The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.4067/S0717-95022020000601525 http://hdl.handle.net/11449/206775 |
Resumo: | SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose. |
| id |
UNSP_f5fe94e66fa514ea775c86d28dc6e5a0 |
|---|---|
| oai_identifier_str |
oai:repositorio.unesp.br:11449/206775 |
| network_acronym_str |
UNSP |
| network_name_str |
Repositório Institucional da UNESP |
| repository_id_str |
2946 |
| spelling |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitorLa morfología del testículo de paca (Cuniculus paca) con altas dosis de letrozol, un inhibidor de la aromatasaGonadalSpermatogenesisToxicSUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.Department of Surgery School of Veterinary Medicine and Animal Science University of São Paulo (FMVZ-USP), Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade UniversitáriaFaculdade Ingá Uningá - Departamento de Medicina Veterinária, Rod PR 317, 6114-Parque Industrial DuzentosDepartment of Animal Morphology and Physiology University of the State of São Paulo (FCAV-UNESP), Via de acesso Prof. Paulo Donato Castellane, s/nDepartment of Animal Science University of California, 1 Shields AveDepartment of Animal Morphology and Physiology University of the State of São Paulo (FCAV-UNESP), Via de acesso Prof. Paulo Donato Castellane, s/nUniversidade de São Paulo (USP)Uningá - Departamento de Medicina VeterináriaUniversidade Estadual Paulista (Unesp)University of CaliforniaSimões, Luciana SennaSasahara, Taís Harumi de CastroFavaron, Phelipe OliveiraLeal, Leonardo Martinsde Oliveira, Fabrício Singaretti [UNESP]Fratini, PaulaBerger, TrishMachado, Marcia Rita Fernandes [UNESP]Miglino, Maria Angélica2021-06-25T10:37:53Z2021-06-25T10:37:53Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1525-1527http://dx.doi.org/10.4067/S0717-95022020000601525International Journal of Morphology, v. 38, n. 6, p. 1525-1527, 2020.0717-95020717-9367http://hdl.handle.net/11449/20677510.4067/S0717-950220200006015252-s2.0-85094876779Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Morphologyinfo:eu-repo/semantics/openAccess2024-06-06T18:41:31Zoai:repositorio.unesp.br:11449/206775Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-06-06T18:41:31Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor La morfología del testículo de paca (Cuniculus paca) con altas dosis de letrozol, un inhibidor de la aromatasa |
| title |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| spellingShingle |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor Simões, Luciana Senna Gonadal Spermatogenesis Toxic |
| title_short |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| title_full |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| title_fullStr |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| title_full_unstemmed |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| title_sort |
The morphology of paca (Cuniculus paca) testis with high dose of letrozole an aromatase inhibitor |
| author |
Simões, Luciana Senna |
| author_facet |
Simões, Luciana Senna Sasahara, Taís Harumi de Castro Favaron, Phelipe Oliveira Leal, Leonardo Martins de Oliveira, Fabrício Singaretti [UNESP] Fratini, Paula Berger, Trish Machado, Marcia Rita Fernandes [UNESP] Miglino, Maria Angélica |
| author_role |
author |
| author2 |
Sasahara, Taís Harumi de Castro Favaron, Phelipe Oliveira Leal, Leonardo Martins de Oliveira, Fabrício Singaretti [UNESP] Fratini, Paula Berger, Trish Machado, Marcia Rita Fernandes [UNESP] Miglino, Maria Angélica |
| author2_role |
author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Uningá - Departamento de Medicina Veterinária Universidade Estadual Paulista (Unesp) University of California |
| dc.contributor.author.fl_str_mv |
Simões, Luciana Senna Sasahara, Taís Harumi de Castro Favaron, Phelipe Oliveira Leal, Leonardo Martins de Oliveira, Fabrício Singaretti [UNESP] Fratini, Paula Berger, Trish Machado, Marcia Rita Fernandes [UNESP] Miglino, Maria Angélica |
| dc.subject.por.fl_str_mv |
Gonadal Spermatogenesis Toxic |
| topic |
Gonadal Spermatogenesis Toxic |
| description |
SUMMARY: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spermatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-12-01 2021-06-25T10:37:53Z 2021-06-25T10:37:53Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4067/S0717-95022020000601525 International Journal of Morphology, v. 38, n. 6, p. 1525-1527, 2020. 0717-9502 0717-9367 http://hdl.handle.net/11449/206775 10.4067/S0717-95022020000601525 2-s2.0-85094876779 |
| url |
http://dx.doi.org/10.4067/S0717-95022020000601525 http://hdl.handle.net/11449/206775 |
| identifier_str_mv |
International Journal of Morphology, v. 38, n. 6, p. 1525-1527, 2020. 0717-9502 0717-9367 10.4067/S0717-95022020000601525 2-s2.0-85094876779 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
International Journal of Morphology |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
1525-1527 |
| dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
| instname_str |
Universidade Estadual Paulista (UNESP) |
| instacron_str |
UNESP |
| institution |
UNESP |
| reponame_str |
Repositório Institucional da UNESP |
| collection |
Repositório Institucional da UNESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
| repository.mail.fl_str_mv |
|
| _version_ |
1803649505672822784 |