Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)

Detalhes bibliográficos
Autor(a) principal: Regasini, Luis Octávio [UNESP]
Data de Publicação: 2008
Outros Autores: De Oliveira, Camila Martins [UNESP], Vellosa, José Carlos Rebuglio [UNESP], Oliveira, Olga Maria Mascarenhas De Faria [UNESP], Silva, Dulce Helena Siqueira [UNESP], Bolzani, Vanderlan Da Silva [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/225390
Resumo: As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals.
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spelling Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)ABTSAntioxidantCaesalpinioideaeDPPHFabaceaeFlavonoidFlavonolFree radical scavenging activityLeguminosaePterogyne nitensAs part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals.Department of Organic Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Biochemistry and Technological Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Organic Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Biochemistry and Technological Chemistry Institute of Chemistry São Paulo State University, AraraquaraUniversidade Estadual Paulista (UNESP)Regasini, Luis Octávio [UNESP]De Oliveira, Camila Martins [UNESP]Vellosa, José Carlos Rebuglio [UNESP]Oliveira, Olga Maria Mascarenhas De Faria [UNESP]Silva, Dulce Helena Siqueira [UNESP]Bolzani, Vanderlan Da Silva [UNESP]2022-04-28T20:48:14Z2022-04-28T20:48:14Z2008-12-17info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4609-4613African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008.1684-5315http://hdl.handle.net/11449/2253902-s2.0-58149242568Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAfrican Journal of Biotechnologyinfo:eu-repo/semantics/openAccess2022-04-28T20:48:14Zoai:repositorio.unesp.br:11449/225390Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:16:35.986739Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
title Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
spellingShingle Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
Regasini, Luis Octávio [UNESP]
ABTS
Antioxidant
Caesalpinioideae
DPPH
Fabaceae
Flavonoid
Flavonol
Free radical scavenging activity
Leguminosae
Pterogyne nitens
title_short Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
title_full Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
title_fullStr Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
title_full_unstemmed Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
title_sort Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
author Regasini, Luis Octávio [UNESP]
author_facet Regasini, Luis Octávio [UNESP]
De Oliveira, Camila Martins [UNESP]
Vellosa, José Carlos Rebuglio [UNESP]
Oliveira, Olga Maria Mascarenhas De Faria [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Bolzani, Vanderlan Da Silva [UNESP]
author_role author
author2 De Oliveira, Camila Martins [UNESP]
Vellosa, José Carlos Rebuglio [UNESP]
Oliveira, Olga Maria Mascarenhas De Faria [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Bolzani, Vanderlan Da Silva [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Regasini, Luis Octávio [UNESP]
De Oliveira, Camila Martins [UNESP]
Vellosa, José Carlos Rebuglio [UNESP]
Oliveira, Olga Maria Mascarenhas De Faria [UNESP]
Silva, Dulce Helena Siqueira [UNESP]
Bolzani, Vanderlan Da Silva [UNESP]
dc.subject.por.fl_str_mv ABTS
Antioxidant
Caesalpinioideae
DPPH
Fabaceae
Flavonoid
Flavonol
Free radical scavenging activity
Leguminosae
Pterogyne nitens
topic ABTS
Antioxidant
Caesalpinioideae
DPPH
Fabaceae
Flavonoid
Flavonol
Free radical scavenging activity
Leguminosae
Pterogyne nitens
description As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-17
2022-04-28T20:48:14Z
2022-04-28T20:48:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008.
1684-5315
http://hdl.handle.net/11449/225390
2-s2.0-58149242568
identifier_str_mv African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008.
1684-5315
2-s2.0-58149242568
url http://hdl.handle.net/11449/225390
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv African Journal of Biotechnology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 4609-4613
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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