The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor

Detalhes bibliográficos
Autor(a) principal: Simoes, Luciana Senna
Data de Publicação: 2020
Outros Autores: Castro Sasahara, Tais Harumi de, Favaron, Phelipe Oliveira, Leal, Leonardo Martins, Oliveira, Fabricio Singaretti de [UNESP], Fratini, Paula, Berger, Trish, Fernandes Machado, Marcia Rita [UNESP], Miglino, Maria Angelica
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/209616
Resumo: The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.
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spelling The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase InhibitorGonadalToxicSpermatogenesisThe study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.Univ Sao Paulo FMVZ USP, Sch Vet Med & Anim Sci, Dept Surg, Av Prof Dr Orlando Marques de Paiva 87, BR-05508270 Sao Paulo, SP, BrazilUninga Dept Med Vet, Fac Ingn, Rod PR 317,6114 Parque Ind Duzentos, BR-87035510 Maringa, PR, BrazilUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, BrazilUniv Calif Davis, Dept Anim Sci, 1 Shields Ave, Davis, CA 95616 USAUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, BrazilSoc Chilena AnatomiaUniversidade de São Paulo (USP)Uninga Dept Med VetUniversidade Estadual Paulista (Unesp)Univ Calif DavisSimoes, Luciana SennaCastro Sasahara, Tais Harumi deFavaron, Phelipe OliveiraLeal, Leonardo MartinsOliveira, Fabricio Singaretti de [UNESP]Fratini, PaulaBerger, TrishFernandes Machado, Marcia Rita [UNESP]Miglino, Maria Angelica2021-06-25T12:24:02Z2021-06-25T12:24:02Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1525-1527International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.0717-9502http://hdl.handle.net/11449/209616WOS:000585776700001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal Of Morphologyinfo:eu-repo/semantics/openAccess2021-10-23T19:28:18Zoai:repositorio.unesp.br:11449/209616Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T19:28:18Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
spellingShingle The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
Simoes, Luciana Senna
Gonadal
Toxic
Spermatogenesis
title_short The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_full The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_fullStr The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_full_unstemmed The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
title_sort The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
author Simoes, Luciana Senna
author_facet Simoes, Luciana Senna
Castro Sasahara, Tais Harumi de
Favaron, Phelipe Oliveira
Leal, Leonardo Martins
Oliveira, Fabricio Singaretti de [UNESP]
Fratini, Paula
Berger, Trish
Fernandes Machado, Marcia Rita [UNESP]
Miglino, Maria Angelica
author_role author
author2 Castro Sasahara, Tais Harumi de
Favaron, Phelipe Oliveira
Leal, Leonardo Martins
Oliveira, Fabricio Singaretti de [UNESP]
Fratini, Paula
Berger, Trish
Fernandes Machado, Marcia Rita [UNESP]
Miglino, Maria Angelica
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Uninga Dept Med Vet
Universidade Estadual Paulista (Unesp)
Univ Calif Davis
dc.contributor.author.fl_str_mv Simoes, Luciana Senna
Castro Sasahara, Tais Harumi de
Favaron, Phelipe Oliveira
Leal, Leonardo Martins
Oliveira, Fabricio Singaretti de [UNESP]
Fratini, Paula
Berger, Trish
Fernandes Machado, Marcia Rita [UNESP]
Miglino, Maria Angelica
dc.subject.por.fl_str_mv Gonadal
Toxic
Spermatogenesis
topic Gonadal
Toxic
Spermatogenesis
description The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-01
2021-06-25T12:24:02Z
2021-06-25T12:24:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.
0717-9502
http://hdl.handle.net/11449/209616
WOS:000585776700001
identifier_str_mv International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.
0717-9502
WOS:000585776700001
url http://hdl.handle.net/11449/209616
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal Of Morphology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1525-1527
dc.publisher.none.fl_str_mv Soc Chilena Anatomia
publisher.none.fl_str_mv Soc Chilena Anatomia
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965681917100032

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