Ensaio randomizado, duplo-cego e controlado de anestesia tópica induzida por iontoforese de lidocaína

• Autor(a) principal: Schmitt, Juliano Vilaverde [UNESP]
• Data de Publicação: 2009
• Outros Autores: Miot, Hélio Amante [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.surgicalcosmetic.org.br/detalhe-artigo/25/Ensaio-randomizado--duplo-cego-e-controlado-de-anestesia-topica-induzida-por-iontoforese-de-lidocaina; http://hdl.handle.net/11449/71453
• topic: Ambulatory surgery procedures; Anesthesia; Iontophoresis; Lidocaine

Introduction: Needle infi ltration of local anesthetic is a painful procedure, thus, a topical anesthetic is a comfortable alternative; however, it is diffi cult to deliver transcutaneous polar drugs. Iontophoresis is a noninvasive technique that uses electrical current for releasing electrically charged drugs through biological membranes. Objective: To evaluate the anesthesia induced by iontophoresis of lidocaine for a standardized painful stimulus. Material and methods: Randomized, controlled, double-blind study, involving 10 volunteers under the anesthetic effects of topical application of lidocaine gel 2% and noradrenaline 1:50,000, with or without iontophoresis of 1.85 milliamps for 13 minutes. Pain sensitivity was evaluated by the prick of a 21G needle in the arms posterior region, using a visual numerical scale. Results: Patients mean age was 50.8 ± 11.4 years. Nine of them were women. All had previously received infi ltrative anesthesia. Iontophoresis was well tolerated by volunteers. The median pain scores were 0 and 3 for the arm that received the iontophoresis and for the one that did not receive, respectively (p < 0.01). Conclusion: The anesthetic effect in the region subjected to iontophoresis suggests an effi cient and comfortable method for promoting local anesthesia in the surgical approach of pediatric, hyperalgic, or needlephobic patients.