Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Tamiris Fagundes [UNESP]
Data de Publicação: 2020
Outros Autores: Benitez, Aline do Nascimento, Seva, Anaia da Paixao, Okamura, Lucas Hidenori [UNESP], Galvao, Andre Batista [UNESP], Gomes, Jancarlo Ferreira, Saraiva Bresciani, Katia Denise [UNESP], Cardoso, Tereza Cristina [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/0037-8682-0525-2019
http://hdl.handle.net/11449/196932
Resumo: Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters.
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spelling Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian areaDual Path PlatformKernel estimationLeishmaniaRisk factorsZoonosesIntroduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters.Univ Estadual Paulista, Fac Med Vet, Programa Posgrad Ciencia Anim, Aracatuba, SP, BrazilUniv Estadual Campinas, Programa Posgrad Saude Crianca & Adolescente, Campinas, SP, BrazilUniv Sao Paulo, Dept Med Vet Prevent & Ciencia Anim, Sao Paulo, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Dept Prod & Saude Anim, Aracatuba, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Programa Posgrad Ciencia Anim, Aracatuba, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Dept Prod & Saude Anim, Aracatuba, SP, BrazilSoc Brasileira Medicina TropicalUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Universidade de São Paulo (USP)Rodrigues, Tamiris Fagundes [UNESP]Benitez, Aline do NascimentoSeva, Anaia da PaixaoOkamura, Lucas Hidenori [UNESP]Galvao, Andre Batista [UNESP]Gomes, Jancarlo FerreiraSaraiva Bresciani, Katia Denise [UNESP]Cardoso, Tereza Cristina [UNESP]2020-12-10T20:00:46Z2020-12-10T20:00:46Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://dx.doi.org/10.1590/0037-8682-0525-2019Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020.0037-8682http://hdl.handle.net/11449/19693210.1590/0037-8682-0525-2019S0037-86822020000100324WOS:000537090000001S0037-86822020000100324.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Da Sociedade Brasileira De Medicina Tropicalinfo:eu-repo/semantics/openAccess2024-09-04T19:15:12Zoai:repositorio.unesp.br:11449/196932Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T19:15:12Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
title Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
spellingShingle Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
Rodrigues, Tamiris Fagundes [UNESP]
Dual Path Platform
Kernel estimation
Leishmania
Risk factors
Zoonoses
title_short Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
title_full Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
title_fullStr Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
title_full_unstemmed Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
title_sort Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
author Rodrigues, Tamiris Fagundes [UNESP]
author_facet Rodrigues, Tamiris Fagundes [UNESP]
Benitez, Aline do Nascimento
Seva, Anaia da Paixao
Okamura, Lucas Hidenori [UNESP]
Galvao, Andre Batista [UNESP]
Gomes, Jancarlo Ferreira
Saraiva Bresciani, Katia Denise [UNESP]
Cardoso, Tereza Cristina [UNESP]
author_role author
author2 Benitez, Aline do Nascimento
Seva, Anaia da Paixao
Okamura, Lucas Hidenori [UNESP]
Galvao, Andre Batista [UNESP]
Gomes, Jancarlo Ferreira
Saraiva Bresciani, Katia Denise [UNESP]
Cardoso, Tereza Cristina [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Estadual de Campinas (UNICAMP)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Rodrigues, Tamiris Fagundes [UNESP]
Benitez, Aline do Nascimento
Seva, Anaia da Paixao
Okamura, Lucas Hidenori [UNESP]
Galvao, Andre Batista [UNESP]
Gomes, Jancarlo Ferreira
Saraiva Bresciani, Katia Denise [UNESP]
Cardoso, Tereza Cristina [UNESP]
dc.subject.por.fl_str_mv Dual Path Platform
Kernel estimation
Leishmania
Risk factors
Zoonoses
topic Dual Path Platform
Kernel estimation
Leishmania
Risk factors
Zoonoses
description Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-10T20:00:46Z
2020-12-10T20:00:46Z
2020-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/0037-8682-0525-2019
Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020.
0037-8682
http://hdl.handle.net/11449/196932
10.1590/0037-8682-0525-2019
S0037-86822020000100324
WOS:000537090000001
S0037-86822020000100324.pdf
url http://dx.doi.org/10.1590/0037-8682-0525-2019
http://hdl.handle.net/11449/196932
identifier_str_mv Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020.
0037-8682
10.1590/0037-8682-0525-2019
S0037-86822020000100324
WOS:000537090000001
S0037-86822020000100324.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Da Sociedade Brasileira De Medicina Tropical
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
dc.publisher.none.fl_str_mv Soc Brasileira Medicina Tropical
publisher.none.fl_str_mv Soc Brasileira Medicina Tropical
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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