Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.surgicalcosmetic.org.br/detalhe-artigo/25/Ensaio-randomizado--duplo-cego-e-controlado-de-anestesia-topica-induzida-por-iontoforese-de-lidocaina http://hdl.handle.net/11449/71453 |
Resumo: | Introduction: Needle infi ltration of local anesthetic is a painful procedure, thus, a topical anesthetic is a comfortable alternative; however, it is diffi cult to deliver transcutaneous polar drugs. Iontophoresis is a noninvasive technique that uses electrical current for releasing electrically charged drugs through biological membranes. Objective: To evaluate the anesthesia induced by iontophoresis of lidocaine for a standardized painful stimulus. Material and methods: Randomized, controlled, double-blind study, involving 10 volunteers under the anesthetic effects of topical application of lidocaine gel 2% and noradrenaline 1:50,000, with or without iontophoresis of 1.85 milliamps for 13 minutes. Pain sensitivity was evaluated by the prick of a 21G needle in the arms posterior region, using a visual numerical scale. Results: Patients mean age was 50.8 ± 11.4 years. Nine of them were women. All had previously received infi ltrative anesthesia. Iontophoresis was well tolerated by volunteers. The median pain scores were 0 and 3 for the arm that received the iontophoresis and for the one that did not receive, respectively (p < 0.01). Conclusion: The anesthetic effect in the region subjected to iontophoresis suggests an effi cient and comfortable method for promoting local anesthesia in the surgical approach of pediatric, hyperalgic, or needlephobic patients. |
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Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaínaRandomized, double-blind, controlled topical anesthesia induced by iontophoresis of lidocaineAmbulatory surgery proceduresAnesthesiaIontophoresisLidocaineIntroduction: Needle infi ltration of local anesthetic is a painful procedure, thus, a topical anesthetic is a comfortable alternative; however, it is diffi cult to deliver transcutaneous polar drugs. Iontophoresis is a noninvasive technique that uses electrical current for releasing electrically charged drugs through biological membranes. Objective: To evaluate the anesthesia induced by iontophoresis of lidocaine for a standardized painful stimulus. Material and methods: Randomized, controlled, double-blind study, involving 10 volunteers under the anesthetic effects of topical application of lidocaine gel 2% and noradrenaline 1:50,000, with or without iontophoresis of 1.85 milliamps for 13 minutes. Pain sensitivity was evaluated by the prick of a 21G needle in the arms posterior region, using a visual numerical scale. Results: Patients mean age was 50.8 ± 11.4 years. Nine of them were women. All had previously received infi ltrative anesthesia. Iontophoresis was well tolerated by volunteers. The median pain scores were 0 and 3 for the arm that received the iontophoresis and for the one that did not receive, respectively (p < 0.01). Conclusion: The anesthetic effect in the region subjected to iontophoresis suggests an effi cient and comfortable method for promoting local anesthesia in the surgical approach of pediatric, hyperalgic, or needlephobic patients.Médico dermatologista Fundação Pró-HansenDepartamento de Dermatologia da FMB UnespDepartamento de Dermatologia da FMB UnespMédico dermatologista Fundação Pró-HansenUniversidade Estadual Paulista (Unesp)Schmitt, Juliano Vilaverde [UNESP]Miot, Hélio Amante [UNESP]2014-05-27T11:24:34Z2014-05-27T11:24:34Z2009-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article112-114application/pdfhttp://www.surgicalcosmetic.org.br/detalhe-artigo/25/Ensaio-randomizado--duplo-cego-e-controlado-de-anestesia-topica-induzida-por-iontoforese-de-lidocainaSurgical and Cosmetic Dermatology, v. 1, n. 3, p. 112-114, 2009.1984-55101984-8773http://hdl.handle.net/11449/714532-s2.0-800547069882-s2.0-80054706988.pdf2543633050941005Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporSurgical and Cosmetic Dermatology0,1410,141info:eu-repo/semantics/openAccess2024-08-14T18:45:45Zoai:repositorio.unesp.br:11449/71453Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:45:45Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína Randomized, double-blind, controlled topical anesthesia induced by iontophoresis of lidocaine |
title |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
spellingShingle |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína Schmitt, Juliano Vilaverde [UNESP] Ambulatory surgery procedures Anesthesia Iontophoresis Lidocaine |
title_short |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
title_full |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
title_fullStr |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
title_full_unstemmed |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
title_sort |
Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína |
author |
Schmitt, Juliano Vilaverde [UNESP] |
author_facet |
Schmitt, Juliano Vilaverde [UNESP] Miot, Hélio Amante [UNESP] |
author_role |
author |
author2 |
Miot, Hélio Amante [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Médico dermatologista Fundação Pró-Hansen Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Schmitt, Juliano Vilaverde [UNESP] Miot, Hélio Amante [UNESP] |
dc.subject.por.fl_str_mv |
Ambulatory surgery procedures Anesthesia Iontophoresis Lidocaine |
topic |
Ambulatory surgery procedures Anesthesia Iontophoresis Lidocaine |
description |
Introduction: Needle infi ltration of local anesthetic is a painful procedure, thus, a topical anesthetic is a comfortable alternative; however, it is diffi cult to deliver transcutaneous polar drugs. Iontophoresis is a noninvasive technique that uses electrical current for releasing electrically charged drugs through biological membranes. Objective: To evaluate the anesthesia induced by iontophoresis of lidocaine for a standardized painful stimulus. Material and methods: Randomized, controlled, double-blind study, involving 10 volunteers under the anesthetic effects of topical application of lidocaine gel 2% and noradrenaline 1:50,000, with or without iontophoresis of 1.85 milliamps for 13 minutes. Pain sensitivity was evaluated by the prick of a 21G needle in the arms posterior region, using a visual numerical scale. Results: Patients mean age was 50.8 ± 11.4 years. Nine of them were women. All had previously received infi ltrative anesthesia. Iontophoresis was well tolerated by volunteers. The median pain scores were 0 and 3 for the arm that received the iontophoresis and for the one that did not receive, respectively (p < 0.01). Conclusion: The anesthetic effect in the region subjected to iontophoresis suggests an effi cient and comfortable method for promoting local anesthesia in the surgical approach of pediatric, hyperalgic, or needlephobic patients. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12-01 2014-05-27T11:24:34Z 2014-05-27T11:24:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.surgicalcosmetic.org.br/detalhe-artigo/25/Ensaio-randomizado--duplo-cego-e-controlado-de-anestesia-topica-induzida-por-iontoforese-de-lidocaina Surgical and Cosmetic Dermatology, v. 1, n. 3, p. 112-114, 2009. 1984-5510 1984-8773 http://hdl.handle.net/11449/71453 2-s2.0-80054706988 2-s2.0-80054706988.pdf 2543633050941005 |
url |
http://www.surgicalcosmetic.org.br/detalhe-artigo/25/Ensaio-randomizado--duplo-cego-e-controlado-de-anestesia-topica-induzida-por-iontoforese-de-lidocaina http://hdl.handle.net/11449/71453 |
identifier_str_mv |
Surgical and Cosmetic Dermatology, v. 1, n. 3, p. 112-114, 2009. 1984-5510 1984-8773 2-s2.0-80054706988 2-s2.0-80054706988.pdf 2543633050941005 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Surgical and Cosmetic Dermatology 0,141 0,141 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
112-114 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128152422055936 |