin, Leticia [UNESP]Rodrigues, Ana AmeliaJardini, Andre LuizLuchessi, Augusto Ducati [UNESP]Maciel Filho, RubensNajar Lopes, Eder SocratesGabriel, Lais Pellizzer2020-12-10T17:28:59Z2020-12-10T17:28:59Z2020-03-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10http://dx.doi.org/10.1002/app.48455Journal Of Applied Polymer Science. Hoboken: Wiley, v. 137, n. 11, 10 p., 2020.0021-8995http://hdl.handle.net/11449/19526810.1002/app.48455WOS:000521655000002Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of Applied Polymer Scienceinfo:eu-repo/semantics/openAccess2021-10-23T07:14:20Zoai:repositorio.unesp.br:11449/195268Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:08:53.893920Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
title Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
spellingShingle Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
Pereira Rodrigues, Isabella Caroline
biomaterials
fibers
manufacturing
polyurethane
scaffolds
title_short Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
title_full Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
title_fullStr Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
title_full_unstemmed Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
title_sort Polyurethane fibrous membranes tailored by rotary jet spinning for tissue engineering applications
author Pereira Rodrigues, Isabella Caroline
author_facet Pereira Rodrigues, Isabella Caroline
Tamborlin, Leticia [UNESP]
Rodrigues, Ana Amelia
Jardini, Andre Luiz
Luchessi, Augusto Ducati [UNESP]
Maciel Filho, Rubens
Najar Lopes, Eder Socrates
Gabriel, Lais Pellizzer
author_role author
author2 Tamborlin, Leticia [UNESP]
Rodrigues, Ana Amelia
Jardini, Andre Luiz
Luchessi, Augusto Ducati [UNESP]
Maciel Filho, Rubens
Najar Lopes, Eder Socrates
Gabriel, Lais Pellizzer
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual Paulista (Unesp)
Natl Inst Biofabricat
dc.contributor.author.fl_str_mv Pereira Rodrigues, Isabella Caroline
Tamborlin, Leticia [UNESP]
Rodrigues, Ana Amelia
Jardini, Andre Luiz
Luchessi, Augusto Ducati [UNESP]
Maciel Filho, Rubens
Najar Lopes, Eder Socrates
Gabriel, Lais Pellizzer
dc.subject.por.fl_str_mv biomaterials
fibers
manufacturing
polyurethane
scaffolds
topic biomaterials
fibers
manufacturing
polyurethane
scaffolds
description Polymeric membranes have gained popularity as fibrous structures for tissue regeneration. This research focuses on the rotary jet spinning (RJS) process combined with a polymer as a strategy for designing membranes. To this end, RJS-polyurethane (RJS-PU) membranes with different microstructures were produced. Considering the effects of solution properties on fiber production, the viscosity of PU solutions was evaluated. Membrane morphology was studied based on scanning electron microscopy and 2D fast Fourier transform analysis. The chemical and thermal properties were characterized by Fourier-transform infrared spectroscopy and thermogravimetric analysis, respectively. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and Live/Dead cell assays were performed to determine the material cytotoxicity by assessment of the profile of proliferation and cell viability. The results indicated that the combination of PU and RJS was an effective one for the production of fibrous structures for tissue engineering applications, demonstrating good compatibility with the cultured osteoblastic cell line. (c) 2019 Wiley Periodicals, Inc.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-10T17:28:59Z
2020-12-10T17:28:59Z
2020-03-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1002/app.48455
Journal Of Applied Polymer Science. Hoboken: Wiley, v. 137, n. 11, 10 p., 2020.
0021-8995
http://hdl.handle.net/11449/195268
10.1002/app.48455
WOS:000521655000002
url http://dx.doi.org/10.1002/app.48455
http://hdl.handle.net/11449/195268
identifier_str_mv Journal Of Applied Polymer Science. Hoboken: Wiley, v. 137, n. 11, 10 p., 2020.
0021-8995
10.1002/app.48455
WOS:000521655000002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal Of Applied Polymer Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10
dc.publisher.none.fl_str_mv Wiley-Blackwell
publisher.none.fl_str_mv Wiley-Blackwell
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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