Loss of the sex chromosome in human neoplasias of the nervous system

Detalhes bibliográficos
Autor(a) principal: Rogatto, S. R. [UNESP]
Data de Publicação: 1994
Outros Autores: Rainho, C. A. [UNESP], Neto, J. B. [UNESP], Casartelli, C. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/223974
Resumo: Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.
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spelling Loss of the sex chromosome in human neoplasias of the nervous systemThirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.Departamento de Genetica Instituto de Biociencias Universidade Estadual Paulista, 18618-000 Botucatu, SPDepartamento de Genetica Instituto de Biociencias Universidade Estadual Paulista, 18618-000 Botucatu, SPUniversidade Estadual Paulista (UNESP)Rogatto, S. R. [UNESP]Rainho, C. A. [UNESP]Neto, J. B. [UNESP]Casartelli, C. [UNESP]2022-04-28T19:54:00Z2022-04-28T19:54:00Z1994-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article215-222Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994.0100-8455http://hdl.handle.net/11449/2239742-s2.0-0027993880Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Geneticsinfo:eu-repo/semantics/openAccess2022-04-28T19:54:00Zoai:repositorio.unesp.br:11449/223974Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Loss of the sex chromosome in human neoplasias of the nervous system
title Loss of the sex chromosome in human neoplasias of the nervous system
spellingShingle Loss of the sex chromosome in human neoplasias of the nervous system
Rogatto, S. R. [UNESP]
title_short Loss of the sex chromosome in human neoplasias of the nervous system
title_full Loss of the sex chromosome in human neoplasias of the nervous system
title_fullStr Loss of the sex chromosome in human neoplasias of the nervous system
title_full_unstemmed Loss of the sex chromosome in human neoplasias of the nervous system
title_sort Loss of the sex chromosome in human neoplasias of the nervous system
author Rogatto, S. R. [UNESP]
author_facet Rogatto, S. R. [UNESP]
Rainho, C. A. [UNESP]
Neto, J. B. [UNESP]
Casartelli, C. [UNESP]
author_role author
author2 Rainho, C. A. [UNESP]
Neto, J. B. [UNESP]
Casartelli, C. [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Rogatto, S. R. [UNESP]
Rainho, C. A. [UNESP]
Neto, J. B. [UNESP]
Casartelli, C. [UNESP]
description Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.
publishDate 1994
dc.date.none.fl_str_mv 1994-01-01
2022-04-28T19:54:00Z
2022-04-28T19:54:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994.
0100-8455
http://hdl.handle.net/11449/223974
2-s2.0-0027993880
identifier_str_mv Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994.
0100-8455
2-s2.0-0027993880
url http://hdl.handle.net/11449/223974
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Genetics
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 215-222
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1803047419625078784

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