Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study

Detalhes bibliográficos
Autor(a) principal: Rego, Rebeca Mayara Padilha [UNESP]
Data de Publicação: 2019
Outros Autores: Machado, Nilton Carlos [UNESP], Carvalho, Mary de Assis [UNESP], Graffunder, Johann Souza [UNESP], Ortolan, Erika Veruska Paiva [UNESP], Lourenção, Pedro Luiz Toledo de Arruda [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1097/MD.0000000000017755
http://hdl.handle.net/11449/199629
Resumo: INTRODUCTION: A vast majority of children with functional constipation respond to the standard medical treatment. However, a subset of patients may present with an unsatisfactory response and only minor improvement of symptoms. Transcutaneous posterior tibial nerve stimulation (PTNS) involves electrical stimulation of the posterior tibial nerve at the level of the ankle, transcutaneously through electrodes fixated on the overlying skin. Stimulation of the tibial nerve can modulate urinary and defecatory function through the stimulation of sacral nerves. Thus, transcutaneous PTNS can be considered a very promising, noninvasive, and safe method to be used in the pediatric age group. However, there is still no published study that has investigated its use in children for the treatment of intestinal constipation. This is a single-center, prospective, longitudinal, and interventional study designed to assess the applicability and clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation. Children will be submitted to daily sessions of transcutaneous PTNS for a period of 4 weeks. All children will also be invited to participate in semistructured interviews, 1 in each of the 3 assessments: 1 week before the start of the intervention; immediately after the 4 weeks of intervention; and 4 weeks after the end of the intervention period. In these interviews, the aspects related to bowel habits and quality of life will be assessed. This project aims to evaluate the clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation and the applicability of this kind of treatment. CONCLUSIONS: This protocol intended to demonstrate the efficacy of this promising method to increase the number of bowel movements and the stool consistency, to reduce the number of episodes of retentive fecal incontinence, and to indirectly improve the overall quality of life.
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spelling Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional studyINTRODUCTION: A vast majority of children with functional constipation respond to the standard medical treatment. However, a subset of patients may present with an unsatisfactory response and only minor improvement of symptoms. Transcutaneous posterior tibial nerve stimulation (PTNS) involves electrical stimulation of the posterior tibial nerve at the level of the ankle, transcutaneously through electrodes fixated on the overlying skin. Stimulation of the tibial nerve can modulate urinary and defecatory function through the stimulation of sacral nerves. Thus, transcutaneous PTNS can be considered a very promising, noninvasive, and safe method to be used in the pediatric age group. However, there is still no published study that has investigated its use in children for the treatment of intestinal constipation. This is a single-center, prospective, longitudinal, and interventional study designed to assess the applicability and clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation. Children will be submitted to daily sessions of transcutaneous PTNS for a period of 4 weeks. All children will also be invited to participate in semistructured interviews, 1 in each of the 3 assessments: 1 week before the start of the intervention; immediately after the 4 weeks of intervention; and 4 weeks after the end of the intervention period. In these interviews, the aspects related to bowel habits and quality of life will be assessed. This project aims to evaluate the clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation and the applicability of this kind of treatment. CONCLUSIONS: This protocol intended to demonstrate the efficacy of this promising method to increase the number of bowel movements and the stool consistency, to reduce the number of episodes of retentive fecal incontinence, and to indirectly improve the overall quality of life.UNESP - São Paulo State University Botucatu Medical SchoolUNESP - São Paulo State University Botucatu Medical School Department of Pediatrics Pediatric Gastroenterology Hepatology and Nutrition DivisionUNESP - São Paulo State University Botucatu Medical School Department of Surgery and Orthopedics Pediatric Surgery DivisionUNESP - São Paulo State University Botucatu Medical SchoolUNESP - São Paulo State University Botucatu Medical School Department of Pediatrics Pediatric Gastroenterology Hepatology and Nutrition DivisionUNESP - São Paulo State University Botucatu Medical School Department of Surgery and Orthopedics Pediatric Surgery DivisionUniversidade Estadual Paulista (Unesp)Rego, Rebeca Mayara Padilha [UNESP]Machado, Nilton Carlos [UNESP]Carvalho, Mary de Assis [UNESP]Graffunder, Johann Souza [UNESP]Ortolan, Erika Veruska Paiva [UNESP]Lourenção, Pedro Luiz Toledo de Arruda [UNESP]2020-12-12T01:45:06Z2020-12-12T01:45:06Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlee17755http://dx.doi.org/10.1097/MD.0000000000017755Medicine, v. 98, n. 45, p. e17755-, 2019.1536-5964http://hdl.handle.net/11449/19962910.1097/MD.00000000000177552-s2.0-850747046894729603720628835Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedicineinfo:eu-repo/semantics/openAccess2024-09-03T13:46:50Zoai:repositorio.unesp.br:11449/199629Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:46:50Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
title Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
spellingShingle Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
Rego, Rebeca Mayara Padilha [UNESP]
title_short Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
title_full Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
title_fullStr Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
title_full_unstemmed Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
title_sort Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study
author Rego, Rebeca Mayara Padilha [UNESP]
author_facet Rego, Rebeca Mayara Padilha [UNESP]
Machado, Nilton Carlos [UNESP]
Carvalho, Mary de Assis [UNESP]
Graffunder, Johann Souza [UNESP]
Ortolan, Erika Veruska Paiva [UNESP]
Lourenção, Pedro Luiz Toledo de Arruda [UNESP]
author_role author
author2 Machado, Nilton Carlos [UNESP]
Carvalho, Mary de Assis [UNESP]
Graffunder, Johann Souza [UNESP]
Ortolan, Erika Veruska Paiva [UNESP]
Lourenção, Pedro Luiz Toledo de Arruda [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Rego, Rebeca Mayara Padilha [UNESP]
Machado, Nilton Carlos [UNESP]
Carvalho, Mary de Assis [UNESP]
Graffunder, Johann Souza [UNESP]
Ortolan, Erika Veruska Paiva [UNESP]
Lourenção, Pedro Luiz Toledo de Arruda [UNESP]
description INTRODUCTION: A vast majority of children with functional constipation respond to the standard medical treatment. However, a subset of patients may present with an unsatisfactory response and only minor improvement of symptoms. Transcutaneous posterior tibial nerve stimulation (PTNS) involves electrical stimulation of the posterior tibial nerve at the level of the ankle, transcutaneously through electrodes fixated on the overlying skin. Stimulation of the tibial nerve can modulate urinary and defecatory function through the stimulation of sacral nerves. Thus, transcutaneous PTNS can be considered a very promising, noninvasive, and safe method to be used in the pediatric age group. However, there is still no published study that has investigated its use in children for the treatment of intestinal constipation. This is a single-center, prospective, longitudinal, and interventional study designed to assess the applicability and clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation. Children will be submitted to daily sessions of transcutaneous PTNS for a period of 4 weeks. All children will also be invited to participate in semistructured interviews, 1 in each of the 3 assessments: 1 week before the start of the intervention; immediately after the 4 weeks of intervention; and 4 weeks after the end of the intervention period. In these interviews, the aspects related to bowel habits and quality of life will be assessed. This project aims to evaluate the clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation and the applicability of this kind of treatment. CONCLUSIONS: This protocol intended to demonstrate the efficacy of this promising method to increase the number of bowel movements and the stool consistency, to reduce the number of episodes of retentive fecal incontinence, and to indirectly improve the overall quality of life.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
2020-12-12T01:45:06Z
2020-12-12T01:45:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1097/MD.0000000000017755
Medicine, v. 98, n. 45, p. e17755-, 2019.
1536-5964
http://hdl.handle.net/11449/199629
10.1097/MD.0000000000017755
2-s2.0-85074704689
4729603720628835
url http://dx.doi.org/10.1097/MD.0000000000017755
http://hdl.handle.net/11449/199629
identifier_str_mv Medicine, v. 98, n. 45, p. e17755-, 2019.
1536-5964
10.1097/MD.0000000000017755
2-s2.0-85074704689
4729603720628835
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Medicine
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv e17755
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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