Infection and apparent invasion of vero cells by paracoccidioides brasiliensis
Autor(a) principal: | |
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Data de Publicação: | 1994 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1080/02681219480000251 http://hdl.handle.net/11449/227861 |
Resumo: | Paracoccidioides brasiliensis probably uses many different mechanisms to establish itself in the host and cause disease. In this work, we assess an in vitro model system which uses cultured mammalian cells to investigate the virulence factors of P. brasiliensis. We were able to demonstrate an invasion process of the yeast form of this fungus in Vero cell cultures. We deduced that the overall invasive process involved three steps: adhesion, followed by invasion of individual epithelial cells and spread to adjacent cells. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
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Infection and apparent invasion of vero cells by paracoccidioides brasiliensisParacoccidioides brasiliensis probably uses many different mechanisms to establish itself in the host and cause disease. In this work, we assess an in vitro model system which uses cultured mammalian cells to investigate the virulence factors of P. brasiliensis. We were able to demonstrate an invasion process of the yeast form of this fungus in Vero cell cultures. We deduced that the overall invasive process involved three steps: adhesion, followed by invasion of individual epithelial cells and spread to adjacent cells. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, UNESP, AraraquaraDepartment of Microbiology and Immunology, Institute of Biology, UNICAMP, Campinas, São PauloDepartment of Clinical Analysis, Faculty of Pharmaceutical Sciences, UNESP, AraraquaraUniversidade Estadual Paulista (UNESP)Universidade Estadual de Campinas (UNICAMP)Mendes-Giannini, M. J.S. [UNESP]Ricci, L. C.Uemura, M. A. [UNESP]Toscano, E. [UNESP]Arns, C. W. [UNESP]2022-04-29T07:20:29Z2022-04-29T07:20:29Z1994-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article189-197http://dx.doi.org/10.1080/02681219480000251Medical Mycology, v. 32, n. 3, p. 189-197, 1994.1369-3786http://hdl.handle.net/11449/22786110.1080/026812194800002512-s2.0-84907130314Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedical Mycologyinfo:eu-repo/semantics/openAccess2024-06-21T15:19:31Zoai:repositorio.unesp.br:11449/227861Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:59:19.527703Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
title |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
spellingShingle |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis Mendes-Giannini, M. J.S. [UNESP] |
title_short |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
title_full |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
title_fullStr |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
title_full_unstemmed |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
title_sort |
Infection and apparent invasion of vero cells by paracoccidioides brasiliensis |
author |
Mendes-Giannini, M. J.S. [UNESP] |
author_facet |
Mendes-Giannini, M. J.S. [UNESP] Ricci, L. C. Uemura, M. A. [UNESP] Toscano, E. [UNESP] Arns, C. W. [UNESP] |
author_role |
author |
author2 |
Ricci, L. C. Uemura, M. A. [UNESP] Toscano, E. [UNESP] Arns, C. W. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Mendes-Giannini, M. J.S. [UNESP] Ricci, L. C. Uemura, M. A. [UNESP] Toscano, E. [UNESP] Arns, C. W. [UNESP] |
description |
Paracoccidioides brasiliensis probably uses many different mechanisms to establish itself in the host and cause disease. In this work, we assess an in vitro model system which uses cultured mammalian cells to investigate the virulence factors of P. brasiliensis. We were able to demonstrate an invasion process of the yeast form of this fungus in Vero cell cultures. We deduced that the overall invasive process involved three steps: adhesion, followed by invasion of individual epithelial cells and spread to adjacent cells. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-01-01 2022-04-29T07:20:29Z 2022-04-29T07:20:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1080/02681219480000251 Medical Mycology, v. 32, n. 3, p. 189-197, 1994. 1369-3786 http://hdl.handle.net/11449/227861 10.1080/02681219480000251 2-s2.0-84907130314 |
url |
http://dx.doi.org/10.1080/02681219480000251 http://hdl.handle.net/11449/227861 |
identifier_str_mv |
Medical Mycology, v. 32, n. 3, p. 189-197, 1994. 1369-3786 10.1080/02681219480000251 2-s2.0-84907130314 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Medical Mycology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
189-197 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129479086702592 |