Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.clnu.2016.03.020 http://hdl.handle.net/11449/168596 |
Resumo: | Background & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality. |
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Repositório Institucional da UNESP |
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Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patientsDialysisHandgrip strengthMortalityNutritional assessmentBackground & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Faculdade de Medicina de Botucatu UNESP Univ Estadual Paulista Department of Clinical MedicineFaculdade de Medicina de Botucatu UNESP Univ Estadual Paulista Department of Clinical MedicineUniversidade Estadual Paulista (Unesp)Vogt, Barbara Perez [UNESP]Borges, Mariana Clementoni Costa [UNESP]Goés, Cassiana Regina de [UNESP]Caramori, Jacqueline Costa Teixeira [UNESP]2018-12-11T16:42:05Z2018-12-11T16:42:05Z2016-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1429-1433application/pdfhttp://dx.doi.org/10.1016/j.clnu.2016.03.020Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016.1532-19830261-5614http://hdl.handle.net/11449/16859610.1016/j.clnu.2016.03.0202-s2.0-849643373752-s2.0-84964337375.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Nutrition1,905info:eu-repo/semantics/openAccess2023-11-02T06:07:55Zoai:repositorio.unesp.br:11449/168596Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:42:42.260819Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
title |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
spellingShingle |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients Vogt, Barbara Perez [UNESP] Dialysis Handgrip strength Mortality Nutritional assessment |
title_short |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
title_full |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
title_fullStr |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
title_full_unstemmed |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
title_sort |
Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients |
author |
Vogt, Barbara Perez [UNESP] |
author_facet |
Vogt, Barbara Perez [UNESP] Borges, Mariana Clementoni Costa [UNESP] Goés, Cassiana Regina de [UNESP] Caramori, Jacqueline Costa Teixeira [UNESP] |
author_role |
author |
author2 |
Borges, Mariana Clementoni Costa [UNESP] Goés, Cassiana Regina de [UNESP] Caramori, Jacqueline Costa Teixeira [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Vogt, Barbara Perez [UNESP] Borges, Mariana Clementoni Costa [UNESP] Goés, Cassiana Regina de [UNESP] Caramori, Jacqueline Costa Teixeira [UNESP] |
dc.subject.por.fl_str_mv |
Dialysis Handgrip strength Mortality Nutritional assessment |
topic |
Dialysis Handgrip strength Mortality Nutritional assessment |
description |
Background & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-12-01 2018-12-11T16:42:05Z 2018-12-11T16:42:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.clnu.2016.03.020 Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016. 1532-1983 0261-5614 http://hdl.handle.net/11449/168596 10.1016/j.clnu.2016.03.020 2-s2.0-84964337375 2-s2.0-84964337375.pdf |
url |
http://dx.doi.org/10.1016/j.clnu.2016.03.020 http://hdl.handle.net/11449/168596 |
identifier_str_mv |
Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016. 1532-1983 0261-5614 10.1016/j.clnu.2016.03.020 2-s2.0-84964337375 2-s2.0-84964337375.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Nutrition 1,905 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1429-1433 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128689902190592 |