Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.14295/bds.2019.v22i4.1714 http://hdl.handle.net/11449/199719 |
Resumo: | A nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity. |
id |
UNSP_bb163a48cb7c6699400b72fd51fc9c4e |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/199719 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritisMetotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenileArthritisGranulomaJuvenileLipMethotrexatePyogenicA nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity.Paulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and DiagnosisPaulo State University (Unesp) - Institute of Science and Technology São José dos Campos Department of Biosciences and DiagnosisUniversidade Estadual Paulista (Unesp)Ângelo Tavares Schwarzmeier, Lígia [UNESP]Kitakawa, DárcioEduardo Blumer Rosa, Luiz [UNESP]Antonio Guimarães Cabral, Luiz [UNESP]Dias Almeida, Janete [UNESP]2020-12-12T01:47:29Z2020-12-12T01:47:29Z2019-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article569-572http://dx.doi.org/10.14295/bds.2019.v22i4.1714Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019.2178-6011http://hdl.handle.net/11449/19971910.14295/bds.2019.v22i4.17142-s2.0-85075611330Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Dental Scienceinfo:eu-repo/semantics/openAccess2021-10-23T09:13:42Zoai:repositorio.unesp.br:11449/199719Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:47:01.724899Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis Metotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenile |
title |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
spellingShingle |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis Ângelo Tavares Schwarzmeier, Lígia [UNESP] Arthritis Granuloma Juvenile Lip Methotrexate Pyogenic |
title_short |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
title_full |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
title_fullStr |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
title_full_unstemmed |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
title_sort |
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritis |
author |
Ângelo Tavares Schwarzmeier, Lígia [UNESP] |
author_facet |
Ângelo Tavares Schwarzmeier, Lígia [UNESP] Kitakawa, Dárcio Eduardo Blumer Rosa, Luiz [UNESP] Antonio Guimarães Cabral, Luiz [UNESP] Dias Almeida, Janete [UNESP] |
author_role |
author |
author2 |
Kitakawa, Dárcio Eduardo Blumer Rosa, Luiz [UNESP] Antonio Guimarães Cabral, Luiz [UNESP] Dias Almeida, Janete [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Ângelo Tavares Schwarzmeier, Lígia [UNESP] Kitakawa, Dárcio Eduardo Blumer Rosa, Luiz [UNESP] Antonio Guimarães Cabral, Luiz [UNESP] Dias Almeida, Janete [UNESP] |
dc.subject.por.fl_str_mv |
Arthritis Granuloma Juvenile Lip Methotrexate Pyogenic |
topic |
Arthritis Granuloma Juvenile Lip Methotrexate Pyogenic |
description |
A nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by histopathological analysis. After the 7th and 15th days, the lip where biopsy had been done exhibited a deficient healing. The case was discussed with the physician for temporary suspension of methotrexate. Complete wound healing of the biopsied site occurred after temporary interruption of the medication. Wound healing after methotrexate temporary suspension allowed concluding that the drug delayed surgical wound healing was a consequence of drug cytotoxicity. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-01 2020-12-12T01:47:29Z 2020-12-12T01:47:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.14295/bds.2019.v22i4.1714 Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019. 2178-6011 http://hdl.handle.net/11449/199719 10.14295/bds.2019.v22i4.1714 2-s2.0-85075611330 |
url |
http://dx.doi.org/10.14295/bds.2019.v22i4.1714 http://hdl.handle.net/11449/199719 |
identifier_str_mv |
Brazilian Dental Science, v. 22, n. 4, p. 569-572, 2019. 2178-6011 10.14295/bds.2019.v22i4.1714 2-s2.0-85075611330 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Dental Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
569-572 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128416778551296 |