Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients

Detalhes bibliográficos
Autor(a) principal: Vogt, Barbara Perez [UNESP]
Data de Publicação: 2016
Outros Autores: Borges, Mariana Clementoni Costa [UNESP], Goés, Cassiana Regina de [UNESP], Caramori, Jacqueline Costa Teixeira [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.clnu.2016.03.020
http://hdl.handle.net/11449/168596
Resumo: Background & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality.
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spelling Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patientsDialysisHandgrip strengthMortalityNutritional assessmentBackground & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Faculdade de Medicina de Botucatu UNESP Univ Estadual Paulista Department of Clinical MedicineFaculdade de Medicina de Botucatu UNESP Univ Estadual Paulista Department of Clinical MedicineUniversidade Estadual Paulista (Unesp)Vogt, Barbara Perez [UNESP]Borges, Mariana Clementoni Costa [UNESP]Goés, Cassiana Regina de [UNESP]Caramori, Jacqueline Costa Teixeira [UNESP]2018-12-11T16:42:05Z2018-12-11T16:42:05Z2016-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1429-1433application/pdfhttp://dx.doi.org/10.1016/j.clnu.2016.03.020Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016.1532-19830261-5614http://hdl.handle.net/11449/16859610.1016/j.clnu.2016.03.0202-s2.0-849643373752-s2.0-84964337375.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Nutrition1,905info:eu-repo/semantics/openAccess2023-11-02T06:07:55Zoai:repositorio.unesp.br:11449/168596Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:42:42.260819Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
title Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
spellingShingle Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
Vogt, Barbara Perez [UNESP]
Dialysis
Handgrip strength
Mortality
Nutritional assessment
title_short Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
title_full Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
title_fullStr Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
title_full_unstemmed Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
title_sort Handgrip strength is an independent predictor of all-cause mortality in maintenance dialysis patients
author Vogt, Barbara Perez [UNESP]
author_facet Vogt, Barbara Perez [UNESP]
Borges, Mariana Clementoni Costa [UNESP]
Goés, Cassiana Regina de [UNESP]
Caramori, Jacqueline Costa Teixeira [UNESP]
author_role author
author2 Borges, Mariana Clementoni Costa [UNESP]
Goés, Cassiana Regina de [UNESP]
Caramori, Jacqueline Costa Teixeira [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Vogt, Barbara Perez [UNESP]
Borges, Mariana Clementoni Costa [UNESP]
Goés, Cassiana Regina de [UNESP]
Caramori, Jacqueline Costa Teixeira [UNESP]
dc.subject.por.fl_str_mv Dialysis
Handgrip strength
Mortality
Nutritional assessment
topic Dialysis
Handgrip strength
Mortality
Nutritional assessment
description Background & aims Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). Methods This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014. Patients were followed-up until June 2015. Results Two-hundred sixty five patients were enrolled (218 HD and 47 PD) and they were followed for 13.4 ± 7.9 months. During the follow-up period, 53 patients (20%) have died, 36 patients (13.6%) have undergone renal transplantation, 13 patients (4.9%) have switched off dialysis method and 5 patients (1.9%) have transferred to another facility. The cut-off of HGS able to predict mortality was 22.5 kg for men and 7 kg for women. Using this cut-off to fit the Kaplan–Meier survival curve, the association of HGS with all-cause mortality for both genders was confirmed. Finally, in the multivariate analysis adjusted for demographic, clinical and nutritional variables, HGS remained significant predictor of mortality, independent of dialysis modality. Conclusions HGS cut-offs that predict mortality were 22.5 kg for men and 7 kg for women. HGS was associated with mortality independent of dialysis modality.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
2018-12-11T16:42:05Z
2018-12-11T16:42:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.clnu.2016.03.020
Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016.
1532-1983
0261-5614
http://hdl.handle.net/11449/168596
10.1016/j.clnu.2016.03.020
2-s2.0-84964337375
2-s2.0-84964337375.pdf
url http://dx.doi.org/10.1016/j.clnu.2016.03.020
http://hdl.handle.net/11449/168596
identifier_str_mv Clinical Nutrition, v. 35, n. 6, p. 1429-1433, 2016.
1532-1983
0261-5614
10.1016/j.clnu.2016.03.020
2-s2.0-84964337375
2-s2.0-84964337375.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clinical Nutrition
1,905
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1429-1433
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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