Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/171741 |
Resumo: | Introduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation. |
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Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral caseIntroduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation.Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP - Univ Estadual Paulista, São José dos CamposDepartment of Oral Pathology, School of Dentistry, University of São PauloDepartment of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP - Univ Estadual Paulista, São José dos CamposUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Alves, M. G. Oliveira [UNESP]De Sousa, S. C O MCarvalho, Y. R. [UNESP]Almeida, J. D. [UNESP]2018-12-11T16:56:49Z2018-12-11T16:56:49Z2014-05-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHead and Neck Oncology, v. 6, n. 2, 2014.1758-3284http://hdl.handle.net/11449/1717412-s2.0-84919460493Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengHead and Neck Oncology0,104info:eu-repo/semantics/openAccess2021-10-23T15:16:36Zoai:repositorio.unesp.br:11449/171741Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:58:49.704291Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
title |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
spellingShingle |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case Alves, M. G. Oliveira [UNESP] |
title_short |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
title_full |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
title_fullStr |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
title_full_unstemmed |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
title_sort |
Primary signet-ring squamous cell carcinoma of the oral cavity: The first intraoral case |
author |
Alves, M. G. Oliveira [UNESP] |
author_facet |
Alves, M. G. Oliveira [UNESP] De Sousa, S. C O M Carvalho, Y. R. [UNESP] Almeida, J. D. [UNESP] |
author_role |
author |
author2 |
De Sousa, S. C O M Carvalho, Y. R. [UNESP] Almeida, J. D. [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Alves, M. G. Oliveira [UNESP] De Sousa, S. C O M Carvalho, Y. R. [UNESP] Almeida, J. D. [UNESP] |
description |
Introduction: The aim of this paper was to report a case of primary signet-ring squamous cell carcinoma in the floor of the mouth and highlight the importance of complete oral examination. Case report: We report the case of a 54-year-old man who complained of pain and difficulty to open the mouth. The patient presented to the outpatient clinic after he had visited 18 dentists without any definite diagnosis. Oral examination showed a mass in the submandibular gland and an ultrasound revealed an expansive lesion. Histopathological analysis showed the presence of a tumour infiltrating adjacent tissue with groups of cells exhibiting a signet-ring appearance. PAS and mucicarmine was negative. Immunohistochemical staining for CK7 and EMA was strongly positive and Ki67 staining was weakly positive. The lesion was completely submucosal and no ulceration was observed. Conclusion: This case of signet-ring cell SCC originating from the excretory duct of the submandibular gland represents a rare variant of oral SCC and highlights the importance of complete oral examination, including palpation. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-05-03 2018-12-11T16:56:49Z 2018-12-11T16:56:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Head and Neck Oncology, v. 6, n. 2, 2014. 1758-3284 http://hdl.handle.net/11449/171741 2-s2.0-84919460493 |
identifier_str_mv |
Head and Neck Oncology, v. 6, n. 2, 2014. 1758-3284 2-s2.0-84919460493 |
url |
http://hdl.handle.net/11449/171741 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Head and Neck Oncology 0,104 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129145654214656 |