Escherichia albertii Pathogenesis
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1128/ecosalplus.ESP-0015-2019 http://hdl.handle.net/11449/201140 |
Resumo: | Escherichia albertii is an emerging enteropathogen of humans and many avian species. This bacterium is a close relative of Escherichia coli and has been frequently misidentified as enteropathogenic or enterohemorrhagic E. coli due to their similarity in phenotypic and genetic features, such as various biochemical properties and the possession of a type III secretion system encoded by the locus of enterocyte effacement. This pathogen causes outbreaks of gastroenteritis, and some strains produce Shiga toxin. Although many genetic and phenotypic studies have been published and the genome sequences of more than 200 E. albertii strains are now available, the clinical significance of this species is not yet fully understood. The apparent zoonotic nature of the disease requires a deeper understanding of the transmission routes and mechanisms of E. albertii to develop effective measures to control its transmission and infection. Here, we review the current knowledge of the phylogenic relationship of E. albertii with other Escherichia species and the biochemical and genetic properties of E. albertii, with particular emphasis on the repertoire of virulence factors and the mechanisms of pathogenicity, and we hope this provides a basis for future studies of this important emerging enteropathogen. |
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Escherichia albertii PathogenesisEscherichia albertii is an emerging enteropathogen of humans and many avian species. This bacterium is a close relative of Escherichia coli and has been frequently misidentified as enteropathogenic or enterohemorrhagic E. coli due to their similarity in phenotypic and genetic features, such as various biochemical properties and the possession of a type III secretion system encoded by the locus of enterocyte effacement. This pathogen causes outbreaks of gastroenteritis, and some strains produce Shiga toxin. Although many genetic and phenotypic studies have been published and the genome sequences of more than 200 E. albertii strains are now available, the clinical significance of this species is not yet fully understood. The apparent zoonotic nature of the disease requires a deeper understanding of the transmission routes and mechanisms of E. albertii to develop effective measures to control its transmission and infection. Here, we review the current knowledge of the phylogenic relationship of E. albertii with other Escherichia species and the biochemical and genetic properties of E. albertii, with particular emphasis on the repertoire of virulence factors and the mechanisms of pathogenicity, and we hope this provides a basis for future studies of this important emerging enteropathogen.Departamento de Microbiologia Imunologia e Parasitologia Escola Paulista de Medicina Universidade Federal de São PauloDepartment of Microbiology Graduate School of Medical and Dental Sciences Kagoshima UniversityUniversidade Estadual Paulista (UNESP) Instituto de Biociências Campus de BotucatuUniversidade Santo AmaroDepartment of Bacteriology Faculty of Medical Sciences Kyushu UniversityUniversidade Estadual Paulista (UNESP) Instituto de Biociências Campus de BotucatuUniversidade Federal de São Paulo (UNIFESP)Kagoshima UniversityUniversidade Estadual Paulista (Unesp)Universidade Santo AmaroKyushu UniversityGomes, Tânia A TOoka, TadasukeHernandes, Rodrigo T. [UNESP]Yamamoto, DeniseHayashi, Tetsuya2020-12-12T02:25:06Z2020-12-12T02:25:06Z2020-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1128/ecosalplus.ESP-0015-2019EcoSal Plus, v. 9, n. 1, 2020.2324-6200http://hdl.handle.net/11449/20114010.1128/ecosalplus.ESP-0015-20192-s2.0-85087139831Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengEcoSal Plusinfo:eu-repo/semantics/openAccess2021-10-23T16:08:44Zoai:repositorio.unesp.br:11449/201140Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T16:08:44Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Escherichia albertii Pathogenesis |
title |
Escherichia albertii Pathogenesis |
spellingShingle |
Escherichia albertii Pathogenesis Gomes, Tânia A T |
title_short |
Escherichia albertii Pathogenesis |
title_full |
Escherichia albertii Pathogenesis |
title_fullStr |
Escherichia albertii Pathogenesis |
title_full_unstemmed |
Escherichia albertii Pathogenesis |
title_sort |
Escherichia albertii Pathogenesis |
author |
Gomes, Tânia A T |
author_facet |
Gomes, Tânia A T Ooka, Tadasuke Hernandes, Rodrigo T. [UNESP] Yamamoto, Denise Hayashi, Tetsuya |
author_role |
author |
author2 |
Ooka, Tadasuke Hernandes, Rodrigo T. [UNESP] Yamamoto, Denise Hayashi, Tetsuya |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Kagoshima University Universidade Estadual Paulista (Unesp) Universidade Santo Amaro Kyushu University |
dc.contributor.author.fl_str_mv |
Gomes, Tânia A T Ooka, Tadasuke Hernandes, Rodrigo T. [UNESP] Yamamoto, Denise Hayashi, Tetsuya |
description |
Escherichia albertii is an emerging enteropathogen of humans and many avian species. This bacterium is a close relative of Escherichia coli and has been frequently misidentified as enteropathogenic or enterohemorrhagic E. coli due to their similarity in phenotypic and genetic features, such as various biochemical properties and the possession of a type III secretion system encoded by the locus of enterocyte effacement. This pathogen causes outbreaks of gastroenteritis, and some strains produce Shiga toxin. Although many genetic and phenotypic studies have been published and the genome sequences of more than 200 E. albertii strains are now available, the clinical significance of this species is not yet fully understood. The apparent zoonotic nature of the disease requires a deeper understanding of the transmission routes and mechanisms of E. albertii to develop effective measures to control its transmission and infection. Here, we review the current knowledge of the phylogenic relationship of E. albertii with other Escherichia species and the biochemical and genetic properties of E. albertii, with particular emphasis on the repertoire of virulence factors and the mechanisms of pathogenicity, and we hope this provides a basis for future studies of this important emerging enteropathogen. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:25:06Z 2020-12-12T02:25:06Z 2020-06-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1128/ecosalplus.ESP-0015-2019 EcoSal Plus, v. 9, n. 1, 2020. 2324-6200 http://hdl.handle.net/11449/201140 10.1128/ecosalplus.ESP-0015-2019 2-s2.0-85087139831 |
url |
http://dx.doi.org/10.1128/ecosalplus.ESP-0015-2019 http://hdl.handle.net/11449/201140 |
identifier_str_mv |
EcoSal Plus, v. 9, n. 1, 2020. 2324-6200 10.1128/ecosalplus.ESP-0015-2019 2-s2.0-85087139831 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
EcoSal Plus |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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1799964577248575488 |