Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging

Detalhes bibliográficos
Autor(a) principal: Cefali, Letícia Caramori [UNESP]
Data de Publicação: 2015
Outros Autores: Souza-Moreira, Tatiana Maria [UNESP], Corrêa, Marcos Antônio [UNESP], Salgado, Hérida Regina Nunes [UNESP], Isaac, Vera Lucia Borges [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1984-82502015000300010
http://hdl.handle.net/11449/177623
Resumo: Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging.
id UNSP_f05991ec0e0707abb5833e7191e0fb8e
oai_identifier_str oai:repositorio.unesp.br:11449/177623
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Development and evaluation of an emulsion containing lycopene for combating acceleration of skin agingCarotenoid/antioxidant activityLycopene/emulsion form/cytotoxicityLycopene/emulsion form/rheologyLycopene/emulsion form/thermal analysesLycopene/emulsion orm/permeationPhytocosmeticsSkin aging/treatmentLycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging.Cosmetology Laboratory LacCos Department of Drugs and Medicines University of Sao Paulo State UNESPCosmetology Laboratory LacCos Department of Drugs and Medicines University of Sao Paulo State UNESPUniversidade Estadual Paulista (Unesp)Cefali, Letícia Caramori [UNESP]Souza-Moreira, Tatiana Maria [UNESP]Corrêa, Marcos Antônio [UNESP]Salgado, Hérida Regina Nunes [UNESP]Isaac, Vera Lucia Borges [UNESP]2018-12-11T17:26:22Z2018-12-11T17:26:22Z2015-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article579-590application/pdfhttp://dx.doi.org/10.1590/S1984-82502015000300010Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015.2175-97901984-8250http://hdl.handle.net/11449/17762310.1590/S1984-82502015000300010S1984-825020150003005792-s2.0-84948776814S1984-82502015000300579.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Pharmaceutical Sciences0,2140,214info:eu-repo/semantics/openAccess2024-06-24T13:45:01Zoai:repositorio.unesp.br:11449/177623Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:25:25.711524Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
title Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
spellingShingle Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
Cefali, Letícia Caramori [UNESP]
Carotenoid/antioxidant activity
Lycopene/emulsion form/cytotoxicity
Lycopene/emulsion form/rheology
Lycopene/emulsion form/thermal analyses
Lycopene/emulsion orm/permeation
Phytocosmetics
Skin aging/treatment
title_short Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
title_full Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
title_fullStr Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
title_full_unstemmed Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
title_sort Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
author Cefali, Letícia Caramori [UNESP]
author_facet Cefali, Letícia Caramori [UNESP]
Souza-Moreira, Tatiana Maria [UNESP]
Corrêa, Marcos Antônio [UNESP]
Salgado, Hérida Regina Nunes [UNESP]
Isaac, Vera Lucia Borges [UNESP]
author_role author
author2 Souza-Moreira, Tatiana Maria [UNESP]
Corrêa, Marcos Antônio [UNESP]
Salgado, Hérida Regina Nunes [UNESP]
Isaac, Vera Lucia Borges [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Cefali, Letícia Caramori [UNESP]
Souza-Moreira, Tatiana Maria [UNESP]
Corrêa, Marcos Antônio [UNESP]
Salgado, Hérida Regina Nunes [UNESP]
Isaac, Vera Lucia Borges [UNESP]
dc.subject.por.fl_str_mv Carotenoid/antioxidant activity
Lycopene/emulsion form/cytotoxicity
Lycopene/emulsion form/rheology
Lycopene/emulsion form/thermal analyses
Lycopene/emulsion orm/permeation
Phytocosmetics
Skin aging/treatment
topic Carotenoid/antioxidant activity
Lycopene/emulsion form/cytotoxicity
Lycopene/emulsion form/rheology
Lycopene/emulsion form/thermal analyses
Lycopene/emulsion orm/permeation
Phytocosmetics
Skin aging/treatment
description Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-01
2018-12-11T17:26:22Z
2018-12-11T17:26:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1984-82502015000300010
Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015.
2175-9790
1984-8250
http://hdl.handle.net/11449/177623
10.1590/S1984-82502015000300010
S1984-82502015000300579
2-s2.0-84948776814
S1984-82502015000300579.pdf
url http://dx.doi.org/10.1590/S1984-82502015000300010
http://hdl.handle.net/11449/177623
identifier_str_mv Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015.
2175-9790
1984-8250
10.1590/S1984-82502015000300010
S1984-82502015000300579
2-s2.0-84948776814
S1984-82502015000300579.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Pharmaceutical Sciences
0,214
0,214
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 579-590
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128359144620032