Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case

Detalhes bibliográficos
Autor(a) principal: Alves, M. G. Oliveira [UNESP]
Data de Publicação: 2014
Outros Autores: De Sousa, S. C O M, Carvalho, Y. R. [UNESP], Almeida, J. D. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/171741
Resumo: Introduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation.
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spelling Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral caseIntroduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation.Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP - Univ Estadual Paulista, São José dos CamposDepartment of Oral Pathology, School of Dentistry, University of São PauloDepartment of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP - Univ Estadual Paulista, São José dos CamposUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Alves, M. G. Oliveira [UNESP]De Sousa, S. C O MCarvalho, Y. R. [UNESP]Almeida, J. D. [UNESP]2018-12-11T16:56:49Z2018-12-11T16:56:49Z2014-05-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHead and Neck Oncology, v. 6, n. 2, 2014.1758-3284http://hdl.handle.net/11449/1717412-s2.0-84919460493Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengHead and Neck Oncology0,104info:eu-repo/semantics/openAccess2021-10-23T15:16:36Zoai:repositorio.unesp.br:11449/171741Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:58:49.704291Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
title Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
spellingShingle Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
Alves, M. G. Oliveira [UNESP]
title_short Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
title_full Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
title_fullStr Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
title_full_unstemmed Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
title_sort Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
author Alves, M. G. Oliveira [UNESP]
author_facet Alves, M. G. Oliveira [UNESP]
De Sousa, S. C O M
Carvalho, Y. R. [UNESP]
Almeida, J. D. [UNESP]
author_role author
author2 De Sousa, S. C O M
Carvalho, Y. R. [UNESP]
Almeida, J. D. [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Alves, M. G. Oliveira [UNESP]
De Sousa, S. C O M
Carvalho, Y. R. [UNESP]
Almeida, J. D. [UNESP]
description Introduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation.
publishDate 2014
dc.date.none.fl_str_mv 2014-05-03
2018-12-11T16:56:49Z
2018-12-11T16:56:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv Head and Neck Oncology, v. 6, n. 2, 2014.
1758-3284
http://hdl.handle.net/11449/171741
2-s2.0-84919460493
identifier_str_mv Head and Neck Oncology, v. 6, n. 2, 2014.
1758-3284
2-s2.0-84919460493
url http://hdl.handle.net/11449/171741
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0,104
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reponame:Repositório Institucional da UNESP
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