Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1517-83822013000300026 http://hdl.handle.net/11449/112219 |
Resumo: | This study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair. |
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Repositório Institucional da UNESP |
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Evaluation of fecal microorganisms of children with cleft palate before and after palatoplastycleft palatecleft palate/surgeryenvironmental microbiologyfecessurgery/plasticThis study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair.Univ Sao Paulo, Hosp Rehabil Craniofacial Anomalies, Clin Anal Lab, Bauru, SP, BrazilUniv Estadual Sao Paulo Julio de Mesquita Filho, Escola Med, Dept Trop Dis, Botucatu, SP, BrazilUniv Estadual Sao Paulo Julio de Mesquita Filho, Escola Med, Dept Trop Dis, Botucatu, SP, BrazilSoc Brasileira MicrobiologiaUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Vieira, Narciso AlmeidaBorgo, Hilton CoimbraDalben, Gisele da SilvaBachega, Maria IreneMarques Pereira, Paulo Camara [UNESP]2014-12-03T13:10:31Z2014-12-03T13:10:31Z2013-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article835-838application/pdfhttp://dx.doi.org/10.1590/S1517-83822013000300026Brazilian Journal of Microbiology. São Paulo: Soc Brasileira Microbiologia, v. 44, n. 3, p. 835-838, 2013.1517-8382http://hdl.handle.net/11449/112219S1517-83822013000300026WOS:000332062100026S1517-83822013000300026.pdf1365320427418204Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Microbiology1.8100,630info:eu-repo/semantics/openAccess2024-08-15T15:23:02Zoai:repositorio.unesp.br:11449/112219Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-15T15:23:02Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
title |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
spellingShingle |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty Vieira, Narciso Almeida cleft palate cleft palate/surgery environmental microbiology feces surgery/plastic |
title_short |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
title_full |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
title_fullStr |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
title_full_unstemmed |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
title_sort |
Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty |
author |
Vieira, Narciso Almeida |
author_facet |
Vieira, Narciso Almeida Borgo, Hilton Coimbra Dalben, Gisele da Silva Bachega, Maria Irene Marques Pereira, Paulo Camara [UNESP] |
author_role |
author |
author2 |
Borgo, Hilton Coimbra Dalben, Gisele da Silva Bachega, Maria Irene Marques Pereira, Paulo Camara [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Vieira, Narciso Almeida Borgo, Hilton Coimbra Dalben, Gisele da Silva Bachega, Maria Irene Marques Pereira, Paulo Camara [UNESP] |
dc.subject.por.fl_str_mv |
cleft palate cleft palate/surgery environmental microbiology feces surgery/plastic |
topic |
cleft palate cleft palate/surgery environmental microbiology feces surgery/plastic |
description |
This study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-01 2014-12-03T13:10:31Z 2014-12-03T13:10:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1517-83822013000300026 Brazilian Journal of Microbiology. São Paulo: Soc Brasileira Microbiologia, v. 44, n. 3, p. 835-838, 2013. 1517-8382 http://hdl.handle.net/11449/112219 S1517-83822013000300026 WOS:000332062100026 S1517-83822013000300026.pdf 1365320427418204 |
url |
http://dx.doi.org/10.1590/S1517-83822013000300026 http://hdl.handle.net/11449/112219 |
identifier_str_mv |
Brazilian Journal of Microbiology. São Paulo: Soc Brasileira Microbiologia, v. 44, n. 3, p. 835-838, 2013. 1517-8382 S1517-83822013000300026 WOS:000332062100026 S1517-83822013000300026.pdf 1365320427418204 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Microbiology 1.810 0,630 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
835-838 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Brasileira Microbiologia |
publisher.none.fl_str_mv |
Soc Brasileira Microbiologia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128169770745856 |