Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1155/2022/4439681 http://hdl.handle.net/11449/230429 |
Resumo: | Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. As a result of the rapid progression and severity of the disease, people with ALS experience loss of functionality and independence. Furthermore, it has already been described presence of autonomic dysfunction. Despite the increasing use of virtual reality (VR) in the treatment of different diseases, the use of virtual reality environment as an intervention program for ALS patients is innovative. The benefits and limitations have not yet been proven. Our objective was to evaluate the autonomic function of individuals with amyotrophic lateral sclerosis throughout the virtual reality task. The analysis of autonomic function was completed before, during, and after the virtual reality task using the upper limbs; also, all steps lasted ten minutes in a sitting position. Heart rate variability (HRV) was taken via the Polar® RS800CX cardiofrequencymeter. The following questionnaire was enforced: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS) and Fatigue Severity Scale (FSS). Different types of HRV were revealed for the groups, indicating that the ALS group has reduced HRV, with most of the representative indices of the sympathetic nervous system. Besides, the physiological process of reducing parasympathetic activity from rest to VR activity (vagal withdrawal), with reduction in HF (ms2) and an increase in HR from rest to activity, and a further increase throughout recovery, with withdrawal of sympathetic nervous system, occurs just for the control group (CG), with no alterations between rest, activity, and recovery in individuals with ALS. We could conclude that patients with ALS have the reduction of HRV with the sympathetic predominance when equated to the healthy CG. Besides that, the ALS individuals have no capability to adapt the autonomic nervous system when likened to the CG during therapy based on VR and their recovery. |
id |
UNSP_bbc5ee5a922b3809e5797a9b61e3d16e |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/230429 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control TrialAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. As a result of the rapid progression and severity of the disease, people with ALS experience loss of functionality and independence. Furthermore, it has already been described presence of autonomic dysfunction. Despite the increasing use of virtual reality (VR) in the treatment of different diseases, the use of virtual reality environment as an intervention program for ALS patients is innovative. The benefits and limitations have not yet been proven. Our objective was to evaluate the autonomic function of individuals with amyotrophic lateral sclerosis throughout the virtual reality task. The analysis of autonomic function was completed before, during, and after the virtual reality task using the upper limbs; also, all steps lasted ten minutes in a sitting position. Heart rate variability (HRV) was taken via the Polar® RS800CX cardiofrequencymeter. The following questionnaire was enforced: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS) and Fatigue Severity Scale (FSS). Different types of HRV were revealed for the groups, indicating that the ALS group has reduced HRV, with most of the representative indices of the sympathetic nervous system. Besides, the physiological process of reducing parasympathetic activity from rest to VR activity (vagal withdrawal), with reduction in HF (ms2) and an increase in HR from rest to activity, and a further increase throughout recovery, with withdrawal of sympathetic nervous system, occurs just for the control group (CG), with no alterations between rest, activity, and recovery in individuals with ALS. We could conclude that patients with ALS have the reduction of HRV with the sympathetic predominance when equated to the healthy CG. Besides that, the ALS individuals have no capability to adapt the autonomic nervous system when likened to the CG during therapy based on VR and their recovery.Postgraduate Program in Physical Activity Sciences School of Arts Science and Humanities of University of São Paulo (EACH-USP), SPPostgraduate Program in Rehabilitation Sciences Faculty of Medicine University of São Paulo (FMUSP), SPDepartment of Neurology and Neurosurgery at Paulista School of Medicine Federal University of São Paulo (EPM/UNIFESP), SPDepartment of Physiotherapy Mackenzie Presbyterian University, SPCardiorespiratory Research Group Department of Biological and Medical Sciences Faculty of Health and Life Sciences Oxford Brookes University Headington Campus, Gipsy LanePostgraduate Program in Information Systems School of Arts Science and Humanities of University of São Paulo (EACH-USP), SPDepartment of Physiotherapy Paulista State University (UNESP) Presidente Prudente, SPPostgraduate Program in Medicine (Cardiology) Escola Paulista de Medicina Federal University of São Paulo (EPM/UNIFESP), SPFaculty of Medicine City of São Paulo University (UNICID), SPDepartment of Physiotherapy Paulista State University (UNESP) Presidente Prudente, SPUniversidade de São Paulo (USP)Mackenzie Presbyterian UniversityHeadington CampusUniversidade Estadual Paulista (UNESP)Silveira, Ana C.Moraes, Íbis A. P.Vidigal, Giovanna P.Simcsik, Amanda O.Rosa, Renata M.Favero, Francis M.Fernandes, Susi M. S.Garner, David M.Araújo, Luciano V.Massa, MarceloVanderlei, Luiz C. M. [UNESP]Silva, Talita D.Monteiro, Carlos B. M.2022-04-29T08:39:54Z2022-04-29T08:39:54Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1155/2022/4439681BioMed Research International, v. 2022.2314-61412314-6133http://hdl.handle.net/11449/23042910.1155/2022/44396812-s2.0-85125003110Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBioMed Research Internationalinfo:eu-repo/semantics/openAccess2024-06-18T18:44:15Zoai:repositorio.unesp.br:11449/230429Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:13:35.226449Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
title |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
spellingShingle |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial Silveira, Ana C. |
title_short |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
title_full |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
title_fullStr |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
title_full_unstemmed |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
title_sort |
Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial |
author |
Silveira, Ana C. |
author_facet |
Silveira, Ana C. Moraes, Íbis A. P. Vidigal, Giovanna P. Simcsik, Amanda O. Rosa, Renata M. Favero, Francis M. Fernandes, Susi M. S. Garner, David M. Araújo, Luciano V. Massa, Marcelo Vanderlei, Luiz C. M. [UNESP] Silva, Talita D. Monteiro, Carlos B. M. |
author_role |
author |
author2 |
Moraes, Íbis A. P. Vidigal, Giovanna P. Simcsik, Amanda O. Rosa, Renata M. Favero, Francis M. Fernandes, Susi M. S. Garner, David M. Araújo, Luciano V. Massa, Marcelo Vanderlei, Luiz C. M. [UNESP] Silva, Talita D. Monteiro, Carlos B. M. |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Mackenzie Presbyterian University Headington Campus Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Silveira, Ana C. Moraes, Íbis A. P. Vidigal, Giovanna P. Simcsik, Amanda O. Rosa, Renata M. Favero, Francis M. Fernandes, Susi M. S. Garner, David M. Araújo, Luciano V. Massa, Marcelo Vanderlei, Luiz C. M. [UNESP] Silva, Talita D. Monteiro, Carlos B. M. |
description |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. As a result of the rapid progression and severity of the disease, people with ALS experience loss of functionality and independence. Furthermore, it has already been described presence of autonomic dysfunction. Despite the increasing use of virtual reality (VR) in the treatment of different diseases, the use of virtual reality environment as an intervention program for ALS patients is innovative. The benefits and limitations have not yet been proven. Our objective was to evaluate the autonomic function of individuals with amyotrophic lateral sclerosis throughout the virtual reality task. The analysis of autonomic function was completed before, during, and after the virtual reality task using the upper limbs; also, all steps lasted ten minutes in a sitting position. Heart rate variability (HRV) was taken via the Polar® RS800CX cardiofrequencymeter. The following questionnaire was enforced: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS) and Fatigue Severity Scale (FSS). Different types of HRV were revealed for the groups, indicating that the ALS group has reduced HRV, with most of the representative indices of the sympathetic nervous system. Besides, the physiological process of reducing parasympathetic activity from rest to VR activity (vagal withdrawal), with reduction in HF (ms2) and an increase in HR from rest to activity, and a further increase throughout recovery, with withdrawal of sympathetic nervous system, occurs just for the control group (CG), with no alterations between rest, activity, and recovery in individuals with ALS. We could conclude that patients with ALS have the reduction of HRV with the sympathetic predominance when equated to the healthy CG. Besides that, the ALS individuals have no capability to adapt the autonomic nervous system when likened to the CG during therapy based on VR and their recovery. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-29T08:39:54Z 2022-04-29T08:39:54Z 2022-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2022/4439681 BioMed Research International, v. 2022. 2314-6141 2314-6133 http://hdl.handle.net/11449/230429 10.1155/2022/4439681 2-s2.0-85125003110 |
url |
http://dx.doi.org/10.1155/2022/4439681 http://hdl.handle.net/11449/230429 |
identifier_str_mv |
BioMed Research International, v. 2022. 2314-6141 2314-6133 10.1155/2022/4439681 2-s2.0-85125003110 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BioMed Research International |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129175184211968 |