American visceral Leishmaniasis: a case report

Detalhes bibliográficos
Autor(a) principal: Langoni, H. [UNESP]
Data de Publicação: 2005
Outros Autores: Lucheis, S. B. [UNESP], Da Silva, R. C. [UNESP], Castro, A. P. B. [UNESP], Paes, A. C. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992005000300012
http://hdl.handle.net/11449/211859
Resumo: Visceral leishmaniasis is a zoonotic disease caused by parasites of the Leishmania genus. Dog is the major source of infection to man, especially in urban areas. The authors report a case of visceral leishmaniasis in a pit bull female dog from Bocaina, São Paulo, Brazil. The animal presented clinical signs compatible with leishmaniasis, including skin lesions in the body and partial damage of the external ears. The indirect fluorescent antibody test (IFAT) demonstrated a titer of 1280, and promastigote forms of Leishmania sp were isolated by the culture of bone marrow puncture. Cytological analysis of the lymph node and smear of the bone marrow puncture revealed macrophages containing amastigote forms of Leishmania sp in their inner region. The test of Polymerase Chain Reaction (PCR) utilized the primers LINR4 and LIN19, which amplify 720 base pairs, specific for Leishmania sp. The authors discuss the importance of techniques for a quick and precise diagnosis to this serious zoonosis with great impact in animal and public health.
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spelling American visceral Leishmaniasis: a case reportLeishmaniazoonosisdogdiagnosishemocultureserologypolymerase chain reaction (PCR)Visceral leishmaniasis is a zoonotic disease caused by parasites of the Leishmania genus. Dog is the major source of infection to man, especially in urban areas. The authors report a case of visceral leishmaniasis in a pit bull female dog from Bocaina, São Paulo, Brazil. The animal presented clinical signs compatible with leishmaniasis, including skin lesions in the body and partial damage of the external ears. The indirect fluorescent antibody test (IFAT) demonstrated a titer of 1280, and promastigote forms of Leishmania sp were isolated by the culture of bone marrow puncture. Cytological analysis of the lymph node and smear of the bone marrow puncture revealed macrophages containing amastigote forms of Leishmania sp in their inner region. The test of Polymerase Chain Reaction (PCR) utilized the primers LINR4 and LIN19, which amplify 720 base pairs, specific for Leishmania sp. The authors discuss the importance of techniques for a quick and precise diagnosis to this serious zoonosis with great impact in animal and public health.Universidade Estadual Paulista, School of Veterinary Medicine and Animal HusbandryUniversidade Estadual Paulista, School of Veterinary Medicine and Animal HusbandryCentro de Estudos de Venenos e Animais PeçonhentosUniversidade Estadual Paulista (Unesp)Langoni, H. [UNESP]Lucheis, S. B. [UNESP]Da Silva, R. C. [UNESP]Castro, A. P. B. [UNESP]Paes, A. C. [UNESP]2021-07-14T10:30:44Z2021-07-14T10:30:44Z2005-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article361-372application/pdfhttp://dx.doi.org/10.1590/S1678-91992005000300012Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 3, p. 361-372, 2005.1678-9199http://hdl.handle.net/11449/21185910.1590/S1678-91992005000300012S1678-91992005000300012S1678-91992005000300012.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins including Tropical Diseasesinfo:eu-repo/semantics/openAccess2023-10-13T06:07:02Zoai:repositorio.unesp.br:11449/211859Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462023-10-13T06:07:02Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv American visceral Leishmaniasis: a case report
title American visceral Leishmaniasis: a case report
spellingShingle American visceral Leishmaniasis: a case report
Langoni, H. [UNESP]
Leishmania
zoonosis
dog
diagnosis
hemoculture
serology
polymerase chain reaction (PCR)
title_short American visceral Leishmaniasis: a case report
title_full American visceral Leishmaniasis: a case report
title_fullStr American visceral Leishmaniasis: a case report
title_full_unstemmed American visceral Leishmaniasis: a case report
title_sort American visceral Leishmaniasis: a case report
author Langoni, H. [UNESP]
author_facet Langoni, H. [UNESP]
Lucheis, S. B. [UNESP]
Da Silva, R. C. [UNESP]
Castro, A. P. B. [UNESP]
Paes, A. C. [UNESP]
author_role author
author2 Lucheis, S. B. [UNESP]
Da Silva, R. C. [UNESP]
Castro, A. P. B. [UNESP]
Paes, A. C. [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Langoni, H. [UNESP]
Lucheis, S. B. [UNESP]
Da Silva, R. C. [UNESP]
Castro, A. P. B. [UNESP]
Paes, A. C. [UNESP]
dc.subject.por.fl_str_mv Leishmania
zoonosis
dog
diagnosis
hemoculture
serology
polymerase chain reaction (PCR)
topic Leishmania
zoonosis
dog
diagnosis
hemoculture
serology
polymerase chain reaction (PCR)
description Visceral leishmaniasis is a zoonotic disease caused by parasites of the Leishmania genus. Dog is the major source of infection to man, especially in urban areas. The authors report a case of visceral leishmaniasis in a pit bull female dog from Bocaina, São Paulo, Brazil. The animal presented clinical signs compatible with leishmaniasis, including skin lesions in the body and partial damage of the external ears. The indirect fluorescent antibody test (IFAT) demonstrated a titer of 1280, and promastigote forms of Leishmania sp were isolated by the culture of bone marrow puncture. Cytological analysis of the lymph node and smear of the bone marrow puncture revealed macrophages containing amastigote forms of Leishmania sp in their inner region. The test of Polymerase Chain Reaction (PCR) utilized the primers LINR4 and LIN19, which amplify 720 base pairs, specific for Leishmania sp. The authors discuss the importance of techniques for a quick and precise diagnosis to this serious zoonosis with great impact in animal and public health.
publishDate 2005
dc.date.none.fl_str_mv 2005-09
2021-07-14T10:30:44Z
2021-07-14T10:30:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992005000300012
Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 3, p. 361-372, 2005.
1678-9199
http://hdl.handle.net/11449/211859
10.1590/S1678-91992005000300012
S1678-91992005000300012
S1678-91992005000300012.pdf
url http://dx.doi.org/10.1590/S1678-91992005000300012
http://hdl.handle.net/11449/211859
identifier_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 3, p. 361-372, 2005.
1678-9199
10.1590/S1678-91992005000300012
S1678-91992005000300012
S1678-91992005000300012.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 361-372
application/pdf
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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