Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis

Detalhes bibliográficos
Autor(a) principal: Ângelo Tavares Schwarzmeier, Lígia [UNESP]
Data de Publicação: 2019
Outros Autores: Kitakawa, Dárcio, Eduardo Blumer Rosa, Luiz [UNESP], Antonio Guimarães Cabral, Luiz [UNESP], Dias Almeida, Janete [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.14295/bds.2019.v22i4.1714
http://hdl.handle.net/11449/199719
Resumo: A nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity.
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spelling Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritisMetotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenileArthritisGranulomaJuvenileLipMethotrexatePyogenicA nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity.Paulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and DiagnosisPaulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and DiagnosisUniversidade Estadual Paulista (Unesp)Ângelo Tavares Schwarzmeier, Lígia [UNESP]Kitakawa, DárcioEduardo Blumer Rosa, Luiz [UNESP]Antonio Guimarães Cabral, Luiz [UNESP]Dias Almeida, Janete [UNESP]2020-12-12T01:47:29Z2020-12-12T01:47:29Z2019-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article569-572http://dx.doi.org/10.14295/bds.2019.v22i4.1714Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019.2178-6011http://hdl.handle.net/11449/19971910.14295/bds.2019.v22i4.17142-s2.0-85075611330Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Dental Scienceinfo:eu-repo/semantics/openAccess2021-10-23T09:13:42Zoai:repositorio.unesp.br:11449/199719Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T09:13:42Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
Metotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenile
title Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
spellingShingle Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
Ângelo Tavares Schwarzmeier, Lígia [UNESP]
Arthritis
Granuloma
Juvenile
Lip
Methotrexate
Pyogenic
title_short Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
title_full Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
title_fullStr Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
title_full_unstemmed Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
title_sort Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
author Ângelo Tavares Schwarzmeier, Lígia [UNESP]
author_facet Ângelo Tavares Schwarzmeier, Lígia [UNESP]
Kitakawa, Dárcio
Eduardo Blumer Rosa, Luiz [UNESP]
Antonio Guimarães Cabral, Luiz [UNESP]
Dias Almeida, Janete [UNESP]
author_role author
author2 Kitakawa, Dárcio
Eduardo Blumer Rosa, Luiz [UNESP]
Antonio Guimarães Cabral, Luiz [UNESP]
Dias Almeida, Janete [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Ângelo Tavares Schwarzmeier, Lígia [UNESP]
Kitakawa, Dárcio
Eduardo Blumer Rosa, Luiz [UNESP]
Antonio Guimarães Cabral, Luiz [UNESP]
Dias Almeida, Janete [UNESP]
dc.subject.por.fl_str_mv Arthritis
Granuloma
Juvenile
Lip
Methotrexate
Pyogenic
topic Arthritis
Granuloma
Juvenile
Lip
Methotrexate
Pyogenic
description A nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-01
2020-12-12T01:47:29Z
2020-12-12T01:47:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.14295/bds.2019.v22i4.1714
Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019.
2178-6011
http://hdl.handle.net/11449/199719
10.14295/bds.2019.v22i4.1714
2-s2.0-85075611330
url http://dx.doi.org/10.14295/bds.2019.v22i4.1714
http://hdl.handle.net/11449/199719
identifier_str_mv Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019.
2178-6011
10.14295/bds.2019.v22i4.1714
2-s2.0-85075611330
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Dental Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 569-572
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964544858062848

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