Variação da distribuição do diâmetro eritrocitário e do volume corpuscular médio em cães anêmicos

• Autor(a) principal: Gonçalves, Daniele Silvano [UNESP]
• Data de Publicação: 2014
• Outros Autores: Almeida, Breno F. M. [UNESP], Bomfim, Suley Regina Mogami [UNESP], Ciarlini, Paulo César [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.15361/2175-0106.2014v30n2p115-119; http://hdl.handle.net/11449/133075
• topic: Anemia; MCV; RDW; Reticulocite; Anemia; RDW; Reticulócitos; VCM

The anisocytosis is a hematologic finding that is routinely evaluated from the mean corpuscular volume (MCV) and erythrocyte morphology in assessment of blood smears. The present study tested the hypothesis that the coefficient of variation of the red cell distribution width (RDW-CV - Red Cell Distribution Width) is a more sensitive parameter in the evaluation of hematologic anisocytosis, considering different levels of anemia in dogs and reticulocytosis. Blood counts of 102 anemic dogs and 353 control dogs made by automated hematology counter. The anemic animals were grouped according to the degree of anemia (mild, moderate and severe) and also as medullary response by manual reticulocyte count (none, weak, moderate and strong). The RDW-CV was different to the animal groups with moderate and severe anemia, which were higher, compared to the control group and mild anemia. The highest average value of RDW-CV (14.45%) occurred in patients with severe anemia. In the control group had higher MCV value that anemic animals , this may be due to a mixed population of erythrocytes in that group of animals. However, there wasn’t difference in MCV between different degrees of anemia and reticulocytosis. Therefore, the RDW is a more sensitive indicator anisocytosis than VCM and its value is directly proportional to the degree of anemia and reticulocytosis; when combined, the sensitivity for detection of anisocytosis in anemic dogs is greater. The use of reference values established by the clinical laboratory itself is mighty important.