LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM
Autor(a) principal: | |
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Data de Publicação: | 1994 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.gmb.org.br/Revistas/V17/v17a33.pdf http://hdl.handle.net/11449/34507 |
Resumo: | Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system. |
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LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEMThirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.UNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,INST BIOCIENCIAS,DEPT GENET,BR-18618000 BOTUCATU,SP,BRAZILUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,INST BIOCIENCIAS,DEPT GENET,BR-18618000 BOTUCATU,SP,BRAZILSoc Brasil GeneticaUniversidade Estadual Paulista (Unesp)Rogatto, Silvia Regina [UNESP]Rainho, C. A.Neto, J. B.Casartelli, C.2014-05-20T15:23:48Z2014-05-20T15:23:48Z1994-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article215-222application/pdfhttp://www.gmb.org.br/Revistas/V17/v17a33.pdfRevista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 17, n. 2, p. 215-222, 1994.0100-8455http://hdl.handle.net/11449/34507WOS:A1994PA12300013WOSA1994PA12300013.pdf88148235451595040000-0002-0285-1162Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Brasileira de Genéticainfo:eu-repo/semantics/openAccess2023-10-24T06:09:41Zoai:repositorio.unesp.br:11449/34507Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:49:47.662450Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
title |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
spellingShingle |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM Rogatto, Silvia Regina [UNESP] |
title_short |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
title_full |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
title_fullStr |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
title_full_unstemmed |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
title_sort |
LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM |
author |
Rogatto, Silvia Regina [UNESP] |
author_facet |
Rogatto, Silvia Regina [UNESP] Rainho, C. A. Neto, J. B. Casartelli, C. |
author_role |
author |
author2 |
Rainho, C. A. Neto, J. B. Casartelli, C. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Rogatto, Silvia Regina [UNESP] Rainho, C. A. Neto, J. B. Casartelli, C. |
description |
Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-06-01 2014-05-20T15:23:48Z 2014-05-20T15:23:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.gmb.org.br/Revistas/V17/v17a33.pdf Revista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 17, n. 2, p. 215-222, 1994. 0100-8455 http://hdl.handle.net/11449/34507 WOS:A1994PA12300013 WOSA1994PA12300013.pdf 8814823545159504 0000-0002-0285-1162 |
url |
http://www.gmb.org.br/Revistas/V17/v17a33.pdf http://hdl.handle.net/11449/34507 |
identifier_str_mv |
Revista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 17, n. 2, p. 215-222, 1994. 0100-8455 WOS:A1994PA12300013 WOSA1994PA12300013.pdf 8814823545159504 0000-0002-0285-1162 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Revista Brasileira de Genética |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
215-222 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Brasil Genetica |
publisher.none.fl_str_mv |
Soc Brasil Genetica |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128569712312320 |