Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms

Detalhes bibliográficos
Autor(a) principal: Freitas, P. H.F.
Data de Publicação: 2021
Outros Autores: Johnson, J. S., Chen, S., Oliveira, H. R., Tiezzi, F., Lázaro, S. F. [UNESP], Huang, Y., Gu, Y., Schinckel, A. P., Brito, L. F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3389/fgene.2021.717409
http://hdl.handle.net/11449/223009
Resumo: Properly quantifying environmental heat stress (HS) is still a major challenge in livestock breeding programs, especially as adverse climatic events become more common. The definition of critical periods and climatic variables to be used as the environmental gradient is a key step for genetically evaluating heat tolerance (HTol). Therefore, the main objectives of this study were to define the best critical periods and environmental variables (ENV) to evaluate HT and estimate variance components for HT in Large White pigs. The traits included in this study were ultrasound backfat thickness (BFT), ultrasound muscle depth (MDP), piglet weaning weight (WW), off-test weight (OTW), interval between farrowing (IBF), total number of piglets born (TNB), number of piglets born alive (NBA), number of piglets born dead (NBD), number of piglets weaned (WN), and weaning to estrus interval (IWE). Seven climatic variables based on public weather station data were compared based on three criteria, including the following: (1) strongest G×E estimate as measured by the slope term, (2) ENV yielding the highest theoretical accuracy of the genomic estimated breeding values (GEBV), and (3) variable yielding the highest distribution of GEBV per ENV. Relative humidity (for BFT, MDP, NBD, WN, and WW) and maximum temperature (for OTW, TNB, NBA, IBF, and IWE) are the recommended ENV based on the analyzed criteria. The acute HS (average of 30 days before the measurement date) is the critical period recommended for OTW, BFT, and MDP in the studied population. For WN, WW, IBF, and IWE, a period ranging from 34 days prior to farrowing up to weaning is recommended. For TNB, NBA, and NBD, the critical period from 20 days prior to breeding up to 30 days into gestation is recommended. The genetic correlation values indicate that the traits were largely (WN, WW, IBF, and IWE), moderately (OTW, TNB, and NBA), or weakly (MDP, BFT, and NBD) affected by G×E interactions. This study provides relevant recommendations of critical periods and climatic gradients for several traits in order to evaluate HS in Large White pigs. These observations demonstrate that HT in Large White pigs is heritable, and genetic progress can be achieved through genetic and genomic selection.
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spelling Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Normsgenotype-by-environment interactionheat stressheat susceptiblematernal-pig lineresilienceProperly quantifying environmental heat stress (HS) is still a major challenge in livestock breeding programs, especially as adverse climatic events become more common. The definition of critical periods and climatic variables to be used as the environmental gradient is a key step for genetically evaluating heat tolerance (HTol). Therefore, the main objectives of this study were to define the best critical periods and environmental variables (ENV) to evaluate HT and estimate variance components for HT in Large White pigs. The traits included in this study were ultrasound backfat thickness (BFT), ultrasound muscle depth (MDP), piglet weaning weight (WW), off-test weight (OTW), interval between farrowing (IBF), total number of piglets born (TNB), number of piglets born alive (NBA), number of piglets born dead (NBD), number of piglets weaned (WN), and weaning to estrus interval (IWE). Seven climatic variables based on public weather station data were compared based on three criteria, including the following: (1) strongest G×E estimate as measured by the slope term, (2) ENV yielding the highest theoretical accuracy of the genomic estimated breeding values (GEBV), and (3) variable yielding the highest distribution of GEBV per ENV. Relative humidity (for BFT, MDP, NBD, WN, and WW) and maximum temperature (for OTW, TNB, NBA, IBF, and IWE) are the recommended ENV based on the analyzed criteria. The acute HS (average of 30 days before the measurement date) is the critical period recommended for OTW, BFT, and MDP in the studied population. For WN, WW, IBF, and IWE, a period ranging from 34 days prior to farrowing up to weaning is recommended. For TNB, NBA, and NBD, the critical period from 20 days prior to breeding up to 30 days into gestation is recommended. The genetic correlation values indicate that the traits were largely (WN, WW, IBF, and IWE), moderately (OTW, TNB, and NBA), or weakly (MDP, BFT, and NBD) affected by G×E interactions. This study provides relevant recommendations of critical periods and climatic gradients for several traits in order to evaluate HS in Large White pigs. These observations demonstrate that HT in Large White pigs is heritable, and genetic progress can be achieved through genetic and genomic selection.Department of Animal Sciences Purdue UniversityUSDA-ARS Livestock Behavior Research UnitFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province Sichuan Agricultural UniversityCentre for Genetic Improvement of Livestock Department of Animal Biosciences University of GuelphDepartment of Animal Science North Carolina State UniversityDepartment of Animal Science College of Agricultural and Veterinary Sciences São Paulo State University (UNESP)Smithfield Premium GeneticsDepartment of Animal Science College of Agricultural and Veterinary Sciences São Paulo State University (UNESP)Purdue UniversityUSDA-ARS Livestock Behavior Research UnitSichuan Agricultural UniversityUniversity of GuelphNorth Carolina State UniversityUniversidade Estadual Paulista (UNESP)Smithfield Premium GeneticsFreitas, P. H.F.Johnson, J. S.Chen, S.Oliveira, H. R.Tiezzi, F.Lázaro, S. F. [UNESP]Huang, Y.Gu, Y.Schinckel, A. P.Brito, L. F.2022-04-28T19:48:09Z2022-04-28T19:48:09Z2021-11-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3389/fgene.2021.717409Frontiers in Genetics, v. 12.1664-8021http://hdl.handle.net/11449/22300910.3389/fgene.2021.7174092-s2.0-85120846720Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Genetics227984info:eu-repo/semantics/openAccess2023-05-22T15:10:11Zoai:repositorio.unesp.br:11449/223009Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:07:12.009042Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
title Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
spellingShingle Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
Freitas, P. H.F.
genotype-by-environment interaction
heat stress
heat susceptible
maternal-pig line
resilience
title_short Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
title_full Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
title_fullStr Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
title_full_unstemmed Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
title_sort Definition of Environmental Variables and Critical Periods to Evaluate Heat Tolerance in Large White Pigs Based on Single-Step Genomic Reaction Norms
author Freitas, P. H.F.
author_facet Freitas, P. H.F.
Johnson, J. S.
Chen, S.
Oliveira, H. R.
Tiezzi, F.
Lázaro, S. F. [UNESP]
Huang, Y.
Gu, Y.
Schinckel, A. P.
Brito, L. F.
author_role author
author2 Johnson, J. S.
Chen, S.
Oliveira, H. R.
Tiezzi, F.
Lázaro, S. F. [UNESP]
Huang, Y.
Gu, Y.
Schinckel, A. P.
Brito, L. F.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Purdue University
USDA-ARS Livestock Behavior Research Unit
Sichuan Agricultural University
University of Guelph
North Carolina State University
Universidade Estadual Paulista (UNESP)
Smithfield Premium Genetics
dc.contributor.author.fl_str_mv Freitas, P. H.F.
Johnson, J. S.
Chen, S.
Oliveira, H. R.
Tiezzi, F.
Lázaro, S. F. [UNESP]
Huang, Y.
Gu, Y.
Schinckel, A. P.
Brito, L. F.
dc.subject.por.fl_str_mv genotype-by-environment interaction
heat stress
heat susceptible
maternal-pig line
resilience
topic genotype-by-environment interaction
heat stress
heat susceptible
maternal-pig line
resilience
description Properly quantifying environmental heat stress (HS) is still a major challenge in livestock breeding programs, especially as adverse climatic events become more common. The definition of critical periods and climatic variables to be used as the environmental gradient is a key step for genetically evaluating heat tolerance (HTol). Therefore, the main objectives of this study were to define the best critical periods and environmental variables (ENV) to evaluate HT and estimate variance components for HT in Large White pigs. The traits included in this study were ultrasound backfat thickness (BFT), ultrasound muscle depth (MDP), piglet weaning weight (WW), off-test weight (OTW), interval between farrowing (IBF), total number of piglets born (TNB), number of piglets born alive (NBA), number of piglets born dead (NBD), number of piglets weaned (WN), and weaning to estrus interval (IWE). Seven climatic variables based on public weather station data were compared based on three criteria, including the following: (1) strongest G×E estimate as measured by the slope term, (2) ENV yielding the highest theoretical accuracy of the genomic estimated breeding values (GEBV), and (3) variable yielding the highest distribution of GEBV per ENV. Relative humidity (for BFT, MDP, NBD, WN, and WW) and maximum temperature (for OTW, TNB, NBA, IBF, and IWE) are the recommended ENV based on the analyzed criteria. The acute HS (average of 30 days before the measurement date) is the critical period recommended for OTW, BFT, and MDP in the studied population. For WN, WW, IBF, and IWE, a period ranging from 34 days prior to farrowing up to weaning is recommended. For TNB, NBA, and NBD, the critical period from 20 days prior to breeding up to 30 days into gestation is recommended. The genetic correlation values indicate that the traits were largely (WN, WW, IBF, and IWE), moderately (OTW, TNB, and NBA), or weakly (MDP, BFT, and NBD) affected by G×E interactions. This study provides relevant recommendations of critical periods and climatic gradients for several traits in order to evaluate HS in Large White pigs. These observations demonstrate that HT in Large White pigs is heritable, and genetic progress can be achieved through genetic and genomic selection.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-23
2022-04-28T19:48:09Z
2022-04-28T19:48:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3389/fgene.2021.717409
Frontiers in Genetics, v. 12.
1664-8021
http://hdl.handle.net/11449/223009
10.3389/fgene.2021.717409
2-s2.0-85120846720
url http://dx.doi.org/10.3389/fgene.2021.717409
http://hdl.handle.net/11449/223009
identifier_str_mv Frontiers in Genetics, v. 12.
1664-8021
10.3389/fgene.2021.717409
2-s2.0-85120846720
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Frontiers in Genetics
227984
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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