Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1984-82502015000300010 http://hdl.handle.net/11449/177623 |
Resumo: | Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging. |
id |
UNSP_f05991ec0e0707abb5833e7191e0fb8e |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/177623 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin agingCarotenoid/antioxidant activityLycopene/emulsion form/cytotoxicityLycopene/emulsion form/rheologyLycopene/emulsion form/thermal analysesLycopene/emulsion orm/permeationPhytocosmeticsSkin aging/treatmentLycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging.Cosmetology Laboratory LacCos Department of Drugs and Medicines University of Sao Paulo State UNESPCosmetology Laboratory LacCos Department of Drugs and Medicines University of Sao Paulo State UNESPUniversidade Estadual Paulista (Unesp)Cefali, Letícia Caramori [UNESP]Souza-Moreira, Tatiana Maria [UNESP]Corrêa, Marcos Antônio [UNESP]Salgado, Hérida Regina Nunes [UNESP]Isaac, Vera Lucia Borges [UNESP]2018-12-11T17:26:22Z2018-12-11T17:26:22Z2015-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article579-590application/pdfhttp://dx.doi.org/10.1590/S1984-82502015000300010Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015.2175-97901984-8250http://hdl.handle.net/11449/17762310.1590/S1984-82502015000300010S1984-825020150003005792-s2.0-84948776814S1984-82502015000300579.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Pharmaceutical Sciences0,2140,214info:eu-repo/semantics/openAccess2024-06-24T13:45:01Zoai:repositorio.unesp.br:11449/177623Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:25:25.711524Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
title |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
spellingShingle |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging Cefali, Letícia Caramori [UNESP] Carotenoid/antioxidant activity Lycopene/emulsion form/cytotoxicity Lycopene/emulsion form/rheology Lycopene/emulsion form/thermal analyses Lycopene/emulsion orm/permeation Phytocosmetics Skin aging/treatment |
title_short |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
title_full |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
title_fullStr |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
title_full_unstemmed |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
title_sort |
Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging |
author |
Cefali, Letícia Caramori [UNESP] |
author_facet |
Cefali, Letícia Caramori [UNESP] Souza-Moreira, Tatiana Maria [UNESP] Corrêa, Marcos Antônio [UNESP] Salgado, Hérida Regina Nunes [UNESP] Isaac, Vera Lucia Borges [UNESP] |
author_role |
author |
author2 |
Souza-Moreira, Tatiana Maria [UNESP] Corrêa, Marcos Antônio [UNESP] Salgado, Hérida Regina Nunes [UNESP] Isaac, Vera Lucia Borges [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Cefali, Letícia Caramori [UNESP] Souza-Moreira, Tatiana Maria [UNESP] Corrêa, Marcos Antônio [UNESP] Salgado, Hérida Regina Nunes [UNESP] Isaac, Vera Lucia Borges [UNESP] |
dc.subject.por.fl_str_mv |
Carotenoid/antioxidant activity Lycopene/emulsion form/cytotoxicity Lycopene/emulsion form/rheology Lycopene/emulsion form/thermal analyses Lycopene/emulsion orm/permeation Phytocosmetics Skin aging/treatment |
topic |
Carotenoid/antioxidant activity Lycopene/emulsion form/cytotoxicity Lycopene/emulsion form/rheology Lycopene/emulsion form/thermal analyses Lycopene/emulsion orm/permeation Phytocosmetics Skin aging/treatment |
description |
Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-07-01 2018-12-11T17:26:22Z 2018-12-11T17:26:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1984-82502015000300010 Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015. 2175-9790 1984-8250 http://hdl.handle.net/11449/177623 10.1590/S1984-82502015000300010 S1984-82502015000300579 2-s2.0-84948776814 S1984-82502015000300579.pdf |
url |
http://dx.doi.org/10.1590/S1984-82502015000300010 http://hdl.handle.net/11449/177623 |
identifier_str_mv |
Brazilian Journal of Pharmaceutical Sciences, v. 51, n. 3, p. 579-590, 2015. 2175-9790 1984-8250 10.1590/S1984-82502015000300010 S1984-82502015000300579 2-s2.0-84948776814 S1984-82502015000300579.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences 0,214 0,214 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
579-590 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128359144620032 |