Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jevs.2012.07.001 http://hdl.handle.net/11449/74928 |
Resumo: | To investigate morphological and genomic differences between cutting and racing lines of Quarter Horses, 120 racing and 68 cutting animals of both sexes, registered at the Brazilian Association of Quarter Horse Breeders, were used. Blood samples were collected, and the following physical traits were measured: weight; height at withers; body length; length of the shank, pastern, rump, head, and neck; and chest, shank, and hoof circumference. For analysis of genomic differences, 54,602 single-nucleotide polymorphisms (SNPs) were genotyped using the Equine SNP50 BeadChip, and the quality of individual and SNP genotype data were evaluated. The fixation index, FST, was used to identify genome regions that were altered in the lines by selection. The results showed significant differences between the lines in all physical traits. Quality control led to the exclusion of four cutting animals with a call rate of <0.95. After filtering, 12,544, 13,815, and 13,370 SNPs were excluded for the whole population (n = 184), the 120 racing animals, and the 64 cutting animals, respectively. The number of informative polymorphisms detected in each line and in the whole population indicated that the Equine SNP50 BeadChip can be used in genetic studies of Quarter Horses. The fixation index, FST, identified 2,558 genome regions that may have been modified by divergent selection. © 2013 Elsevier Inc. |
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Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter HorsesGenome-wide association studyHorsePhysical traitsSNPsAnimaliaEquidaeTo investigate morphological and genomic differences between cutting and racing lines of Quarter Horses, 120 racing and 68 cutting animals of both sexes, registered at the Brazilian Association of Quarter Horse Breeders, were used. Blood samples were collected, and the following physical traits were measured: weight; height at withers; body length; length of the shank, pastern, rump, head, and neck; and chest, shank, and hoof circumference. For analysis of genomic differences, 54,602 single-nucleotide polymorphisms (SNPs) were genotyped using the Equine SNP50 BeadChip, and the quality of individual and SNP genotype data were evaluated. The fixation index, FST, was used to identify genome regions that were altered in the lines by selection. The results showed significant differences between the lines in all physical traits. Quality control led to the exclusion of four cutting animals with a call rate of <0.95. After filtering, 12,544, 13,815, and 13,370 SNPs were excluded for the whole population (n = 184), the 120 racing animals, and the 64 cutting animals, respectively. The number of informative polymorphisms detected in each line and in the whole population indicated that the Equine SNP50 BeadChip can be used in genetic studies of Quarter Horses. The fixation index, FST, identified 2,558 genome regions that may have been modified by divergent selection. © 2013 Elsevier Inc.Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Jaboticabal, Sao PauloFaculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista, Botucatu, Sao PauloFaculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Jaboticabal, Sao PauloFaculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista, Botucatu, Sao PauloUniversidade Estadual Paulista (Unesp)Meira, Camila Tângari [UNESP]Curi, Rogerio Abdallah [UNESP]Silva, Josineudson Augusto II Vasconcelos [UNESP]Monteiro Corrêa, Marcio José [UNESP]Nunes de Oliveira, Henrique [UNESP]Silveira da Mota, Marcilio Dias [UNESP]2014-05-27T11:28:45Z2014-05-27T11:28:45Z2013-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article244-249application/pdfhttp://dx.doi.org/10.1016/j.jevs.2012.07.001Journal of Equine Veterinary Science, v. 33, n. 4, p. 244-249, 2013.0737-0806http://hdl.handle.net/11449/7492810.1016/j.jevs.2012.07.001WOS:0003175343000052-s2.0-848756432232-s2.0-848661146072-s2.0-84875643223.pdf004290541571119935147134139191260000-0001-6289-0406Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Equine Veterinary Science0.8800,390info:eu-repo/semantics/openAccess2024-09-06T18:55:10Zoai:repositorio.unesp.br:11449/74928Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-06T18:55:10Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
title |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
spellingShingle |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses Meira, Camila Tângari [UNESP] Genome-wide association study Horse Physical traits SNPs Animalia Equidae |
title_short |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
title_full |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
title_fullStr |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
title_full_unstemmed |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
title_sort |
Morphological and Genomic Differences Between Cutting and Racing Lines of Quarter Horses |
author |
Meira, Camila Tângari [UNESP] |
author_facet |
Meira, Camila Tângari [UNESP] Curi, Rogerio Abdallah [UNESP] Silva, Josineudson Augusto II Vasconcelos [UNESP] Monteiro Corrêa, Marcio José [UNESP] Nunes de Oliveira, Henrique [UNESP] Silveira da Mota, Marcilio Dias [UNESP] |
author_role |
author |
author2 |
Curi, Rogerio Abdallah [UNESP] Silva, Josineudson Augusto II Vasconcelos [UNESP] Monteiro Corrêa, Marcio José [UNESP] Nunes de Oliveira, Henrique [UNESP] Silveira da Mota, Marcilio Dias [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Meira, Camila Tângari [UNESP] Curi, Rogerio Abdallah [UNESP] Silva, Josineudson Augusto II Vasconcelos [UNESP] Monteiro Corrêa, Marcio José [UNESP] Nunes de Oliveira, Henrique [UNESP] Silveira da Mota, Marcilio Dias [UNESP] |
dc.subject.por.fl_str_mv |
Genome-wide association study Horse Physical traits SNPs Animalia Equidae |
topic |
Genome-wide association study Horse Physical traits SNPs Animalia Equidae |
description |
To investigate morphological and genomic differences between cutting and racing lines of Quarter Horses, 120 racing and 68 cutting animals of both sexes, registered at the Brazilian Association of Quarter Horse Breeders, were used. Blood samples were collected, and the following physical traits were measured: weight; height at withers; body length; length of the shank, pastern, rump, head, and neck; and chest, shank, and hoof circumference. For analysis of genomic differences, 54,602 single-nucleotide polymorphisms (SNPs) were genotyped using the Equine SNP50 BeadChip, and the quality of individual and SNP genotype data were evaluated. The fixation index, FST, was used to identify genome regions that were altered in the lines by selection. The results showed significant differences between the lines in all physical traits. Quality control led to the exclusion of four cutting animals with a call rate of <0.95. After filtering, 12,544, 13,815, and 13,370 SNPs were excluded for the whole population (n = 184), the 120 racing animals, and the 64 cutting animals, respectively. The number of informative polymorphisms detected in each line and in the whole population indicated that the Equine SNP50 BeadChip can be used in genetic studies of Quarter Horses. The fixation index, FST, identified 2,558 genome regions that may have been modified by divergent selection. © 2013 Elsevier Inc. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-04-01 2014-05-27T11:28:45Z 2014-05-27T11:28:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jevs.2012.07.001 Journal of Equine Veterinary Science, v. 33, n. 4, p. 244-249, 2013. 0737-0806 http://hdl.handle.net/11449/74928 10.1016/j.jevs.2012.07.001 WOS:000317534300005 2-s2.0-84875643223 2-s2.0-84866114607 2-s2.0-84875643223.pdf 0042905415711199 3514713413919126 0000-0001-6289-0406 |
url |
http://dx.doi.org/10.1016/j.jevs.2012.07.001 http://hdl.handle.net/11449/74928 |
identifier_str_mv |
Journal of Equine Veterinary Science, v. 33, n. 4, p. 244-249, 2013. 0737-0806 10.1016/j.jevs.2012.07.001 WOS:000317534300005 2-s2.0-84875643223 2-s2.0-84866114607 2-s2.0-84875643223.pdf 0042905415711199 3514713413919126 0000-0001-6289-0406 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Equine Veterinary Science 0.880 0,390 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
244-249 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021328763224064 |