Evaluation of the biocompatibility of root canal sealers using subcutaneous implants
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-77572007000300007 http://hdl.handle.net/11449/69650 |
Resumo: | The purpose of this study was to evaluate in vivo the biocompatibility of Endométhasone, Pulp Canal Sealer EWT and AHPlus root canal sealers after implantation in rat connective tissue. Twenty-four Wistar-Furth rats were used. Polyethylene tubes were filled with the sealers and implanted into specific dorsal subdermal tissue sites of the rats. Implants were removed after 3, 7 and 30 days, fixed and processed for glycol methacrylate-embedding technique to be examined microscopically. On the 3rd day, there was a mild inflammatory reaction to Pulp Canal Sealer EWT implants, but a severe response to the other sealers with presence of acute inflammatory cells. On the 7th day, tissue organization was more evident with attenuation of the inflammatory reaction, especially for the AH-Plus implants. On the 30th day, connective tissue with few inflammatory cells was observed in contact with all sealer implants. In this time interval, the tissue in contact with Pulp Canal Sealer EWT implants was more organized, while the tissue close to Endométhasone and AH-Plus implants showed a mild persistent inflammatory reaction and had similar results to each other. In conclusion, the sealers had a similar pattern of irritation, which was more severe in the beginning and milder with time, in such a way that all sealers showed a persistent mild reaction. Pulp Canal Sealer EWT yielded better tissue organization than Endométhasone and AH-Plus, which, in turn, showed similar results to each other. |
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Evaluation of the biocompatibility of root canal sealers using subcutaneous implantsBiocompatibilityEndodonticsGlycol methacrylateRoot canalSealerSubcutaneous implantThe purpose of this study was to evaluate in vivo the biocompatibility of Endométhasone, Pulp Canal Sealer EWT and AHPlus root canal sealers after implantation in rat connective tissue. Twenty-four Wistar-Furth rats were used. Polyethylene tubes were filled with the sealers and implanted into specific dorsal subdermal tissue sites of the rats. Implants were removed after 3, 7 and 30 days, fixed and processed for glycol methacrylate-embedding technique to be examined microscopically. On the 3rd day, there was a mild inflammatory reaction to Pulp Canal Sealer EWT implants, but a severe response to the other sealers with presence of acute inflammatory cells. On the 7th day, tissue organization was more evident with attenuation of the inflammatory reaction, especially for the AH-Plus implants. On the 30th day, connective tissue with few inflammatory cells was observed in contact with all sealer implants. In this time interval, the tissue in contact with Pulp Canal Sealer EWT implants was more organized, while the tissue close to Endométhasone and AH-Plus implants showed a mild persistent inflammatory reaction and had similar results to each other. In conclusion, the sealers had a similar pattern of irritation, which was more severe in the beginning and milder with time, in such a way that all sealers showed a persistent mild reaction. Pulp Canal Sealer EWT yielded better tissue organization than Endométhasone and AH-Plus, which, in turn, showed similar results to each other.Department of Endodontics Dental School of Araçatuba State University of São Paulo, Araçatuba, SPDepartment of Endodontics Dental School of of Piracicaba Campinas State University, Piracicaba, SPFaculdade de Odontologia de Araçatuba FOA-UNESP Endodontia, R. Jose Bonifacio, 1193, Araçatuba-SP, 16015-050Faculdade de Odontologia de Araçatuba FOA-UNESP Endodontia, R. Jose Bonifacio, 1193, Araçatuba-SP, 16015-050Universidade de São Paulo (USP)Universidade Estadual de Campinas (UNICAMP)Universidade Estadual Paulista (Unesp)Gomes-Filho, João E. [UNESP]Gomes, Brenda P. F. A.Zaia, Alexandre A.Ferraz, Caio R.Souza-Filho, Francisco J.2014-05-27T11:22:28Z2014-05-27T11:22:28Z2007-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article186-194application/pdfhttp://dx.doi.org/10.1590/S1678-77572007000300007Journal of Applied Oral Science, v. 15, n. 3, p. 186-194, 2007.1678-77571678-7765http://hdl.handle.net/11449/6965010.1590/S1678-77572007000300007S1678-77572007000300007WOS:0002567941000072-s2.0-345487272802-s2.0-34548727280.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-12-29T06:18:54Zoai:repositorio.unesp.br:11449/69650Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-29T06:18:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
title |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
spellingShingle |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants Gomes-Filho, João E. [UNESP] Biocompatibility Endodontics Glycol methacrylate Root canal Sealer Subcutaneous implant |
title_short |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
title_full |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
title_fullStr |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
title_full_unstemmed |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
title_sort |
Evaluation of the biocompatibility of root canal sealers using subcutaneous implants |
author |
Gomes-Filho, João E. [UNESP] |
author_facet |
Gomes-Filho, João E. [UNESP] Gomes, Brenda P. F. A. Zaia, Alexandre A. Ferraz, Caio R. Souza-Filho, Francisco J. |
author_role |
author |
author2 |
Gomes, Brenda P. F. A. Zaia, Alexandre A. Ferraz, Caio R. Souza-Filho, Francisco J. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual de Campinas (UNICAMP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Gomes-Filho, João E. [UNESP] Gomes, Brenda P. F. A. Zaia, Alexandre A. Ferraz, Caio R. Souza-Filho, Francisco J. |
dc.subject.por.fl_str_mv |
Biocompatibility Endodontics Glycol methacrylate Root canal Sealer Subcutaneous implant |
topic |
Biocompatibility Endodontics Glycol methacrylate Root canal Sealer Subcutaneous implant |
description |
The purpose of this study was to evaluate in vivo the biocompatibility of Endométhasone, Pulp Canal Sealer EWT and AHPlus root canal sealers after implantation in rat connective tissue. Twenty-four Wistar-Furth rats were used. Polyethylene tubes were filled with the sealers and implanted into specific dorsal subdermal tissue sites of the rats. Implants were removed after 3, 7 and 30 days, fixed and processed for glycol methacrylate-embedding technique to be examined microscopically. On the 3rd day, there was a mild inflammatory reaction to Pulp Canal Sealer EWT implants, but a severe response to the other sealers with presence of acute inflammatory cells. On the 7th day, tissue organization was more evident with attenuation of the inflammatory reaction, especially for the AH-Plus implants. On the 30th day, connective tissue with few inflammatory cells was observed in contact with all sealer implants. In this time interval, the tissue in contact with Pulp Canal Sealer EWT implants was more organized, while the tissue close to Endométhasone and AH-Plus implants showed a mild persistent inflammatory reaction and had similar results to each other. In conclusion, the sealers had a similar pattern of irritation, which was more severe in the beginning and milder with time, in such a way that all sealers showed a persistent mild reaction. Pulp Canal Sealer EWT yielded better tissue organization than Endométhasone and AH-Plus, which, in turn, showed similar results to each other. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-05-01 2014-05-27T11:22:28Z 2014-05-27T11:22:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-77572007000300007 Journal of Applied Oral Science, v. 15, n. 3, p. 186-194, 2007. 1678-7757 1678-7765 http://hdl.handle.net/11449/69650 10.1590/S1678-77572007000300007 S1678-77572007000300007 WOS:000256794100007 2-s2.0-34548727280 2-s2.0-34548727280.pdf |
url |
http://dx.doi.org/10.1590/S1678-77572007000300007 http://hdl.handle.net/11449/69650 |
identifier_str_mv |
Journal of Applied Oral Science, v. 15, n. 3, p. 186-194, 2007. 1678-7757 1678-7765 10.1590/S1678-77572007000300007 S1678-77572007000300007 WOS:000256794100007 2-s2.0-34548727280 2-s2.0-34548727280.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science 1.709 0,645 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
186-194 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965446209798144 |