Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/225390 |
Resumo: | As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals. |
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Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)ABTSAntioxidantCaesalpinioideaeDPPHFabaceaeFlavonoidFlavonolFree radical scavenging activityLeguminosaePterogyne nitensAs part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals.Department of Organic Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Biochemistry and Technological Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Organic Chemistry Institute of Chemistry São Paulo State University, AraraquaraDepartment of Biochemistry and Technological Chemistry Institute of Chemistry São Paulo State University, AraraquaraUniversidade Estadual Paulista (UNESP)Regasini, Luis Octávio [UNESP]De Oliveira, Camila Martins [UNESP]Vellosa, José Carlos Rebuglio [UNESP]Oliveira, Olga Maria Mascarenhas De Faria [UNESP]Silva, Dulce Helena Siqueira [UNESP]Bolzani, Vanderlan Da Silva [UNESP]2022-04-28T20:48:14Z2022-04-28T20:48:14Z2008-12-17info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4609-4613African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008.1684-5315http://hdl.handle.net/11449/2253902-s2.0-58149242568Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAfrican Journal of Biotechnologyinfo:eu-repo/semantics/openAccess2022-04-28T20:48:14Zoai:repositorio.unesp.br:11449/225390Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:16:35.986739Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
title |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
spellingShingle |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) Regasini, Luis Octávio [UNESP] ABTS Antioxidant Caesalpinioideae DPPH Fabaceae Flavonoid Flavonol Free radical scavenging activity Leguminosae Pterogyne nitens |
title_short |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
title_full |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
title_fullStr |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
title_full_unstemmed |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
title_sort |
Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae) |
author |
Regasini, Luis Octávio [UNESP] |
author_facet |
Regasini, Luis Octávio [UNESP] De Oliveira, Camila Martins [UNESP] Vellosa, José Carlos Rebuglio [UNESP] Oliveira, Olga Maria Mascarenhas De Faria [UNESP] Silva, Dulce Helena Siqueira [UNESP] Bolzani, Vanderlan Da Silva [UNESP] |
author_role |
author |
author2 |
De Oliveira, Camila Martins [UNESP] Vellosa, José Carlos Rebuglio [UNESP] Oliveira, Olga Maria Mascarenhas De Faria [UNESP] Silva, Dulce Helena Siqueira [UNESP] Bolzani, Vanderlan Da Silva [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Regasini, Luis Octávio [UNESP] De Oliveira, Camila Martins [UNESP] Vellosa, José Carlos Rebuglio [UNESP] Oliveira, Olga Maria Mascarenhas De Faria [UNESP] Silva, Dulce Helena Siqueira [UNESP] Bolzani, Vanderlan Da Silva [UNESP] |
dc.subject.por.fl_str_mv |
ABTS Antioxidant Caesalpinioideae DPPH Fabaceae Flavonoid Flavonol Free radical scavenging activity Leguminosae Pterogyne nitens |
topic |
ABTS Antioxidant Caesalpinioideae DPPH Fabaceae Flavonoid Flavonol Free radical scavenging activity Leguminosae Pterogyne nitens |
description |
As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-17 2022-04-28T20:48:14Z 2022-04-28T20:48:14Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008. 1684-5315 http://hdl.handle.net/11449/225390 2-s2.0-58149242568 |
identifier_str_mv |
African Journal of Biotechnology, v. 7, n. 24, p. 4609-4613, 2008. 1684-5315 2-s2.0-58149242568 |
url |
http://hdl.handle.net/11449/225390 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
African Journal of Biotechnology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
4609-4613 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129303955636224 |