Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/0037-8682-0525-2019 http://hdl.handle.net/11449/196932 |
Resumo: | Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters. |
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Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian areaDual Path PlatformKernel estimationLeishmaniaRisk factorsZoonosesIntroduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters.Univ Estadual Paulista, Fac Med Vet, Programa Posgrad Ciencia Anim, Aracatuba, SP, BrazilUniv Estadual Campinas, Programa Posgrad Saude Crianca & Adolescente, Campinas, SP, BrazilUniv Sao Paulo, Dept Med Vet Prevent & Ciencia Anim, Sao Paulo, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Dept Prod & Saude Anim, Aracatuba, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Programa Posgrad Ciencia Anim, Aracatuba, SP, BrazilUniv Estadual Paulista, Fac Med Vet, Dept Prod & Saude Anim, Aracatuba, SP, BrazilSoc Brasileira Medicina TropicalUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Universidade de São Paulo (USP)Rodrigues, Tamiris Fagundes [UNESP]Benitez, Aline do NascimentoSeva, Anaia da PaixaoOkamura, Lucas Hidenori [UNESP]Galvao, Andre Batista [UNESP]Gomes, Jancarlo FerreiraSaraiva Bresciani, Katia Denise [UNESP]Cardoso, Tereza Cristina [UNESP]2020-12-10T20:00:46Z2020-12-10T20:00:46Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://dx.doi.org/10.1590/0037-8682-0525-2019Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020.0037-8682http://hdl.handle.net/11449/19693210.1590/0037-8682-0525-2019S0037-86822020000100324WOS:000537090000001S0037-86822020000100324.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Da Sociedade Brasileira De Medicina Tropicalinfo:eu-repo/semantics/openAccess2024-09-04T19:15:12Zoai:repositorio.unesp.br:11449/196932Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T19:15:12Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
title |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
spellingShingle |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area Rodrigues, Tamiris Fagundes [UNESP] Dual Path Platform Kernel estimation Leishmania Risk factors Zoonoses |
title_short |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
title_full |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
title_fullStr |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
title_full_unstemmed |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
title_sort |
Spatial and seroepidemiology of canine visceral leishmaniasis in an endemic Southeast Brazilian area |
author |
Rodrigues, Tamiris Fagundes [UNESP] |
author_facet |
Rodrigues, Tamiris Fagundes [UNESP] Benitez, Aline do Nascimento Seva, Anaia da Paixao Okamura, Lucas Hidenori [UNESP] Galvao, Andre Batista [UNESP] Gomes, Jancarlo Ferreira Saraiva Bresciani, Katia Denise [UNESP] Cardoso, Tereza Cristina [UNESP] |
author_role |
author |
author2 |
Benitez, Aline do Nascimento Seva, Anaia da Paixao Okamura, Lucas Hidenori [UNESP] Galvao, Andre Batista [UNESP] Gomes, Jancarlo Ferreira Saraiva Bresciani, Katia Denise [UNESP] Cardoso, Tereza Cristina [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Rodrigues, Tamiris Fagundes [UNESP] Benitez, Aline do Nascimento Seva, Anaia da Paixao Okamura, Lucas Hidenori [UNESP] Galvao, Andre Batista [UNESP] Gomes, Jancarlo Ferreira Saraiva Bresciani, Katia Denise [UNESP] Cardoso, Tereza Cristina [UNESP] |
dc.subject.por.fl_str_mv |
Dual Path Platform Kernel estimation Leishmania Risk factors Zoonoses |
topic |
Dual Path Platform Kernel estimation Leishmania Risk factors Zoonoses |
description |
Introduction: Canine visceral leishmaniasis (CVL) is a public health problem, and its prevalence is associated with the coexistence of vectors and reservoirs. CVL is a protozoonosis caused by Leishmania infantum that is endemic in the southeast region of Brazil. Thus, vector and canine reservoir control strategies are needed to reduce its burden. This study aimed to verify the CVL seroprevalence and epidemiology in a municipality in Southeast Brazil to initiate disease control strategies. Methods: A total of 833 dogs were subjected to Dual Path Platform (DPP) testing and enzyme-linked immunosorbent assays. For seropositive dogs, epidemiological aspects were investigated using a questionnaire and a global position system. The data were submitted to simple logistic regression, kernel estimation, and Bernoulli spatial scan statistical analysis. Results: The overall CVL-confirmed seroprevalence was 16.08%. The 28.93% in the DPP screening test was associated with dogs maintained in backyards with trees, shade, animal and/or bird feces, and contact with other dogs and cats, with sick dogs showing the highest chances of infection (odds ratio, 2.6; 95% confidence interval, 2.38-1.98), especially in residences with elderly people. A spatial analysis identified two hotspot regions and detected two clusters in the study area. Conclusions: Our results demonstrated that residences with elderly people and the presence of trees, shade, feces, and pet dogs and cats increased an individual's risk of developing CVL. The major regions where preventive strategies for leishmaniasis were to be initiated in the endemic area were identified in two clusters. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-10T20:00:46Z 2020-12-10T20:00:46Z 2020-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/0037-8682-0525-2019 Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020. 0037-8682 http://hdl.handle.net/11449/196932 10.1590/0037-8682-0525-2019 S0037-86822020000100324 WOS:000537090000001 S0037-86822020000100324.pdf |
url |
http://dx.doi.org/10.1590/0037-8682-0525-2019 http://hdl.handle.net/11449/196932 |
identifier_str_mv |
Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 53, 7 p., 2020. 0037-8682 10.1590/0037-8682-0525-2019 S0037-86822020000100324 WOS:000537090000001 S0037-86822020000100324.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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Revista Da Sociedade Brasileira De Medicina Tropical |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
7 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Brasileira Medicina Tropical |
publisher.none.fl_str_mv |
Soc Brasileira Medicina Tropical |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
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UNESP |
reponame_str |
Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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