Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin

Detalhes bibliográficos
Autor(a) principal: Borghesan, Alexandre C. [UNESP]
Data de Publicação: 2018
Outros Autores: Barbosa, Roberta G. [UNESP], Cerqueira, Nereide F. [UNESP], Takahira, Regina K. [UNESP], Vulcano, Luiz C. [UNESP], Alves, Ana Liz G. [UNESP], Watanabe, Marcos J. [UNESP], Alonso, Juliana M. [UNESP], Rollo, Hamilton A. [UNESP], Hussni, Carlos A. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.jevs.2018.06.010
http://hdl.handle.net/11449/176555
Resumo: Jugular thrombophlebitis is a major vascular disease in horses and can lead even to death. Heparin is used to inhibit thrombus growth in humans. The aim of this experiment was to evaluate heparin administration in horses with induced thrombophlebitis. Ten animals were subjected to experimental thrombophlebitis and divided into a control group and heparin group (HG). The HG received heparin (150 IU/kg) for 10 days. Coagulation tests, ultrasound, and venography were performed before and after thrombophlebitis induction. Comparing the HG and control group, a break in the growth of the thrombus after the start of administration of the drug and a decrease in the length of the thrombus with the appearance of flow down the sides of the cranial portion of the thrombus were observed. However, after discontinuation of heparin, fast daily growth of the thrombus and decreased blood flow to the side were observed.
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spelling Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With HeparinActivated partial thromboplastin timeHorsesThrombosisUltrasoundVenographyJugular thrombophlebitis is a major vascular disease in horses and can lead even to death. Heparin is used to inhibit thrombus growth in humans. The aim of this experiment was to evaluate heparin administration in horses with induced thrombophlebitis. Ten animals were subjected to experimental thrombophlebitis and divided into a control group and heparin group (HG). The HG received heparin (150 IU/kg) for 10 days. Coagulation tests, ultrasound, and venography were performed before and after thrombophlebitis induction. Comparing the HG and control group, a break in the growth of the thrombus after the start of administration of the drug and a decrease in the length of the thrombus with the appearance of flow down the sides of the cranial portion of the thrombus were observed. However, after discontinuation of heparin, fast daily growth of the thrombus and decreased blood flow to the side were observed.Department of Veterinary Surgery and Anesthesiology School of Veterinary Medicine and Animal Science São Paulo State University (Unesp)Department of Surgery Medical School São Paulo State University (Unesp)Department of Veterinary Surgery and Anesthesiology School of Veterinary Medicine and Animal Science São Paulo State University (Unesp)Department of Surgery Medical School São Paulo State University (Unesp)Universidade Estadual Paulista (Unesp)Borghesan, Alexandre C. [UNESP]Barbosa, Roberta G. [UNESP]Cerqueira, Nereide F. [UNESP]Takahira, Regina K. [UNESP]Vulcano, Luiz C. [UNESP]Alves, Ana Liz G. [UNESP]Watanabe, Marcos J. [UNESP]Alonso, Juliana M. [UNESP]Rollo, Hamilton A. [UNESP]Hussni, Carlos A. [UNESP]2018-12-11T17:21:20Z2018-12-11T17:21:20Z2018-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article59-65application/pdfhttp://dx.doi.org/10.1016/j.jevs.2018.06.010Journal of Equine Veterinary Science, v. 69, p. 59-65.0737-0806http://hdl.handle.net/11449/17655510.1016/j.jevs.2018.06.0102-s2.0-850495082592-s2.0-85049508259.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Equine Veterinary Science0,390info:eu-repo/semantics/openAccess2024-01-14T06:19:18Zoai:repositorio.unesp.br:11449/176555Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:56:01.820515Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
title Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
spellingShingle Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
Borghesan, Alexandre C. [UNESP]
Activated partial thromboplastin time
Horses
Thrombosis
Ultrasound
Venography
title_short Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
title_full Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
title_fullStr Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
title_full_unstemmed Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
title_sort Evaluation of Experimental Jugular Thrombophlebitis in Horses Treated With Heparin
author Borghesan, Alexandre C. [UNESP]
author_facet Borghesan, Alexandre C. [UNESP]
Barbosa, Roberta G. [UNESP]
Cerqueira, Nereide F. [UNESP]
Takahira, Regina K. [UNESP]
Vulcano, Luiz C. [UNESP]
Alves, Ana Liz G. [UNESP]
Watanabe, Marcos J. [UNESP]
Alonso, Juliana M. [UNESP]
Rollo, Hamilton A. [UNESP]
Hussni, Carlos A. [UNESP]
author_role author
author2 Barbosa, Roberta G. [UNESP]
Cerqueira, Nereide F. [UNESP]
Takahira, Regina K. [UNESP]
Vulcano, Luiz C. [UNESP]
Alves, Ana Liz G. [UNESP]
Watanabe, Marcos J. [UNESP]
Alonso, Juliana M. [UNESP]
Rollo, Hamilton A. [UNESP]
Hussni, Carlos A. [UNESP]
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Borghesan, Alexandre C. [UNESP]
Barbosa, Roberta G. [UNESP]
Cerqueira, Nereide F. [UNESP]
Takahira, Regina K. [UNESP]
Vulcano, Luiz C. [UNESP]
Alves, Ana Liz G. [UNESP]
Watanabe, Marcos J. [UNESP]
Alonso, Juliana M. [UNESP]
Rollo, Hamilton A. [UNESP]
Hussni, Carlos A. [UNESP]
dc.subject.por.fl_str_mv Activated partial thromboplastin time
Horses
Thrombosis
Ultrasound
Venography
topic Activated partial thromboplastin time
Horses
Thrombosis
Ultrasound
Venography
description Jugular thrombophlebitis is a major vascular disease in horses and can lead even to death. Heparin is used to inhibit thrombus growth in humans. The aim of this experiment was to evaluate heparin administration in horses with induced thrombophlebitis. Ten animals were subjected to experimental thrombophlebitis and divided into a control group and heparin group (HG). The HG received heparin (150 IU/kg) for 10 days. Coagulation tests, ultrasound, and venography were performed before and after thrombophlebitis induction. Comparing the HG and control group, a break in the growth of the thrombus after the start of administration of the drug and a decrease in the length of the thrombus with the appearance of flow down the sides of the cranial portion of the thrombus were observed. However, after discontinuation of heparin, fast daily growth of the thrombus and decreased blood flow to the side were observed.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:21:20Z
2018-12-11T17:21:20Z
2018-10-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.jevs.2018.06.010
Journal of Equine Veterinary Science, v. 69, p. 59-65.
0737-0806
http://hdl.handle.net/11449/176555
10.1016/j.jevs.2018.06.010
2-s2.0-85049508259
2-s2.0-85049508259.pdf
url http://dx.doi.org/10.1016/j.jevs.2018.06.010
http://hdl.handle.net/11449/176555
identifier_str_mv Journal of Equine Veterinary Science, v. 69, p. 59-65.
0737-0806
10.1016/j.jevs.2018.06.010
2-s2.0-85049508259
2-s2.0-85049508259.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Equine Veterinary Science
0,390
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 59-65
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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